Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
TEST BANK
Concepts of Genetics
William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
12th Edition
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
Table of Contents
Part One–Genes, Chromosomes, and Heredity
1 Introduction to Genetics
2 Mitosis and Meiosis
3 Mendelian Genetics
4 Extensions of Mendelian Genetics
5 Chromosome Mapping in Eukaryotes
6 Genetic Analysis and Mapping in Bacteria and Bacteriophages
7 Sex Determination and Sex Chromosomes
8 Chromosome Mutations: Variation in Number and Arrangement
9 Extranuclear Inheritance
Part Two–DNA: Structure, Replication, and Organization
10 DNA Structure and Analysis
11 DNA Replication and Recombination
12 DNA Organization in Chromosomes
Part Three–Gene Expression and Its Regulation
13 The Genetic Code and Transcription
14 Translation and Proteins
15 Gene Mutation, DNA Repair, and Transposition
16 Regulation of Gene Expression in Bacteria
17 Transcriptional Regulation in Eukaryotes
18 Post-transcriptional Regulation in Eukaryotes
19 Epigenetic Regulation in Eukaryotes
Part Four–Genomics
20 Recombinant DNA Technology
21 Genomic Analysis
22 Applications of Genetic Engineering and Biotechnology
Part Five–Genetics of Organisms and Populations
23 Developmental Genetics
24 Cancer Genetics
25 Quantitative Genetics and Multifactorial Traits
26 Population and Evolutionary Genetics
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
Chapter 1 Introduction to Genetics
1) In the 1600s, William Harvey studied reproduction and development. What is the term given
to the theory that states that an organism develops from the fertilized egg by a succession of
developmental events that lead to an adult?
A) preformation
B) sequential pattern formation
C) equational transformation
D) transduction
E) epigenesis
Answer: E
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
2) What is the term given to the theory that states that the fertilized egg contains a complete
miniature adult?
A) preformation
B) transduction
C) transformation
D) conjugation
E) cell theory
Answer: A
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
3) What is the term given to the theory that put forth the idea that living organisms could arise by
incubating nonliving components?
A) spontaneous generation
B) natural selection
C) evolution
D) preformation
E) collective combination
Answer: A
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
4) What is a homunculus?
A) a large cyst or growth on a plant due to viral infection
B) a sperm or egg containing a miniature adult, perfect in size and proportion
C) the intermediate stage of the DNA after CRISPR-Cas treatment
D) when the mitochondrion grows in size before splitting into two via fission
E) during development sometimes a growing individual's cell can become mutated and one part
of the child has different characteristics than the other
Answer: B
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
1
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
5) Who, along with Alfred Wallace, formulated the theory of natural selection?
A) Gregor Mendel
B) William Harvey
C) Louis Pasteur
D) Charles Darwin
E) James Watson
Answer: D
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
6) Who was the Augustinian monk that conducted a decade of experiments on the garden pea,
eventually showing that traits are passed from parents to offspring in predictable ways?
A) Francis Crick
B) Alfred Wallace
C) Hippocrates
D) Aristotle
E) Gregor Mendel
Answer: E
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
7) In many species, there are two representatives of each chromosome. In such species, the
characteristic number of chromosomes is called the ________ number. It is usually symbolized
as ________.
A) haploid; n
B) haploid; 2n
C) diploid; 2n
D) diploid; n
E) monoploid; n
Answer: C
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
8) Genetics is the study of ________.
A) inheritance and variation
B) mutation and recession
C) transcription and translation
D) diploid and haploid
E) replication and recombination
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
2
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
9) Early in the twentieth century, Walter Sutton and Theodor Boveri noted that the behavior of
chromosomes during meiosis is identical to the behavior of genes during gamete formation. They
proposed that genes are carried on chromosomes, which led to the basis of the ________.
A) Chromosome Theory of Inheritance
B) Law of Segregation
C) Law of Independent Assortment
D) First Law of Thermodynamics
E) Chromosomal Maintenance Theory
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
10) What is a mutation?
A) an inherited change in a DNA sequence
B) the source of all genetic variation
C) a change in DNA that leads to death
D) an inherited change in DNA sequences that is the source of all genetic variation
E) an inherited changed in DNA sequence that is always bad for an organism
Answer: D
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
11) Which of the following is TRUE about alleles?
A) An allele is a variant form of a gene.
B) Alleles come in two forms, the good form and the bad form.
C) Individuals carry both forms of each allele.
D) The phenotype of the individual will always indicate with certainty the alleles of the
individual.
E) An individual will only carry one version of an allele.
Answer: A
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
12) Until the mid-1940s, many scientists considered proteins to be the likely candidates for the
genetic material. Which of the following characteristics led scientist to believe DNA was NOT
the genetic material?
A) DNA is more stable than protein.
B) DNA is less abundant than protein.
C) DNA has less variation than protein.
D) Protein can fold into may shapes.
E) DNA is less abundant than protein and DNA has less variation than protein.
Answer: E
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
3
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
13) Name the individual who, while working with the garden pea in the mid-1850s,
demonstrated quantitative patterns of heredity and developed a theory involving the behavior of
hereditary factors.
A) Walter Sutton
B) Theodor Boveri
C) Barbara McClintock
D) Gregor Mendel
E) George Wallace
Answer: D
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
14) Which of the following is the subdiscipline of biology concerned with the study of heredity
and variation at the molecular, cellular, developmental, organismal, and populational levels?
A) genetics
B) cell biology
C) molecular biology
D) cytogenetics
E) biochemistry
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
15) Which of the following is an example of natural selection?
A) a bird's beak is able to effectively crack the seeds it encounters
B) human beings develop freckles from being out in the sun
C) depending on the food a turtle eats, it shell may grow faster or slower
D) sometime during human's life they break a bone and it heals
E) bacteria can be effectively killed by treatment with bleach
Answer: A
Section: 1.1
Bloom's Taxonomy: Evaluating/Creating
16) What term is used to describe the fact that different genes in an organism often provide
differences in observable features?
A) phenotype
B) genotype
C) alleles
D) natural selection
E) inheritance
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
4
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
17) Which of the following is an example of heredity?
A) Doberman pinschers and boxers have similar body shapes.
B) Both moths and birds have wings and can fly.
C) Dalmation dogs all have spots.
D) Flying squirrels have a different mechanism of flight than mosquitos.
E) Flies and molluscs both have eyes.
Answer: C
Section: 1.2
Bloom's Taxonomy: Evaluating/Creating
18) Which of the following is NOT an example of variation?
A) a child does not have her mother's hair color
B) cats can have long or short fur
C) giraffes have not been seen in an albino form
D) both monocotyledons and dicotyledons perform the dark reaction
E) lobsters can come in many colors including blue, read, and brown
Answer: D
Section: 1.2
Bloom's Taxonomy: Evaluating/Creating
19) What would happen if, during meiosis, the chromosome number was not halved before egg
and sperm formation?
A) nothing
B) in each successive generation, the offspring would double their chromosome number
C) n would become halved
D) each offspring would have different phenotypes than their parents
E) the spindle would be compromised
Answer: B
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
20) Alternative forms of a gene are called ________.
A) alleles
B) mutants
C) phenotypes
D) genotypes
E) meiotic products
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
5
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
21) The various characteristics of organisms that result from their genetic makeup are
collectively referred to as an organism's ________.
A) genotype
B) alleles
C) phenotype
D) genome
E) proteome
Answer: C
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
22) Name the substance that serves as the hereditary material in eukaryotes and prokaryotes.
A) RNA or ribonucleic acid
B) DNA or deoxyribonucleic acid
C) protein
D) lipid
E) carbohydrate
Answer: B
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
23) Which of the following contains all the others?
A) double helix
B) nucleotide
C) hydrogen bond
D) DNA strand
E) sugar
Answer: A
Section: 1.3
Bloom's Taxonomy: Applying/Analyzing
24) A fundamental property of DNA's nitrogenous bases that is necessary for the double-
stranded nature of its structure is ________.
A) complementarity
B) anti-parallel
C) ring structure
D) sugar phosphate backbone
E) deoxyribose versus ribose
Answer: A
Section: 1.3
Bloom's Taxonomy: Applying/Analyzing
6
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
25) Which of the following is the function of DNA?
A) DNA serves to hold the information for protein, lipid, and carbohydrate storage.
B) DNA is required when cells are using their ribosomes to translate a protein.
C) DNA is responsible for the storage and replication of genetic information.
D) DNA is involved in the expression of stored genetic information.
E) DNA is used structurally to hold the nucleus together.
Answer: C
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
26) Which of the following molecules serves the function to express the genetic material by
being translated to protein?
A) DNA
B) lipid
C) carbohydrate
D) RNA
E) cholesterol
Answer: D
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
27) Name the bases in DNA and their pairing specificities.
A) adenine:thymine, guanine:cytosine
B) adenine:uracil, guanine:cytosine
C) adenine:guanine, guanine:uracil
D) adenine:cytosine, guanine:uracil
E) adenine:guanine, thymine:cytosine
Answer: A
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
28) The ________ consists of a linear series of three adjacent nucleotides present in mRNA
molecules.
A) genetic code
B) Watson—Crick base pairing
C) chromosomal theory of inheritance
D) law of segregation
E) messenger RNA
Answer: A
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
7
.
TEST BANK
Concepts of Genetics
William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
12th Edition
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
Table of Contents
Part One–Genes, Chromosomes, and Heredity
1 Introduction to Genetics
2 Mitosis and Meiosis
3 Mendelian Genetics
4 Extensions of Mendelian Genetics
5 Chromosome Mapping in Eukaryotes
6 Genetic Analysis and Mapping in Bacteria and Bacteriophages
7 Sex Determination and Sex Chromosomes
8 Chromosome Mutations: Variation in Number and Arrangement
9 Extranuclear Inheritance
Part Two–DNA: Structure, Replication, and Organization
10 DNA Structure and Analysis
11 DNA Replication and Recombination
12 DNA Organization in Chromosomes
Part Three–Gene Expression and Its Regulation
13 The Genetic Code and Transcription
14 Translation and Proteins
15 Gene Mutation, DNA Repair, and Transposition
16 Regulation of Gene Expression in Bacteria
17 Transcriptional Regulation in Eukaryotes
18 Post-transcriptional Regulation in Eukaryotes
19 Epigenetic Regulation in Eukaryotes
Part Four–Genomics
20 Recombinant DNA Technology
21 Genomic Analysis
22 Applications of Genetic Engineering and Biotechnology
Part Five–Genetics of Organisms and Populations
23 Developmental Genetics
24 Cancer Genetics
25 Quantitative Genetics and Multifactorial Traits
26 Population and Evolutionary Genetics
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
Chapter 1 Introduction to Genetics
1) In the 1600s, William Harvey studied reproduction and development. What is the term given
to the theory that states that an organism develops from the fertilized egg by a succession of
developmental events that lead to an adult?
A) preformation
B) sequential pattern formation
C) equational transformation
D) transduction
E) epigenesis
Answer: E
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
2) What is the term given to the theory that states that the fertilized egg contains a complete
miniature adult?
A) preformation
B) transduction
C) transformation
D) conjugation
E) cell theory
Answer: A
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
3) What is the term given to the theory that put forth the idea that living organisms could arise by
incubating nonliving components?
A) spontaneous generation
B) natural selection
C) evolution
D) preformation
E) collective combination
Answer: A
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
4) What is a homunculus?
A) a large cyst or growth on a plant due to viral infection
B) a sperm or egg containing a miniature adult, perfect in size and proportion
C) the intermediate stage of the DNA after CRISPR-Cas treatment
D) when the mitochondrion grows in size before splitting into two via fission
E) during development sometimes a growing individual's cell can become mutated and one part
of the child has different characteristics than the other
Answer: B
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
1
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
5) Who, along with Alfred Wallace, formulated the theory of natural selection?
A) Gregor Mendel
B) William Harvey
C) Louis Pasteur
D) Charles Darwin
E) James Watson
Answer: D
Section: 1.1
Bloom's Taxonomy: Remembering/Understanding
6) Who was the Augustinian monk that conducted a decade of experiments on the garden pea,
eventually showing that traits are passed from parents to offspring in predictable ways?
A) Francis Crick
B) Alfred Wallace
C) Hippocrates
D) Aristotle
E) Gregor Mendel
Answer: E
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
7) In many species, there are two representatives of each chromosome. In such species, the
characteristic number of chromosomes is called the ________ number. It is usually symbolized
as ________.
A) haploid; n
B) haploid; 2n
C) diploid; 2n
D) diploid; n
E) monoploid; n
Answer: C
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
8) Genetics is the study of ________.
A) inheritance and variation
B) mutation and recession
C) transcription and translation
D) diploid and haploid
E) replication and recombination
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
2
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
9) Early in the twentieth century, Walter Sutton and Theodor Boveri noted that the behavior of
chromosomes during meiosis is identical to the behavior of genes during gamete formation. They
proposed that genes are carried on chromosomes, which led to the basis of the ________.
A) Chromosome Theory of Inheritance
B) Law of Segregation
C) Law of Independent Assortment
D) First Law of Thermodynamics
E) Chromosomal Maintenance Theory
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
10) What is a mutation?
A) an inherited change in a DNA sequence
B) the source of all genetic variation
C) a change in DNA that leads to death
D) an inherited change in DNA sequences that is the source of all genetic variation
E) an inherited changed in DNA sequence that is always bad for an organism
Answer: D
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
11) Which of the following is TRUE about alleles?
A) An allele is a variant form of a gene.
B) Alleles come in two forms, the good form and the bad form.
C) Individuals carry both forms of each allele.
D) The phenotype of the individual will always indicate with certainty the alleles of the
individual.
E) An individual will only carry one version of an allele.
Answer: A
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
12) Until the mid-1940s, many scientists considered proteins to be the likely candidates for the
genetic material. Which of the following characteristics led scientist to believe DNA was NOT
the genetic material?
A) DNA is more stable than protein.
B) DNA is less abundant than protein.
C) DNA has less variation than protein.
D) Protein can fold into may shapes.
E) DNA is less abundant than protein and DNA has less variation than protein.
Answer: E
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
3
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
13) Name the individual who, while working with the garden pea in the mid-1850s,
demonstrated quantitative patterns of heredity and developed a theory involving the behavior of
hereditary factors.
A) Walter Sutton
B) Theodor Boveri
C) Barbara McClintock
D) Gregor Mendel
E) George Wallace
Answer: D
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
14) Which of the following is the subdiscipline of biology concerned with the study of heredity
and variation at the molecular, cellular, developmental, organismal, and populational levels?
A) genetics
B) cell biology
C) molecular biology
D) cytogenetics
E) biochemistry
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
15) Which of the following is an example of natural selection?
A) a bird's beak is able to effectively crack the seeds it encounters
B) human beings develop freckles from being out in the sun
C) depending on the food a turtle eats, it shell may grow faster or slower
D) sometime during human's life they break a bone and it heals
E) bacteria can be effectively killed by treatment with bleach
Answer: A
Section: 1.1
Bloom's Taxonomy: Evaluating/Creating
16) What term is used to describe the fact that different genes in an organism often provide
differences in observable features?
A) phenotype
B) genotype
C) alleles
D) natural selection
E) inheritance
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
4
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
17) Which of the following is an example of heredity?
A) Doberman pinschers and boxers have similar body shapes.
B) Both moths and birds have wings and can fly.
C) Dalmation dogs all have spots.
D) Flying squirrels have a different mechanism of flight than mosquitos.
E) Flies and molluscs both have eyes.
Answer: C
Section: 1.2
Bloom's Taxonomy: Evaluating/Creating
18) Which of the following is NOT an example of variation?
A) a child does not have her mother's hair color
B) cats can have long or short fur
C) giraffes have not been seen in an albino form
D) both monocotyledons and dicotyledons perform the dark reaction
E) lobsters can come in many colors including blue, read, and brown
Answer: D
Section: 1.2
Bloom's Taxonomy: Evaluating/Creating
19) What would happen if, during meiosis, the chromosome number was not halved before egg
and sperm formation?
A) nothing
B) in each successive generation, the offspring would double their chromosome number
C) n would become halved
D) each offspring would have different phenotypes than their parents
E) the spindle would be compromised
Answer: B
Section: 1.2
Bloom's Taxonomy: Applying/Analyzing
20) Alternative forms of a gene are called ________.
A) alleles
B) mutants
C) phenotypes
D) genotypes
E) meiotic products
Answer: A
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
5
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
21) The various characteristics of organisms that result from their genetic makeup are
collectively referred to as an organism's ________.
A) genotype
B) alleles
C) phenotype
D) genome
E) proteome
Answer: C
Section: 1.2
Bloom's Taxonomy: Remembering/Understanding
22) Name the substance that serves as the hereditary material in eukaryotes and prokaryotes.
A) RNA or ribonucleic acid
B) DNA or deoxyribonucleic acid
C) protein
D) lipid
E) carbohydrate
Answer: B
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
23) Which of the following contains all the others?
A) double helix
B) nucleotide
C) hydrogen bond
D) DNA strand
E) sugar
Answer: A
Section: 1.3
Bloom's Taxonomy: Applying/Analyzing
24) A fundamental property of DNA's nitrogenous bases that is necessary for the double-
stranded nature of its structure is ________.
A) complementarity
B) anti-parallel
C) ring structure
D) sugar phosphate backbone
E) deoxyribose versus ribose
Answer: A
Section: 1.3
Bloom's Taxonomy: Applying/Analyzing
6
.
, Test Bank - Concepts of Genetics 12th edition (Klug, 2020)
25) Which of the following is the function of DNA?
A) DNA serves to hold the information for protein, lipid, and carbohydrate storage.
B) DNA is required when cells are using their ribosomes to translate a protein.
C) DNA is responsible for the storage and replication of genetic information.
D) DNA is involved in the expression of stored genetic information.
E) DNA is used structurally to hold the nucleus together.
Answer: C
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
26) Which of the following molecules serves the function to express the genetic material by
being translated to protein?
A) DNA
B) lipid
C) carbohydrate
D) RNA
E) cholesterol
Answer: D
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
27) Name the bases in DNA and their pairing specificities.
A) adenine:thymine, guanine:cytosine
B) adenine:uracil, guanine:cytosine
C) adenine:guanine, guanine:uracil
D) adenine:cytosine, guanine:uracil
E) adenine:guanine, thymine:cytosine
Answer: A
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
28) The ________ consists of a linear series of three adjacent nucleotides present in mRNA
molecules.
A) genetic code
B) Watson—Crick base pairing
C) chromosomal theory of inheritance
D) law of segregation
E) messenger RNA
Answer: A
Section: 1.3
Bloom's Taxonomy: Remembering/Understanding
7
.
