Blood Bank-Final Exam Questions and
Answers | Latest Version | 2025/2026 |
Correct & Verified
What is the primary purpose of blood typing before transfusion?
✔✔To ensure donor and recipient blood are compatible and prevent transfusion reactions.
Which blood group antigen is most immunogenic after ABO?
✔✔Rh (D) antigen.
What is the universal donor blood type for red blood cells?
✔✔O negative.
What is the universal recipient blood type for red blood cells?
✔✔AB positive.
Which component of blood is mainly responsible for oxygen transport?
✔✔Red blood cells.
What anticoagulant is commonly used in blood collection bags?
✔✔CPDA-1 (Citrate Phosphate Dextrose Adenine).
What test is used to detect unexpected antibodies in a patient’s serum?
1
,✔✔Antibody screen.
Which test confirms compatibility between donor and recipient blood?
✔✔Crossmatch.
What is the primary function of platelets?
✔✔Blood clot formation.
Which plasma protein is essential for clotting?
✔✔Fibrinogen.
What is hemolysis?
✔✔Destruction of red blood cells.
Which condition occurs when incompatible blood is transfused?
✔✔Acute hemolytic transfusion reaction.
What is the shelf life of refrigerated packed red blood cells?
✔✔35 to 42 days depending on preservative.
Which blood component is used to treat thrombocytopenia?
✔✔Platelet concentrate.
2
,What blood product is used to replace clotting factors?
✔✔Fresh frozen plasma.
What is the main function of cryoprecipitate?
✔✔To provide fibrinogen and factor VIII.
What is the major cause of delayed hemolytic transfusion reactions?
✔✔Secondary immune response to minor antigens.
Which test is used to detect antibodies bound to red cells in vivo?
✔✔Direct antiglobulin test (DAT).
Which test detects free antibodies in a patient’s serum?
✔✔Indirect antiglobulin test (IAT).
What is the primary goal of leukoreduction?
✔✔To reduce febrile reactions and CMV transmission risk.
Which disease is commonly screened in donated blood?
✔✔HIV.
3
, What is the minimum hemoglobin requirement for blood donors?
✔✔Typically 12.5 g/dL or higher.
Which blood group system is second most clinically significant after ABO?
✔✔Rh system.
What is the purpose of a type and screen test?
✔✔To determine ABO/Rh type and detect unexpected antibodies.
What does a positive crossmatch indicate?
✔✔Incompatibility between donor and recipient.
What is plasma mainly composed of?
✔✔Water and plasma proteins.
Which blood product is preferred for massive blood loss?
✔✔Packed red blood cells with plasma support.
What is the primary risk of transfusing outdated blood?
✔✔Reduced red cell viability and function.
What is alloimmunization?
4
Answers | Latest Version | 2025/2026 |
Correct & Verified
What is the primary purpose of blood typing before transfusion?
✔✔To ensure donor and recipient blood are compatible and prevent transfusion reactions.
Which blood group antigen is most immunogenic after ABO?
✔✔Rh (D) antigen.
What is the universal donor blood type for red blood cells?
✔✔O negative.
What is the universal recipient blood type for red blood cells?
✔✔AB positive.
Which component of blood is mainly responsible for oxygen transport?
✔✔Red blood cells.
What anticoagulant is commonly used in blood collection bags?
✔✔CPDA-1 (Citrate Phosphate Dextrose Adenine).
What test is used to detect unexpected antibodies in a patient’s serum?
1
,✔✔Antibody screen.
Which test confirms compatibility between donor and recipient blood?
✔✔Crossmatch.
What is the primary function of platelets?
✔✔Blood clot formation.
Which plasma protein is essential for clotting?
✔✔Fibrinogen.
What is hemolysis?
✔✔Destruction of red blood cells.
Which condition occurs when incompatible blood is transfused?
✔✔Acute hemolytic transfusion reaction.
What is the shelf life of refrigerated packed red blood cells?
✔✔35 to 42 days depending on preservative.
Which blood component is used to treat thrombocytopenia?
✔✔Platelet concentrate.
2
,What blood product is used to replace clotting factors?
✔✔Fresh frozen plasma.
What is the main function of cryoprecipitate?
✔✔To provide fibrinogen and factor VIII.
What is the major cause of delayed hemolytic transfusion reactions?
✔✔Secondary immune response to minor antigens.
Which test is used to detect antibodies bound to red cells in vivo?
✔✔Direct antiglobulin test (DAT).
Which test detects free antibodies in a patient’s serum?
✔✔Indirect antiglobulin test (IAT).
What is the primary goal of leukoreduction?
✔✔To reduce febrile reactions and CMV transmission risk.
Which disease is commonly screened in donated blood?
✔✔HIV.
3
, What is the minimum hemoglobin requirement for blood donors?
✔✔Typically 12.5 g/dL or higher.
Which blood group system is second most clinically significant after ABO?
✔✔Rh system.
What is the purpose of a type and screen test?
✔✔To determine ABO/Rh type and detect unexpected antibodies.
What does a positive crossmatch indicate?
✔✔Incompatibility between donor and recipient.
What is plasma mainly composed of?
✔✔Water and plasma proteins.
Which blood product is preferred for massive blood loss?
✔✔Packed red blood cells with plasma support.
What is the primary risk of transfusing outdated blood?
✔✔Reduced red cell viability and function.
What is alloimmunization?
4
