Description of cancer Uncontrolled and unregulated growth of cells
Abnormal cell growth and defective cell
differentiation
Know health promotion and cancer -Reversing activity of promoters
prevention -Reduce or avoid exposure to carcinogens
-Eat balanced diet, avoid alcohol
-Exercise, healthy weight
-Eliminate stressors
-Regular physical exam
-Cancer screening, self-exams
-Chemoprevention, immunizations
Screening prevention: ATI p. 569 -Mammogram – every year for women >40
- Papanicolaou test, colonoscopy, -Breast exam – every year for women >40
mammogram, fecal occult blood, PSA, -Colonoscopy – starting at 50 and every 10 yr
m
CEA -Fecal occult – every year for all adults
er as
- Papanicolaou – pap smear, every 3 yrs for women
co
>21
eH w
-PSA and CEA – blood test, checks biomarkers in
o.
embryonic cells
rs e
ou urc
Etiology, pathophysiology, risk factors of -Age, immune system, tissue trauma, race
cancer (Caucasian), genetics, exposure to chemicals, alcohol
and tobacco, viruses, diet, sun, UV, radiation, sexual
o
lifestyle, poverty, obesity, GERD, chronic disease, air
pollution
aC s
vi y re
Staging of Cancer: clinical staging 1 – evidence of tumor, limited to tissue of origin
(Stage I to Stage IV) and prognosis 2 – bigger tumor, limited local spread
3 – extensive local and regional spread, in lymph
ed d
nodes
ar stu
4 – metastasis
Seven warning signs of cancer: ATI p. 575 C – change in bowel or bladder habits
- acronym CAUTION A – a sore that doesn’t heal
is
U – unusual bleeding or discharge
Th
T – thickening or lump
I – indigestion or difficulty swallowing
O – obvious change in warts or moles
N – nagging cough or hoarseness
sh
chemotherapy: define Cytotoxic meds that damage a cell’s DNA or destroy
rapidly dividing cells
Complications/adverse effects of Myelosuppression (decreased bone marrow activity)
chemotherapy inhibited bone marrow production of WBCs, RBCs
and platelets
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