TEST BANK
j
Genetics and Genomics in Nursing and Health Care
j j j j j j j
by Theresa A. Beery, M. Linda Workman
j j j j j j
First Edition
j
FULL TEST BANK!!! j j
, Chapterj1:jDNAjStructurejandjFunction
MultiplejChoice
Identifyjthejchoicejthatjbestjcompletesjthejstatementjorjanswersjthejquestion.
jj A. 1.j Injwhichjbodyjorjcelljareajarejmostjgenesjinjhumansjlocated?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasmajmembrane
jj A. 2.j Whichjconditionjorjstatementjexemplifiesjthejconceptjofjgenomicsjratherjthanjgenetics?
A. Thejgenejforjinsulinjisjlocatedjonjchromosomej11jinjalljpeople.
B. Expressionjofjanyjsinglejgenejisjdependentjonjinheritingjtwojalleles.
C. Sex-linkedjrecessivejdisordersjaffectjmalesjmorejoftenjthanjfemales.
D. Onejallelejforjeachjgenejisjinheritedjfromjthejmother,jandjonejisjinheritedjfromjthejfat
her.
jj A. 3.j WhatjisjthejpurposejofjphosphorousjinjajDNAjstrand?
A. Linkingjthejnucleotidesjintojajstrand
B. Holdingjcomplementaryjstrandsjtogether
C. Ensuringjthatjajpurinejisjalwaysjpairedjwithjajpyrimidine
D. Preventingjthejseparationjofjdouble-strandedjDNAjintojsingle-strandedjDNA
j A.
4.jWhatjisjthejtermjusedjtojdefinejalternativejformsjofjajgenejthatjmayjresultjinjdifferentjexp
ressionjofjthejtraitjcodedjforjbyjthatjgene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
j D. 5.jWhatjpercentagejofjbasesjinjajstretchjofjdouble-
strandedjDNAjthatjcontainsj30%jguaninej(G)jbasesjwouldjbejadeninej(A)?
A. 70%
B. 60%
C. 30%
D. 20%
j C.
6.jWhatjisjthejtermjusedjtojdescribejthejorganizedjpicturejofjthejpairedjchromosomesjwith
injajcelljusedjtojdeterminejwhetherjchromosomejnumbers,jstructures,jandjbandingjpatternsjarejno
rmal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
j D.
7.jWhatjwouldjbejthejsequencejofjDNAjthatjisjcomplementaryjtojajDNAjsectionjwithjt
hejbasejsequencejofjGGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
,jj B. 8.j Whichjofjthesejcomplementaryjbasejpairsjformjthejstrongestjorj“tightest”jassociation?
A. Adeninejandjthymine
B. Cytosinejandjguanine
C. Guaninejandjthymine
D. Cytosinejandjadenine
jj A 9.j WhatjactivityjoccursjduringjMjphasejofjthejcelljcycle?
A. Thejcelljundergoesjcytokinesis.
B. Activityjstops,jandjthejcellj“sleeps.”
C. AlljDNAjisjcompletelyjreplicated.
D. Thejcelljgreatlyjincreasesjproteinjsynthesis.
jj B.j j 10.j Whichjchromosomejnumberjrepresentsjthejeuploidjstatejforjnormaljhumanjsomaticjcells?
A. 44
B. 46
C. 47
D. 48
jj A.j 11.j Howjdoesjthejproteomejdifferjfromjthejgenome?
A. Thejproteomejchangesjinjresponsejtojintracellularjandjextracellularjsignals.
B. Thejgenomejchangesjinjresponsejtojintracellularjandjextracellularjsignals.
C. Thejproteomejisjstablejinjsomaticjcellsjandjunstablejinjgermjcells,jwhereasjthejge
nomejisjstablejinjbothjsomaticjcellsjandjgermjcells.
D. Thejgenomejisjstablejinjsomaticjcellsjandjunstablejinjgermjcells,jwhereasjthejpr
oteomejisjstablejinjbothjsomaticjcellsjandjgermjcells.
jj C.j j 12.j Whatjisjthejmostjoutstandingjfeaturejofjajmaturejhaploidjcell?
A. Itjisjusuallyjhomozygous.
B. Thejsexjchromosomesjarejmissing.
C. Onlyjonejchromosomejofjeachjpairjisjpresent.
D. DNAjsynthesisjoccursjafterjmitosisjinsteadjofjbefore.
jj D.j j 13.j Atjwhatjphasejofjthejcelljcyclejarejchromosomesjvisiblejasjseparatejstructures?
A. G1
B. G2
C. S
D. M
jj B.j 14.j WhichjstatementjaboutjthejcelljcyclejphasejofjG0j isjtrue?
A. Hyperplasticjgrowthjinjplacejofjhypertrophicjgrowth
B. Performancejofjspecificjdifferentiatedjfunctions
C. Initiationjandjcompletionjofjnucleokinesis
D. ReplicationjofjDNA
jj B.j 15.j WhatjisjthejresultjofjnormaljDNAjreplication?
A. Formationjofjtwojnewjdaughterjcells
B. FormationjofjtwojidenticaljsetsjofjDNA
C. Disappearancejofjthejoriginaljparentjcell
D. Activationjandjattachmentjofjspindlejfibers
, jj A.j 16.j Whichjstatementjregardingjchromosomejstructurejorjfunctionjisjtrue?
A. Thejchromatidsjofjanyjsinglejchromosomejarejknownjasj“sisterjchromatids.”
B. Thejgenesjlocatedjonjthejtelomeresjofjchromosomesjarejidenticaljtojthejgenesjinjth
ejcentromeres.
C. Immediatelyjbeforejthejmitosisjphasejofjcelljdivision,jthejchromosomesjofjalljso
maticjcellsjarejhaploid.
D. Ajspecificjgenejallelejonjonejchromosomejhasjajcomplementaryjallelejonjthejotherjch
romosomejofjajpair.
jj C.j j 17.j Whyjdoesjajpersonjwithjnormaljchromosomesjonlyjhavejtwojallelesjforjanyjsinglejgenejtrait?
A. Ajminimumjofjtwojallelesjisjrequiredjforjthejexpressionjofjmonogenicjtraits.
B. Whenjajdominantjallelejisjpairedjwithjajrecessivejallele,jonlyjthejdominantjallelejisjex
pressed,jandjthejrecessivejallelejisjsilent.
C. Onejallelejforjthejmonogenicjtraitjisjonjthejpaternallyjderivedjchromosome,jandjth
ejotherjallelejisjonjthejmaternallyjderivedjchromosome.
D. Expressionjofjmorejthanjtwojallelesjofjanyjsingle-
genejtraitjresultsjinjenhancedjexpressionjofjrecessivejallelesjandjsuppressedjexpr
essionjofjdominantjalleles.
jj C 18.j Underjwhatjnormaljconditionjarejgenotypejandjphenotypejalwaysjthejsame?
A. Euploidyjofjalleles
B. Aneuploidyjofjalleles
C. Homozygosityjofjalleles
D. Heterozygosityjofjalleles
j j D.j 19.j WhatjwouldjbejthejexpectedjresultjofjajdrugjthatjaffectedjajparticularjtissuejbyjcausingjnewjDNAjt
ojformjwithjcovalentjbondsjinsteadjofjhydrogenjbonds?
A. NonejofjthejcellsjinjthejaffectedjtissuejwouldjbejablejtojleavejG0j andjenterjthejcelljcyc
le.
B. ReplicationjofjDNAjwouldjresultjinjidenticaljDNAjstrandsjinsteadjofjc
omplementaryjstrands.
C. Mitosisjofjcellsjinjthejtissuejwouldjresultjinjthejproductionjofjthreejnewjdaughterjcel
lsjinsteadjofjjustjtwo.
D. Thejnewjcellsjthatjformedjwithinjthisjtissuejwouldjnotjbejablejtojcompletejthejnextjrou
ndjofjmitosisjsuccessfully.
jj B.j 20.j HowjdoesjthejDNAjenzymejtopoisomerasejcontributejtojDNAjreplication?
A. Unwindsjthejdoublejhelixjandjseparatesjthejdouble-strandedjDNA
B. Createsjaj“nick”jinjthejDNAjsupercoils,jallowingjthemjtojstraightenjbeforejre
plication
C. InitiatesjDNAjsynthesisjinjmultiplejsitesjdownjthejstrand,jmakingjthejprocessjmorejeff
icient
D. ConnectsjandjlinksjthejindividualjpiecesjofjnewlyjsynthesizedjDNAjtojformjajsi
nglejstrand
jj A.j 21.j WherejisjtelomericjDNAjlocated?
A. Atjthejtipsjofjthejpjandjqjarmsjofjchromosomes.
B. Injthejmitochondriajofjalljsomaticjcells
C. Onlyjinjthejgermjcellsj(ovajandjsperm)
D. Withinjthejhistonesjofjthejsolenoid
j
Genetics and Genomics in Nursing and Health Care
j j j j j j j
by Theresa A. Beery, M. Linda Workman
j j j j j j
First Edition
j
FULL TEST BANK!!! j j
, Chapterj1:jDNAjStructurejandjFunction
MultiplejChoice
Identifyjthejchoicejthatjbestjcompletesjthejstatementjorjanswersjthejquestion.
jj A. 1.j Injwhichjbodyjorjcelljareajarejmostjgenesjinjhumansjlocated?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasmajmembrane
jj A. 2.j Whichjconditionjorjstatementjexemplifiesjthejconceptjofjgenomicsjratherjthanjgenetics?
A. Thejgenejforjinsulinjisjlocatedjonjchromosomej11jinjalljpeople.
B. Expressionjofjanyjsinglejgenejisjdependentjonjinheritingjtwojalleles.
C. Sex-linkedjrecessivejdisordersjaffectjmalesjmorejoftenjthanjfemales.
D. Onejallelejforjeachjgenejisjinheritedjfromjthejmother,jandjonejisjinheritedjfromjthejfat
her.
jj A. 3.j WhatjisjthejpurposejofjphosphorousjinjajDNAjstrand?
A. Linkingjthejnucleotidesjintojajstrand
B. Holdingjcomplementaryjstrandsjtogether
C. Ensuringjthatjajpurinejisjalwaysjpairedjwithjajpyrimidine
D. Preventingjthejseparationjofjdouble-strandedjDNAjintojsingle-strandedjDNA
j A.
4.jWhatjisjthejtermjusedjtojdefinejalternativejformsjofjajgenejthatjmayjresultjinjdifferentjexp
ressionjofjthejtraitjcodedjforjbyjthatjgene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
j D. 5.jWhatjpercentagejofjbasesjinjajstretchjofjdouble-
strandedjDNAjthatjcontainsj30%jguaninej(G)jbasesjwouldjbejadeninej(A)?
A. 70%
B. 60%
C. 30%
D. 20%
j C.
6.jWhatjisjthejtermjusedjtojdescribejthejorganizedjpicturejofjthejpairedjchromosomesjwith
injajcelljusedjtojdeterminejwhetherjchromosomejnumbers,jstructures,jandjbandingjpatternsjarejno
rmal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
j D.
7.jWhatjwouldjbejthejsequencejofjDNAjthatjisjcomplementaryjtojajDNAjsectionjwithjt
hejbasejsequencejofjGGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
,jj B. 8.j Whichjofjthesejcomplementaryjbasejpairsjformjthejstrongestjorj“tightest”jassociation?
A. Adeninejandjthymine
B. Cytosinejandjguanine
C. Guaninejandjthymine
D. Cytosinejandjadenine
jj A 9.j WhatjactivityjoccursjduringjMjphasejofjthejcelljcycle?
A. Thejcelljundergoesjcytokinesis.
B. Activityjstops,jandjthejcellj“sleeps.”
C. AlljDNAjisjcompletelyjreplicated.
D. Thejcelljgreatlyjincreasesjproteinjsynthesis.
jj B.j j 10.j Whichjchromosomejnumberjrepresentsjthejeuploidjstatejforjnormaljhumanjsomaticjcells?
A. 44
B. 46
C. 47
D. 48
jj A.j 11.j Howjdoesjthejproteomejdifferjfromjthejgenome?
A. Thejproteomejchangesjinjresponsejtojintracellularjandjextracellularjsignals.
B. Thejgenomejchangesjinjresponsejtojintracellularjandjextracellularjsignals.
C. Thejproteomejisjstablejinjsomaticjcellsjandjunstablejinjgermjcells,jwhereasjthejge
nomejisjstablejinjbothjsomaticjcellsjandjgermjcells.
D. Thejgenomejisjstablejinjsomaticjcellsjandjunstablejinjgermjcells,jwhereasjthejpr
oteomejisjstablejinjbothjsomaticjcellsjandjgermjcells.
jj C.j j 12.j Whatjisjthejmostjoutstandingjfeaturejofjajmaturejhaploidjcell?
A. Itjisjusuallyjhomozygous.
B. Thejsexjchromosomesjarejmissing.
C. Onlyjonejchromosomejofjeachjpairjisjpresent.
D. DNAjsynthesisjoccursjafterjmitosisjinsteadjofjbefore.
jj D.j j 13.j Atjwhatjphasejofjthejcelljcyclejarejchromosomesjvisiblejasjseparatejstructures?
A. G1
B. G2
C. S
D. M
jj B.j 14.j WhichjstatementjaboutjthejcelljcyclejphasejofjG0j isjtrue?
A. Hyperplasticjgrowthjinjplacejofjhypertrophicjgrowth
B. Performancejofjspecificjdifferentiatedjfunctions
C. Initiationjandjcompletionjofjnucleokinesis
D. ReplicationjofjDNA
jj B.j 15.j WhatjisjthejresultjofjnormaljDNAjreplication?
A. Formationjofjtwojnewjdaughterjcells
B. FormationjofjtwojidenticaljsetsjofjDNA
C. Disappearancejofjthejoriginaljparentjcell
D. Activationjandjattachmentjofjspindlejfibers
, jj A.j 16.j Whichjstatementjregardingjchromosomejstructurejorjfunctionjisjtrue?
A. Thejchromatidsjofjanyjsinglejchromosomejarejknownjasj“sisterjchromatids.”
B. Thejgenesjlocatedjonjthejtelomeresjofjchromosomesjarejidenticaljtojthejgenesjinjth
ejcentromeres.
C. Immediatelyjbeforejthejmitosisjphasejofjcelljdivision,jthejchromosomesjofjalljso
maticjcellsjarejhaploid.
D. Ajspecificjgenejallelejonjonejchromosomejhasjajcomplementaryjallelejonjthejotherjch
romosomejofjajpair.
jj C.j j 17.j Whyjdoesjajpersonjwithjnormaljchromosomesjonlyjhavejtwojallelesjforjanyjsinglejgenejtrait?
A. Ajminimumjofjtwojallelesjisjrequiredjforjthejexpressionjofjmonogenicjtraits.
B. Whenjajdominantjallelejisjpairedjwithjajrecessivejallele,jonlyjthejdominantjallelejisjex
pressed,jandjthejrecessivejallelejisjsilent.
C. Onejallelejforjthejmonogenicjtraitjisjonjthejpaternallyjderivedjchromosome,jandjth
ejotherjallelejisjonjthejmaternallyjderivedjchromosome.
D. Expressionjofjmorejthanjtwojallelesjofjanyjsingle-
genejtraitjresultsjinjenhancedjexpressionjofjrecessivejallelesjandjsuppressedjexpr
essionjofjdominantjalleles.
jj C 18.j Underjwhatjnormaljconditionjarejgenotypejandjphenotypejalwaysjthejsame?
A. Euploidyjofjalleles
B. Aneuploidyjofjalleles
C. Homozygosityjofjalleles
D. Heterozygosityjofjalleles
j j D.j 19.j WhatjwouldjbejthejexpectedjresultjofjajdrugjthatjaffectedjajparticularjtissuejbyjcausingjnewjDNAjt
ojformjwithjcovalentjbondsjinsteadjofjhydrogenjbonds?
A. NonejofjthejcellsjinjthejaffectedjtissuejwouldjbejablejtojleavejG0j andjenterjthejcelljcyc
le.
B. ReplicationjofjDNAjwouldjresultjinjidenticaljDNAjstrandsjinsteadjofjc
omplementaryjstrands.
C. Mitosisjofjcellsjinjthejtissuejwouldjresultjinjthejproductionjofjthreejnewjdaughterjcel
lsjinsteadjofjjustjtwo.
D. Thejnewjcellsjthatjformedjwithinjthisjtissuejwouldjnotjbejablejtojcompletejthejnextjrou
ndjofjmitosisjsuccessfully.
jj B.j 20.j HowjdoesjthejDNAjenzymejtopoisomerasejcontributejtojDNAjreplication?
A. Unwindsjthejdoublejhelixjandjseparatesjthejdouble-strandedjDNA
B. Createsjaj“nick”jinjthejDNAjsupercoils,jallowingjthemjtojstraightenjbeforejre
plication
C. InitiatesjDNAjsynthesisjinjmultiplejsitesjdownjthejstrand,jmakingjthejprocessjmorejeff
icient
D. ConnectsjandjlinksjthejindividualjpiecesjofjnewlyjsynthesizedjDNAjtojformjajsi
nglejstrand
jj A.j 21.j WherejisjtelomericjDNAjlocated?
A. Atjthejtipsjofjthejpjandjqjarmsjofjchromosomes.
B. Injthejmitochondriajofjalljsomaticjcells
C. Onlyjinjthejgermjcellsj(ovajandjsperm)
D. Withinjthejhistonesjofjthejsolenoid
