UNE Medical Biochemistry Unit 3 Midterm
Test Exam With 100% Correct Answers
In the fasted state, fatty acyl-CoA are transported across the mitochondrial
membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPTI)
can be directly inhibited by which of the following compounds?
a. Malonyl CoA
b. Carnitine
c. Acetyl CoA
d. Palmitate
Malonyl CoA
Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will
activate which of the following enzymes?
a. glycogen synthase
b. lipoprotein lipase
c. hormone sensitive lipase
d. pyruvate dehydrogenase complex
hormone sensitive lipase
, ATP can be generated by many metabolic pathways in the body. Which of the
following processes generates the most ATP?
a. glycogenolysis
b. fatty acid β-oxidation
c. pentose phosphate pathway
d. citric acid cycle
Fatty acid β-oxidation
In liver, which of the following key inhibitory events ensures that newly
synthesized palmitoyl-CoA is not immediately oxidized?
a. Inhibition of CPT-II by acetyl-CoA
b. Inhibition of CPT-I by malonyl-CoA
c. Inhibition of CPT-I by palmitoyl-carnitine
d. Inhibition of acyl-CoA synthetase by malonyl-CoA
Inhibition of CPT-I by malonyl-CoA
Ketonuria, hyperglycemia and severe acidosis are prime diagnostic indicators of
the presentation of Type I diabetic ketoacidosis. Which of the following
compounds are "ketone bodies" that would be elevated in serum and urine of a
patient in this condition?
a. fumarate and succinate
b. pyruvate and lactate
Test Exam With 100% Correct Answers
In the fasted state, fatty acyl-CoA are transported across the mitochondrial
membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPTI)
can be directly inhibited by which of the following compounds?
a. Malonyl CoA
b. Carnitine
c. Acetyl CoA
d. Palmitate
Malonyl CoA
Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will
activate which of the following enzymes?
a. glycogen synthase
b. lipoprotein lipase
c. hormone sensitive lipase
d. pyruvate dehydrogenase complex
hormone sensitive lipase
, ATP can be generated by many metabolic pathways in the body. Which of the
following processes generates the most ATP?
a. glycogenolysis
b. fatty acid β-oxidation
c. pentose phosphate pathway
d. citric acid cycle
Fatty acid β-oxidation
In liver, which of the following key inhibitory events ensures that newly
synthesized palmitoyl-CoA is not immediately oxidized?
a. Inhibition of CPT-II by acetyl-CoA
b. Inhibition of CPT-I by malonyl-CoA
c. Inhibition of CPT-I by palmitoyl-carnitine
d. Inhibition of acyl-CoA synthetase by malonyl-CoA
Inhibition of CPT-I by malonyl-CoA
Ketonuria, hyperglycemia and severe acidosis are prime diagnostic indicators of
the presentation of Type I diabetic ketoacidosis. Which of the following
compounds are "ketone bodies" that would be elevated in serum and urine of a
patient in this condition?
a. fumarate and succinate
b. pyruvate and lactate
