Psychiatric Pharmacology: NCLEX Review for
Medications, Hormonal Therapy, and Patient
Safety |Latest Updated 2026 Rationales Graded
A+
Prostate Cancer
Testosterone-sensitive cancer.
Endometrial/Breast Cancer
Estrogen-sensitive cancers.
Menopause
Cessation of ovaries producing estrogen. Post-menopause leads to osteoporosis. Diagnosed
after 12 months without bleeding.
HRT
Estrogen replacement.
Non-HRT
Black Cohosh (Estrogen Agonist) for hot flashes.
Osteoporosis Tx
Lack of estrogen causes bone density loss.
Dexascan
Measures bone density.
Fosamax (Alendronate Sodium)
Take on empty stomach with 8oz water and SIT UP for 30-60 min.
PMDD
Severe psychological component (suicidal ideation, extreme depression).
PMDD Tx
, SSRIs (first-line), Oral Contraceptives.
Endometriosis
Uterine tissue forms outside the uterus (stimulated by hormones). Major cause of infertility.
Med Interactions
St. John's Wort, Rifampin, Charcoal decrease efficacy of OCs.
Viagra (Sildenafil)
Contraindicated with Nitrates (e.g., nitroglycerin) due to risk of severe hypotension.
Combined OCs
Estrogen & Progesterone.
Progesterone-Only (POP, Depo, Implant, Hormonal IUD)
Progesterone only.
POP
Must take at the exact same time daily (short 24 hr half-life).
Depo
Can cause weight gain; fertility return may be delayed.
Implant
Effective for 3 years.
Biofeedback/NFP
BBT, Cervical Mucus, Calendar.
EC vs. Abortifacient
EC (Plan B/Copper IUD): Prevents pregnancy (delays ovulation/inhibits sperm).
Abortifacient (Misoprostol)
Terminates established pregnancy (<8 wks) via cervical ripening/contractions.
Methotrexate
Treats ectopic pregnancy.
Copper IUD