Test Bank for Pharmacotherapeutics for Advanced Practice 5th Ed. | Arcangelo

TEST BANK j


PharmacotherapeuticsjforjAdvancedjPractice:jAjPracticaljApproach

byjVirginiajPoolejArcangelo,jAndrewjM.jPeterson
FifthjEdition




FULL TEST BANK!!!
j j

,Chapterj1jIssuesjforjthejPractitionerjinjDrugjTherapy

MULTIPLEjCHOICE

1. Nursejpractitionerjprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursingjforjeachjstate
D. ThejStatejBoardjofjPharmacy

ANS:j C PTS:j 1

2. PhysicianjAssistantj(PA)jprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursing
D. ThejStatejBoardjofjMedicaljExaminers

ANS:j D PTS:j 1

3. Clinicaljjudgmentjinjprescribingjincludes:
A. Factoringjinjthejcostjtojthejpatientjofjthejmedicationjprescribed
B. Alwaysjprescribingjthejnewestjmedicationjavailablejforjthejdiseasejprocess
C. Handingjoutjdrugjsamplesjtojpoorjpatients
D. Prescribingjalljgenericjmedicationsjtojcutjcosts

ANS:j A PTS:j 1

4. Criteriajforjchoosingjanjeffectivejdrugjforjajdisorderjinclude:
A. Askingjthejpatientjwhatjdrugjtheyjthinkjwouldjworkjbestjforjthem
B. Consultingjnationallyjrecognizedjguidelinesjforjdiseasejmanagement
C. Prescribingjmedicationsjthatjarejavailablejasjsamplesjbeforejwritingjajprescription
D. FollowingjU.S.jDrugjEnforcementjAdministrationj(DEA)jguidelinesjforjp
rescribing
ANS:j B PTS:j 1

5. Nursejpractitionerjpracticejmayjthrivejunderjhealth-carejreformjduejto:
A. Thejdemonstratedjabilityjofjnursejpractitionersjtojcontroljcostsjandjimprovejpatientjo
utcomes
B. Thejfactjthatjnursejpractitionersjwilljbejablejtojpracticejindependently
C. Thejfactjthatjnursejpractitionersjwilljhavejfulljreimbursementjunderjhealth-
carejreform
D. ThejabilityjtojshiftjaccountabilityjforjMedicaidjtojthejstatejlevel
ANS:j A PTS:j 1

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Chapterj2.PharmacokineticjBasisjofjTherapeuticsjandjPharmacodynamic

MULTIPLEjCHOICE

1. Ajpatient'sjnutritionaljintakejandjlabjworkjreflectsjhypoalbuminemia.jThisjisjcriticaljtojpr
escribingjbecause:
A. Distributionjofjdrugsjtojtargetjtissuejmayjbejaffected
B. Thejsolubilityjofjthejdrugjwilljnotjmatchjthejsitejofjabsorption
C. Therejwilljbejlessjfreejdrugjavailablejtojgeneratejanjeffect
D. Drugsjboundjtojalbuminjarejreadilyjexcretedjbyjthejkidney

ANS:j A PTS:j 1

2. Drugsjthatjhavejajsignificantjfirst-passjeffect:
A. Mustjbejgivenjbyjthejenteralj(oral)jroutejonly
B. Bypassjthejhepaticjcirculation
C. Arejrapidlyjmetabolizedjbyjthejliverjandjmayjhavejlittlejifjanyjdesiredjaction
D. Arejconvertedjbyjthejliverjtojmorejactivejandjfat-solublejforms

ANS:j C PTS:j 1

3. Thejroutejofjexcretionjofjajvolatilejdrugjwilljlikelyjbe:
A. Thejkidneys
B. Thejlungs
C. Thejbilejandjfeces
D. Thejskin

ANS:j B PTS:j 1

4. Medroxyprogesteronej(DepojProvera)jisjprescribedjIMjtojcreatejajstoragejreservoirjofjthejdr
ug.jStoragejreservoirs:
A. Assurejthatjthejdrugjwilljreachjitsjintendedjtargetjtissue
B. Arejthejreasonjforjgivingjloadingjdoses
C. Increasejthejlengthjofjtimejajdrugjisjavailablejandjactive
D. Arejmostjcommonjinjcollagenjtissues

ANS:j C PTS:j 1

5. ThejNPjchoosesjtojgivejcephalexinjeveryj8jhoursjbasedjonjknowledgejofjthejdrug's:
A. Propensityjtojgojtojthejtargetjreceptor
B. Biologicaljhalf-life
C. Pharmacodynamics
D. Safetyjandjsidejeffects

ANS:j B PTS:j 1

6. Azithromycinjdosingjrequiresjthejfirstjday'sjdosejbejtwicejthosejofjthejotherj4jdaysjofjthejpre
scription.jThisjisjconsideredjajloadingjdose.jAjloadingjdose:
A. Rapidlyjachievesjdrugjlevelsjinjthejtherapeuticjrange
B. Requiresjfourjtojfivejhalf-livesjtojattain
C. Isjinfluencedjbyjrenaljfunction

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D. Isjdirectlyjrelatedjtojthejdrugjcirculatingjtojthejtargetjtissues
ANS:j A PTS:j j 1

7. Thejpointjinjtimejonjthejdrugjconcentrationjcurvejthatjindicatesjthejfirstjsignjofjajtherapeuticjeff
ectjisjthe:
A. Minimumjadversejeffectjlevel
B. Peakjofjaction
C. Onsetjofjaction
D. Therapeuticjrange

ANS:j C PTS:j 1

8. Phenytoinjrequiresjajtroughjleveljbejdrawn.jPeakjandjtroughjlevelsjarejdone:
A. Whenjthejdrugjhasjajwidejtherapeuticjrange
B. Whenjthejdrugjwilljbejadministeredjforjajshortjtimejonly
C. Whenjtherejisjajhighjcorrelationjbetweenjthejdosejandjsaturationjofjreceptorjsites
D. Tojdeterminejifjajdrugjisjinjthejtherapeuticjrange

ANS:j D PTS:j 1

9. Ajlaboratoryjresultjindicatesjthejpeakjleveljforjajdrugjisjabovejthejminimumjtoxicjco
ncentration.jThisjmeansjthatjthe:
A. Concentrationjwilljproducejtherapeuticjeffects
B. Concentrationjwilljproducejanjadversejresponse
C. Timejbetweenjdosesjmustjbejshortened
D. Durationjofjactionjofjthejdrugjisjtoojlong

ANS:j B PTS:j 1

10. Drugsjthatjarejreceptorjagonistsjmayjdemonstratejwhatjproperty?
A. Irreversiblejbindingjtojthejdrugjreceptorjsite
B. Up-regulationjwithjchronicjuse
C. Desensitizationjorjdown-regulationjwithjcontinuousjuse
D. Inversejrelationshipjbetweenjdrugjconcentrationjandjdrugjaction

ANS:j C PTS:j 1

11. Drugsjthatjarejreceptorjantagonists,jsuchjasjbetajblockers,jmayjcause:
A. Down-regulationjofjthejdrugjreceptor
B. Anjexaggeratedjresponsejifjabruptlyjdiscontinued
C. Partialjblockadejofjthejeffectsjofjagonistjdrugs
D. Anjexaggeratedjresponsejtojcompetitivejdrugjagonists

ANS:j B PTS:j 1

12. Factorsjthatjaffectjgastricjdrugjabsorptionjinclude:
A. Liverjenzymejactivity
B. Protein-bindingjpropertiesjofjthejdrugjmolecule
C. Lipidjsolubilityjofjthejdrug
D. Abilityjtojchewjandjswallow

ANS:j C PTS:j 1




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