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Cortex - 🧠 ANSWER ✔✔Outer portion of kidney, contains nephrons
(functional unit for urine formation)
Medulla - 🧠 ANSWER ✔✔Inner portion of kidney, contains loops of Henle,
vasa recta, and collecting ducts
Nephron - 🧠 ANSWER ✔✔Functional unit of kidney
,Initial formation of urine
2 components: filtering element capillary network (glomerulus) and tubule
Functions of the kidney - 🧠 ANSWER ✔✔-Formation of urine
-Waste product excretion
-Electrolyte regulation
-Acid-base balance
-Water balance
-BP regulation
-Calcium/phosphorous balance
-Renal clearance
-RBC production
-Vitamin D synthesis
-Prostaglandin secretion
Glomerular filtration - 🧠 ANSWER ✔✔Filtration occurs as blood flows into
glomerulus
,Tubular resorption/secretion
Antidiuretic hormone (ADH) or vasopressin - 🧠 ANSWER ✔✔Secreted by
pituitary gland d/t responses in changes in osmolality of blood
ADH can act upon kidney increasing reabsorption of water
Osmolarity - 🧠 ANSWER ✔✔Ratio of solute to water
Osmolality - 🧠 ANSWER ✔✔Number of osmoles (unit of osmotic pressure)
dissolved per kg of solution
Aldosterone - 🧠 ANSWER ✔✔Hormone synthesized and released by
adrenal cortex
Responsible for sodium volume excretion
How does the renal system regulate acid-base balance? - 🧠 ANSWER
✔✔Reabsorbs bicarbonate from urinary filtrate
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, Excretion of acid through urine
How does the renal system regulate blood pressure? - 🧠 ANSWER
✔✔Vasa recta detection and monitoring
Renin secretion
How does the renal system regulate vitamin D synthesis? - 🧠 ANSWER
✔✔Final conversion of vitamin D to active form
How does the renal system regulate RBC production? - 🧠 ANSWER
✔✔Erythropoietin stimulates bone marrow to produce RBCs
How does the renal system regulate prostaglandin secretion? - 🧠 ANSWER
✔✔Prostaglandin E and prostacyclin production (helps vasodilate)
How does the renal system regulate waste product excretion? - 🧠 ANSWER
✔✔Urea (major waste product of protein metabolism), creatinine,
phosphates, sulfates, uric acid
Glomerular filtration rate (GFR) - 🧠 ANSWER ✔✔Amount of plasma filtered
through glomeruli per unit/time (125 mL/min - 200 mL/min)