NR565 / NR 565 Advanced Pharmacology Fundamentals
Midterm Exam Study Guide
100% Guarantee Pass
Consist,of,300+,Questions,and,Answers
1. During,what,trimester,is,a,pregnant,woman,most,at,risk,for,adverse,drug
reactions,with,potential,long,term,consequences?
Answer
1st,trimester,(fetus,most,at, risk,d/t,rapid,growth)
,
2. What,is,BEERS,criteria?
Answer
Recommendations,of,medications,inappropriate,for, elderly,(65,and,older),,prescriber,
,
ultimately,decides
3. What,is,the,CYP450,(cytochrome,P450)
Answer
liver,enzyme,system,where,medica-
,
, tions,are,metabolized,,can,either,be,inducers,or,inhibitors,and,create,drug-
drug, interactions
1,/,21
,4. CYP450,inducers
Answer
Speed,up,metabolism,of,drugs,(drug,is,cleared,faster),,drug, has,lesser,effect,(decrease,bl
,
ood,levels,of,drug),,elevate,CYP450,enzymes
5. CYP450,inducers,pneumonic
Answer
"Bullshit,Crap,GPS,INDUCES,rage"
,
6. CYP450,inducer,drug,names
Answer
Barbituates,,St,John,wort,,Carbamazepine,,rifampin,,alcohol,,phenytoin,,griseofulvin,,
,
phenobarbital,,sulfonylureas
7. CYP450,inhibitors
Answer
inhibit,metabolism,,increase,blood,levels,of,medications
,
8. CYP450,pneumonic
Answer
"VISA,credit,card,debt,INHIBITS,spending,on,designers,like,CK,to,look,GQ"
,
2,/,21
,9. CYP450,inhibitors,drug,names
Answer
Valproate,,isoniazid,,sulfonamides,,amiodarone,,chloramphenicol,,ketoconazole,,gr
,
apefruit,juice,,quinidine
10. Physiological,changes,during,pregnancy,that,impact,pharmacodynamics, and,
pharmacokinetic,properties,of,drugs?
Answer
increase,glomerular,filtration,rate, leads,to,increase,durg,excretion
,
increase,hepatic,metabolism,decrease,t
one,and,motility,of,bowel, increase,drug,
absorption
11. Examples,of,medications,that,can,be,teratogenic
Answer
Antiepileptic,drugs,,an-
,
, timicrobials,such,as,tetracyclines,and,fluoroquinolones,,vitamin,A,in,large,doses,, some
, anticoagulants,,and,hormonal,medications,such,as,diethylstilbestrol,(DES).
12. How,is,absorption,of,intramuscular,medications,different,in,neonates?
Answer
-
,
slow,and,erratic,due,to,low,blood,flow,in,muscles,first,few,days,of,life
3,/,21
, 13. Why,is,absorption,of,medication,in,the,stomach,increased,in,infancy?
Answer
, de-, layed,gastric,emptying
14. Some,medications,that,should,be,avoided,in,the,pediatric,patient?
Answer
, glu-
, cocorticoids,,discoloration,of,developing,teeth,with,tetracyclines,,and,kernicterus, wi
th,sulfonamides,,levofloxacin,(antibiotics)
aspirin,(Severe,intoxication,from,acute,overdose)
15. what,should,be,included,in,medication,administration,patient,education?-
Answer
, dosage,size,and,timing
route,and,technique,of,administration, d
uration,of,treatment
drug,storage
nature,and,time,course,of,desired,responses,nat
ure,and,time,course,of,adverse,responses, finish,t
aking,antibiotic
16. What,are,some,things,that,put,the,elderly,patient,at,higher,risk,for,adverse, drug
4,/,21
Midterm Exam Study Guide
100% Guarantee Pass
Consist,of,300+,Questions,and,Answers
1. During,what,trimester,is,a,pregnant,woman,most,at,risk,for,adverse,drug
reactions,with,potential,long,term,consequences?
Answer
1st,trimester,(fetus,most,at, risk,d/t,rapid,growth)
,
2. What,is,BEERS,criteria?
Answer
Recommendations,of,medications,inappropriate,for, elderly,(65,and,older),,prescriber,
,
ultimately,decides
3. What,is,the,CYP450,(cytochrome,P450)
Answer
liver,enzyme,system,where,medica-
,
, tions,are,metabolized,,can,either,be,inducers,or,inhibitors,and,create,drug-
drug, interactions
1,/,21
,4. CYP450,inducers
Answer
Speed,up,metabolism,of,drugs,(drug,is,cleared,faster),,drug, has,lesser,effect,(decrease,bl
,
ood,levels,of,drug),,elevate,CYP450,enzymes
5. CYP450,inducers,pneumonic
Answer
"Bullshit,Crap,GPS,INDUCES,rage"
,
6. CYP450,inducer,drug,names
Answer
Barbituates,,St,John,wort,,Carbamazepine,,rifampin,,alcohol,,phenytoin,,griseofulvin,,
,
phenobarbital,,sulfonylureas
7. CYP450,inhibitors
Answer
inhibit,metabolism,,increase,blood,levels,of,medications
,
8. CYP450,pneumonic
Answer
"VISA,credit,card,debt,INHIBITS,spending,on,designers,like,CK,to,look,GQ"
,
2,/,21
,9. CYP450,inhibitors,drug,names
Answer
Valproate,,isoniazid,,sulfonamides,,amiodarone,,chloramphenicol,,ketoconazole,,gr
,
apefruit,juice,,quinidine
10. Physiological,changes,during,pregnancy,that,impact,pharmacodynamics, and,
pharmacokinetic,properties,of,drugs?
Answer
increase,glomerular,filtration,rate, leads,to,increase,durg,excretion
,
increase,hepatic,metabolism,decrease,t
one,and,motility,of,bowel, increase,drug,
absorption
11. Examples,of,medications,that,can,be,teratogenic
Answer
Antiepileptic,drugs,,an-
,
, timicrobials,such,as,tetracyclines,and,fluoroquinolones,,vitamin,A,in,large,doses,, some
, anticoagulants,,and,hormonal,medications,such,as,diethylstilbestrol,(DES).
12. How,is,absorption,of,intramuscular,medications,different,in,neonates?
Answer
-
,
slow,and,erratic,due,to,low,blood,flow,in,muscles,first,few,days,of,life
3,/,21
, 13. Why,is,absorption,of,medication,in,the,stomach,increased,in,infancy?
Answer
, de-, layed,gastric,emptying
14. Some,medications,that,should,be,avoided,in,the,pediatric,patient?
Answer
, glu-
, cocorticoids,,discoloration,of,developing,teeth,with,tetracyclines,,and,kernicterus, wi
th,sulfonamides,,levofloxacin,(antibiotics)
aspirin,(Severe,intoxication,from,acute,overdose)
15. what,should,be,included,in,medication,administration,patient,education?-
Answer
, dosage,size,and,timing
route,and,technique,of,administration, d
uration,of,treatment
drug,storage
nature,and,time,course,of,desired,responses,nat
ure,and,time,course,of,adverse,responses, finish,t
aking,antibiotic
16. What,are,some,things,that,put,the,elderly,patient,at,higher,risk,for,adverse, drug
4,/,21
