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MRO Practice Exam – Actual Questions with Verified Answers & Rationales 2026/2027 | Assured Pass | Instant Download

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This document contains a complete MRO (Medical Review Officer) practice exam with verified answers and rationales, covering key topics such as EAP components, DOT post-accident testing, custody and control form compliance, split specimen analysis, and regulatory requirements. Updated for 2026/2027, this resource is ideal for exam preparation, certification review, and mastering MRO policies and DOT regulations.

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MRO PRACTICE EXAM ACTUAL QUESTIONS
AND ANSWERS - LATEST AND COMPLETE
UPDATE WITH VERIFIED SOLUTIONS –
ASSURED PASS WITH INSTANT DOWNLOAD
PDF.
All of the following are usual components of an EAP program EXCEPT:
A. Employee education
B. Supervisor training
C. Clinical assessment
D. Information and referral
E. Pre-employment drug testing - ANSWER: E


A DOT mandated post-accident test was conducted at a hospital emergency room,
and the nurse mistakenly used a non-DOT custody and control form. The specimen
was screened and confirmed positive for THC in accordance with DHHS
laboratory guidelines. The MRO has interviewed the donor and there is no
alternate medical explanation for the THC. In review of the custody and control
form, the only flaw noted by the MRO is that the non-DOT form was used. What
should the MRO do?
A. Require another specimen collection
B. Report as negative
C. Obtain a written statement from the nurse and report as positive
D. Report as cancelled
E. Report as positive - ANSWER: C


A driver's DOT drug test is positive. To ensure the right to have the split specimen
analyzed, the donor must request the additional analysis within:

,A. 2 days
B. 3 days
C. 5 days
D. 7 days
E. There is no time limit - ANSWER: B


A split sample has reconfirmed the primary test result. The employee requests
reanalysis of the primary specimen. Under DOT regulations, the MRO should:
A. Direct a reanalysis if requested within 72 hours of the result being reported to
the donor
B. Deny the request for reanalysis
C. Order a test of the split sample only
D. Request a quantitative analysis of the split sample
E. None of these are correct - ANSWER: B


Which one of the following statements is true?
A. l-methamphetamine is metabolized to l-amphetamine.
B. d-amphetamine is metabolized to d-methamphetamine.
C. GC/MS methods cannot differentiate between d- and l- forms of
methamphetamine.
D. The presence of l-methamphetamine rules out the illicit use of
methamphetamine.
E. The presence of d-methamphetamine rules out the illicit use of
methamphetamine. - ANSWER: A


Which of the following can be a metabolite of morphine?
A. Hydromorphone

,B. Diacetylmorphine
C. Monoacetylmorphine
D. Hydrocodone
E. Normorphine - ANSWER: A and E


Which of the following is/are true of alcohol testing?
A. Industrial exposure to certain solvents may cause some interference with the
determination of alcohol ingestion
B. Ingested food will generally hasten the absorption of alcohol.
C. Assuming no post-accident consumption, a driver's blood alcohol concentration
45 minutes after an accident may overestimate his or her level at the time of the
accident.
D. Assuming no post-accident consumption, a driver's blood alcohol concentration
45 minutes after an accident may underestimate his or her level at the time of the
accident.
E. All of these are true statements - ANSWER: A, C, and D


Which of the following REQUIRE(S) an observed collection under DOT
regulations?
A. Donor admits to illicit drug use.
B. Donor presents with clinical signs consistent with opiate abuse.
C. Donor states that he or she is unable to provide urine.
D. State law permits routine observed collections, and the employer's policy
requires this action.
E. Specimen temperature is 89.5 degrees Fahrenheit. - ANSWER: E


Under DOT regulations, which of the following is/are true?
A. If the primary specimen is negative, the lab may dispose of the split sample.

, B. If the primary specimen is confirmed positive, the split specimen must be
preserved for at least one year.
C. If a split test is requested, the MRO must obtain and ship the split sample to
another DHHS Certified lab.
D. If the drug(s) is(are) not detected in the split sample, and validity testing is
negative, then the test is canceled. - ANSWER: A, B, and D


2. Which of the following drug tests is not required for federal employees under
the federal Drug-Free Workplace Program?


A.Preplacement
B.Post-accident
C.Return to duty
D.Unreasonable suspicion
E.Random - ANSWER: D
SAMHSA's Drug Free Workplace Program specifies "Reasonable Suspicion" as
one of the types of drug testing. This is found on the federal Custody and Control
Form. The incorrect answer was unreasonable suspicion.


3. Which of the following is the "weakest link" in drug testing, i.e., generally
produces the most frequent errors?
A.Specimen collection
B.Laboratory testing
C.MRO review - ANSWER: A
Among drug testing personnel, there are far more specimen collectors than
laboratory staff or MROs. Collectors receive the least amount of training, are paid
the lowest wages, and have the highest job turnover.
Quality reviews show that a substantially larger number of errors occur in
collection and properly completing the Custody and Control Form.

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