, PRINCIPLES OF
Human Physiology
Sixth Edition
Global Edition
CINDY L. STANFIELD
University of South Alabama
)BSMPX &OHMBOEt-POEPOt/FX:PSLt#PTUPOt4BO'SBODJTDPt5PSPOUPt4ZEOFZt%VCBJt4JOHBQPSFt)POH,POH
5PLZPt4FPVMt5BJQFJt/FX%FMIJt$BQF5PXOt4BP1BVMPt.FYJDP$JUZt.BESJEt"NTUFSEBNt.VOJDIt1BSJTt.JMBO
,Senior Acquisitions Editor: Kelsey Assistant Project Editor, Global Edition: Shaoni
Churchman Mukherjee
Program Manager: Chriscelle Palaganas Manager, Media Production, Global
Project Manager: Chakira Lane Edition: Vikram Kumar
Director of Development: Barbara Yien Senior Manufacturing Controller, Production,
Editorial Assistant: Ashley Williams Global Edition: Trudy Kimber
Content Producer: Joe Mochnick Managing Editor: Angel Chavez
Text and Photo Permissions Project Manager: Design Manager: Marilyn Perry
Tim Nicholls Text Designer: Emily Friel
Program Management Team Lead: Mike Early Marketing Manager: Allison Rona
Project Management Team Lead: Nancy Tabor Senior Manufacturing Buyer: Stacey
Assistant Acquisitions Editor, Global Edition: Weinberger
Aditee Agarwal
Cover Photo Credit: Pan Xunbin
Credits and acknowledgments for materials borrowed from other sources and reproduced, with permission, in this
textbook appear on the appropriate page within the text in the case of art or text material and on p. 758 in the case of
photos.
Pearson Education Limited
Edinburgh Gate
Harlow
Essex CM20 2JE
England
and Associated Companies throughout the world
Visit us on the World Wide Web at: www.pearsonglobaleditions.com
© Pearson Education Limited 2017
The rights of Cindy L. Stanfield to be identified as the author of this work have been asserted by her in accordance
with the Copyright, Designs and Patents Act 1988.
Authorized adaptation from the United States edition, entitled Principles of Human Physiology, 6th edition,
ISBN 978-0-134-16980-4, by Cindy L. Stanfield, published by Pearson Education © 2017.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in
any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without either the prior
written permission of the publisher or a license permitting restricted copying in the United Kingdom issued by the
Copyright Licensing Agency Ltd, Saffron House, 6–10 Kirby Street, London EC 1N 8TS.
All trademarks used herein are the property of their respective owners. The use of any trademark in this text does not
vest in the author or publisher any trademark ownership rights in such trademarks, nor does the use of such trade-
marks imply any affiliation with or endorsement of this book by such owners.
MasteringA&P®, A&PFlixTM, Interactive Physiology®, and PhysioExTM are trademarks, in the U.S. and/or other coun-
tries, of Pearson Education, Inc. or its affiliates.
ISBN 10: 1-292-15648-1
ISBN 13: 978-1-292-15648-4
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
10 9 8 7 6 5 4 3 2 1
Typeset by Integra Software Services, Inc.
Printed and bound by Vivar in Malaysia
, VE IT!
SOL
Solve It Tutorials
4 How Can Membrane Transport Changes Lead to a Heart Attack?
11 Why Does Mio Keep Falling Down? Part 4
13 Why Does Mio Keep Falling Down? Part 2
14 Why Does Mio Keep Falling Down? Part 1
15 Why Is Marcus Forming Blood Clots and What Problems Can They Cause?
19 Why Does Mio Keep Falling Down? Part 3
19 What Is Causing Episodes of Muscle Weakness in this Patient?*
19 The Car Accident: How Is Breathing Related to Acid-Base Balance?*
21 How Are Insulin Pathways Involved in Diabetes Pathogenesis and Treatment?
22 Does Sex Determination Have Only Two Possible Outcomes: Male or Female?*
24 How Does Diabetes Pathogenesis Progress?
*These Solve It tutorials are not printed in the textbook, but are assignable in MasteringA&P.
Human Physiology
Sixth Edition
Global Edition
CINDY L. STANFIELD
University of South Alabama
)BSMPX &OHMBOEt-POEPOt/FX:PSLt#PTUPOt4BO'SBODJTDPt5PSPOUPt4ZEOFZt%VCBJt4JOHBQPSFt)POH,POH
5PLZPt4FPVMt5BJQFJt/FX%FMIJt$BQF5PXOt4BP1BVMPt.FYJDP$JUZt.BESJEt"NTUFSEBNt.VOJDIt1BSJTt.JMBO
,Senior Acquisitions Editor: Kelsey Assistant Project Editor, Global Edition: Shaoni
Churchman Mukherjee
Program Manager: Chriscelle Palaganas Manager, Media Production, Global
Project Manager: Chakira Lane Edition: Vikram Kumar
Director of Development: Barbara Yien Senior Manufacturing Controller, Production,
Editorial Assistant: Ashley Williams Global Edition: Trudy Kimber
Content Producer: Joe Mochnick Managing Editor: Angel Chavez
Text and Photo Permissions Project Manager: Design Manager: Marilyn Perry
Tim Nicholls Text Designer: Emily Friel
Program Management Team Lead: Mike Early Marketing Manager: Allison Rona
Project Management Team Lead: Nancy Tabor Senior Manufacturing Buyer: Stacey
Assistant Acquisitions Editor, Global Edition: Weinberger
Aditee Agarwal
Cover Photo Credit: Pan Xunbin
Credits and acknowledgments for materials borrowed from other sources and reproduced, with permission, in this
textbook appear on the appropriate page within the text in the case of art or text material and on p. 758 in the case of
photos.
Pearson Education Limited
Edinburgh Gate
Harlow
Essex CM20 2JE
England
and Associated Companies throughout the world
Visit us on the World Wide Web at: www.pearsonglobaleditions.com
© Pearson Education Limited 2017
The rights of Cindy L. Stanfield to be identified as the author of this work have been asserted by her in accordance
with the Copyright, Designs and Patents Act 1988.
Authorized adaptation from the United States edition, entitled Principles of Human Physiology, 6th edition,
ISBN 978-0-134-16980-4, by Cindy L. Stanfield, published by Pearson Education © 2017.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in
any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without either the prior
written permission of the publisher or a license permitting restricted copying in the United Kingdom issued by the
Copyright Licensing Agency Ltd, Saffron House, 6–10 Kirby Street, London EC 1N 8TS.
All trademarks used herein are the property of their respective owners. The use of any trademark in this text does not
vest in the author or publisher any trademark ownership rights in such trademarks, nor does the use of such trade-
marks imply any affiliation with or endorsement of this book by such owners.
MasteringA&P®, A&PFlixTM, Interactive Physiology®, and PhysioExTM are trademarks, in the U.S. and/or other coun-
tries, of Pearson Education, Inc. or its affiliates.
ISBN 10: 1-292-15648-1
ISBN 13: 978-1-292-15648-4
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
10 9 8 7 6 5 4 3 2 1
Typeset by Integra Software Services, Inc.
Printed and bound by Vivar in Malaysia
, VE IT!
SOL
Solve It Tutorials
4 How Can Membrane Transport Changes Lead to a Heart Attack?
11 Why Does Mio Keep Falling Down? Part 4
13 Why Does Mio Keep Falling Down? Part 2
14 Why Does Mio Keep Falling Down? Part 1
15 Why Is Marcus Forming Blood Clots and What Problems Can They Cause?
19 Why Does Mio Keep Falling Down? Part 3
19 What Is Causing Episodes of Muscle Weakness in this Patient?*
19 The Car Accident: How Is Breathing Related to Acid-Base Balance?*
21 How Are Insulin Pathways Involved in Diabetes Pathogenesis and Treatment?
22 Does Sex Determination Have Only Two Possible Outcomes: Male or Female?*
24 How Does Diabetes Pathogenesis Progress?
*These Solve It tutorials are not printed in the textbook, but are assignable in MasteringA&P.
