(Midterm Review - Advanced Pharmacology - Baylor
University) Questions With Complete Solutions
What is the first line treatment plan for Rheumatoid Arthritis?
Methotrexate, Enbrel, Humira, and Xeljanz
DMARDs (disease modifying anti-rheumatic drugs)
Methotrexate (Trexall)
Hydroxychloroquine (Plaquenil)
Leflunomide (Arava)
Sulfasalazine (Azulfidine)
Minocycline (Minocin)
Enbrel
Humira
Xeljanz
What is the first line treatment for gout?
Colchicine or Allopurinol (if patient has hx of kidney stones)
What causes gout?
An alternation in purine metabolism, the end product of which is
uric acid. This alteration results in hyperuricemia and deposits of
urate crystals in various tissues.
Mechanism of allopurinol and colchicine?
, Inhibits neutrophil activation and lowers synthesis of uric acid
What drug classes would one use for migraine prophylaxis
treatment?
beta blockers (metoprolol, propranolol)
and antidepressants (amitriptyline and venlafaxine)
What drug classes would one use for migraine acute treatment?
Analgesics: acetaminophen, aspirin, ibuprofen, naproxen and
ketorolac.
Triptans: sumatriptan, zolmitriptan, naratriptan, rizatriptan,
almotriptan, eletriptan, and frovatriptan.
Treatment option for impetigo?
Topical mupirocin ointment (bactroban) if case is mild
(classified as up to 5 lesions). Oral antibiotic cephalexin
(keflex) is indicated if the patient has more than 5 lesions, or if
the lesions worsen after 2 to 3 days.
Upper respiratory infections Treatment
An antibiotic will not help because it is viral. You can
only treat the symptoms. After about 10 days, it can turn
bacterial.
Sinusitis Treatment
Wait at least 10 days before prescribing antibiotics. If they come
back and they're still sick after 10 days, give them
amoxicillin if they've had no recent antibiotic exposure. If there
has been antibiotic exposure within the last six months, give
them Augmentin instead. Do not give macrolides or Bactrim.