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ANCC Review Questions (PMHNP IQ)
Questions and Correct Answers/ Latest
Update / Already Graded
What direct-acting dopamine receptor agonist is recommended to be
used in the treatments of neuroleptic malignant syndrome (NMS) fo
help lower the dopamine blockade?
A) benzotropine (Cogentin)
B) bromocriptine (Parlodel)
C) dantrolene (Dantrium)
D) trihexyphenidyl (Artane)
Ans: A) Bromocriptine (Parlodel) is the recommended direct
acting dopamine receptor agonist to help decrease the
dopamine blockade. Danrolene (Dantrium) is a muscle relaxant.
Benzotropine (Cogentin) and Trihexyphenidyl (Artane) are
anticholinergic medications used for extrapyramidal side
effects (EPS).
Mr. Smith is a 56 year old white male who has been successfully
treated on Selegiline for over 4 years. Mr. Smith is going in for elective
surgical procedure. Which medication is strictly contraindicated with
Selegiline?
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A) Non-steroidal anti-inflammatory drugs (NSAIDS)
B) Codeine
C) Morphine
D) Meperidine
Ans: D) Meperidine is strictly prohibited when a patient is
treated on a monoamine oxidase inhibitor (MAOI) due to the
risk of hypertensive crisis and death.
A WBC of 4,000 in a patient taking Clozapine would prompt the
PMHNP to take which of the following actions?
A) Consult with hematologist to determine appropriate antibiotic
regimen and monitor closely.
B) Institute twice-weekly complete blood count with differentials and
monitor closely.
C) Discontinue clozapine, initiate alternative antipsychotic medication
and monitor closely.
D) Institute daily complete blood count with differentials and monitor
closely.
Ans: B) Institute twice-weekly complete blood count with
differentials and monitor closely.
All rights reserved © 2025/ 2026 |
, Page |3
The recommended cut-points for discontinuation of clozapine
are WBC of 2,000 to 3,000 or granulocytes of 1,000 to 1,500 for
agranulocytosis and severely compromised immune system. At
a WBC of 4,000, the recommendation is to closely monitor CBC
with differential twice a week while patient may continue
clozapine in the absence of any other signs or symptoms.
A patient with a diagnosis of schizophrenia has a history of suicidal
ideation and suicide attempts. The PMHNP should consider which
antipsychotic medication that is the only antipsychotic to reduce the
risk of suicide in schizophrenia?
A) Abilify (aripriprazole)
B) Latuda (lurasidone)
C) Invega (iloperidone)
D) Clozaril (clozapine)
Ans: D) Clozaril (clozapine) is the only known antipsychotic
medication that had been shown to reduce the risk of suicide in
patients diagnosed with schizophrenia.
A patient being treated for major depressive disorder and on sertraline
(Zoloft), 150 mg po daily for the past 16 years, presents to the
All rights reserved © 2025/ 2026 |
ANCC Review Questions (PMHNP IQ)
Questions and Correct Answers/ Latest
Update / Already Graded
What direct-acting dopamine receptor agonist is recommended to be
used in the treatments of neuroleptic malignant syndrome (NMS) fo
help lower the dopamine blockade?
A) benzotropine (Cogentin)
B) bromocriptine (Parlodel)
C) dantrolene (Dantrium)
D) trihexyphenidyl (Artane)
Ans: A) Bromocriptine (Parlodel) is the recommended direct
acting dopamine receptor agonist to help decrease the
dopamine blockade. Danrolene (Dantrium) is a muscle relaxant.
Benzotropine (Cogentin) and Trihexyphenidyl (Artane) are
anticholinergic medications used for extrapyramidal side
effects (EPS).
Mr. Smith is a 56 year old white male who has been successfully
treated on Selegiline for over 4 years. Mr. Smith is going in for elective
surgical procedure. Which medication is strictly contraindicated with
Selegiline?
All rights reserved © 2025/ 2026 |
, Page |2
A) Non-steroidal anti-inflammatory drugs (NSAIDS)
B) Codeine
C) Morphine
D) Meperidine
Ans: D) Meperidine is strictly prohibited when a patient is
treated on a monoamine oxidase inhibitor (MAOI) due to the
risk of hypertensive crisis and death.
A WBC of 4,000 in a patient taking Clozapine would prompt the
PMHNP to take which of the following actions?
A) Consult with hematologist to determine appropriate antibiotic
regimen and monitor closely.
B) Institute twice-weekly complete blood count with differentials and
monitor closely.
C) Discontinue clozapine, initiate alternative antipsychotic medication
and monitor closely.
D) Institute daily complete blood count with differentials and monitor
closely.
Ans: B) Institute twice-weekly complete blood count with
differentials and monitor closely.
All rights reserved © 2025/ 2026 |
, Page |3
The recommended cut-points for discontinuation of clozapine
are WBC of 2,000 to 3,000 or granulocytes of 1,000 to 1,500 for
agranulocytosis and severely compromised immune system. At
a WBC of 4,000, the recommendation is to closely monitor CBC
with differential twice a week while patient may continue
clozapine in the absence of any other signs or symptoms.
A patient with a diagnosis of schizophrenia has a history of suicidal
ideation and suicide attempts. The PMHNP should consider which
antipsychotic medication that is the only antipsychotic to reduce the
risk of suicide in schizophrenia?
A) Abilify (aripriprazole)
B) Latuda (lurasidone)
C) Invega (iloperidone)
D) Clozaril (clozapine)
Ans: D) Clozaril (clozapine) is the only known antipsychotic
medication that had been shown to reduce the risk of suicide in
patients diagnosed with schizophrenia.
A patient being treated for major depressive disorder and on sertraline
(Zoloft), 150 mg po daily for the past 16 years, presents to the
All rights reserved © 2025/ 2026 |
