Student Worksheet
OVERVIEW
This worksheet complements the Central Dogma and Genetic Medicine Click & Learn.
PROCEDURE
As you proceed through the Click & Learn, follow the instructions below and answer the questions in the spaces
provided.
1. Let’s review! The central dogma of molecular biology refers to the process of gene expression. Write the
definition of gene expression in your own words.
The phenotype of the gene/the characteristic that is shown.
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2. Click on the “Central Dogma” menu tab at the top of the screen.
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The table below outlines the steps in eukaryotic gene expression. Click on each tab or scroll through the page
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and briefly summarize each step below.
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Gene rs e
Molecules Involved
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Summary
Expression What molecules and proteins
What happens during this step?
Steps are involved in this step?
RNA Polymerase, DNA, RNA Polymerase converts information from a
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RNA, Exon and Intron section of the DNA into a complementary
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Transcription sequence with the tRNA.
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Spliceosome, Inron, Exon The spliceosome cuts up introns and splices
together exons to create mRNA
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RNA Splicing
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mRNA The mRNA is sent out the nucleus and into the
cytoplasm
is
mRNA
Transport
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mRNA, tRNA, Ribosome, Amino acids are put together in a chain by the
Polypeptide ribosome once it reads the code from the tRNA
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Translation that it recieved from the mRNA.
Polypeptide WHen the chain is complete the polypeptide will
Protein fold into a 3D protein and do a specific kind of
Processing function. This is done in the Golgi or in the
cytoplasm.
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Genetics Published January 2018
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