FCCN Level 2 Exam with Questions and Answers

FCCN Level 2 Exam with Questions and Answers Neuromuscular junction ANSWER point of contact between a motor neuron and a skeletal muscle cell -impulse travels down motor axon resulting in influx of calcium -calcium generates release of ACh -ACh crosses into synaptic cleft and binds to receptors -membrane permeability increases, allowing for exchange of Na and K -this initiates depolarization and an action potential, which produces muscle contraction depolarizing agents ANSWER mimic ACh Bind to ACh receptor on motor end plate and depolarize post junctional neuromuscular membrane. paralysis occurs because depolarized membrane can't respond to subsequent stimuli by ACh succinylcholine succinylcholine ANSWER rapid onset 30-60 seconds, ultra short duration, absence of adverse effects on smooth muscle metabolized in blood and excreted by kidneys side effects: hypotension, bradycardia, hyperkalemia, malignant hyperthermia