Vit B12 interventions
monitor potassium and for potassium deficiency
Vit B12 admin
PO, subcut, IM, intranasal
Schilling test to confirm gastric absorption
give PO w/ food
give intranasal 1 hr before/after eating hot foods
baseline: B12, H/H, RBCs, reticulocytes
foods high in B12: dairy, enriched cereal, egg yolk, some
seafood
Vit B12 education
report:
muscle weakness
nausea
palpitations
paresthesia
Vit B12 c/p
sensitivity
hereditary optic nerve atrophy
renal dysfunction
concurrent infections
CVD
pulmonary disease
,other anemias
concurrent folic acid use
Vit B12 interactions
folic acid can mask B12 deficiency
chloramphenicol: dec effectiveness
Alcohol, cimetidine, colchicine, and aminosalicylic acid: dec
absorption of oral forms
Vit C: alters stability of oral forms
alteplase MOA
converts plasminogen to plasmin
alteplase therapeutic use
acute MI
DVT
PE
CVA
re-establish patency of CVADs
alteplase adverse reactions
bleeding
alteplase interventions
limit injections/venipuncture
use pressure dressings
monitor VS, aPTT, PT, INR, H/H
monitor for intracranial bleeding (LOC, HA, unilateral
weakness)
d/c for severe bleeding
, alteplase admin
IV
2 hr for MI
3-4.5 hr for CVA
baseline: VS, platelets, H/H, aPTT, PT, INR, fibrinogen
admin heparin/aspirin after thrombolytic therapy
alteplase education
report:
bleeding
HA
weakness
alteplase c/p
prior hemorrhagic CVA
cerebral vascular lesions
aortic dissection
active internal bleeding
sig. head/facial trauma in last 3 mo
acute pericarditis
brain tumor
severe HTN
ischemic CVA in last 6 mo
major surgery in last 2-4 wks
active peptic ulcer disease
alteplase interactions
NSAIDs, heparin, warfarin, thrombolytics, antiplatelets: inc
bleeding risk