REVISED ATI PHARMACOLOGY V3 COMPREHENSIVE EXAM WITH UPDATED RATIONALES AND PRE-EMINENT SOLUTIONS

ATI PHARMACOLOGY
PROCTORED EXAM
(NGN-STYLE QUESTIONS & CASE “SCENARIO”)
Actual Qs & Ans to Pass the Exam



This ATI test contains:


 Passing Score Guarantee

 Exam has 70 PHARMACOLOGY nursing questions

 multiple-choice format (A, B, C, D) with correct answers

 structured rationales.

 incorporate Next Generation NCLEX (NGN)-style.

 Some questions feature brief “scenario” elements and rationales.

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, 1. . CASE SCENARIO (NGN-Style: Select-All-That-Apply):
A client with asthma uses a short-acting beta₂ agonist (albuterol) PRN and has just been prescribed
cromolyn (Intal). They plan to exercise regularly.

QUESTION:
What should the nurse include in the teaching about cromolyn? (Select all that apply.)

A. Take the medication 15 minutes before exercising.
B. Follow a fixed-dose schedule for long-term control.
C. Expect to lose weight while taking the medication.
D. Observe for tremors, restlessness, palpitations.
E. Do not crush or chew tablets.

• Correct Answers: A, B
• Rationale: Cromolyn is a mast cell stabilizer used for prophylaxis; it’s taken on a schedule and 15
minutes before exercise to prevent exercise-induced bronchospasm.

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2. . CASE SCENARIO:
A client with back pain from a recent injury has been prescribed tizanidine (Zanaflex). Baseline labs: AST
20 IU/L, ALT 22 IU/L.

QUESTION:
Which lab values should the nurse expect to monitor while the client is on tizanidine?

A. Serum creatinine
B. Liver enzymes
C. WBC count
D. RBC count

• Correct Answer: B. Liver enzymes
• Rationale: Tizanidine can cause hepatotoxicity, so monitoring liver enzymes (AST, ALT) is essential.

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3. . CASE SCENARIO:
A client with persistent asthma uses a beclomethasone (QVAR) inhaler daily. They ask about dietary
changes to prevent deficiencies from chronic steroid use.

QUESTION:
Which dietary supplements should the client ensure they consume to help prevent a deficiency?

A. Iron and protein
B. Calcium and vitamin D
C. Vitamin B12 and folic acid
D. Vitamins E and K

• Correct Answer: B. Calcium and Vitamin D

, • Rationale: Inhaled corticosteroids can contribute to bone loss over time; calcium and vitamin D
supplementation protects bone health.

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4. . CASE SCENARIO:
A client has used phenylephrine (Neo-Synephrine) nasal drops for 10 days to relieve nasal congestion.
Vital signs: BP 126/80 mmHg, HR 72/min, RR 18/min.

QUESTION:
For which finding should the nurse monitor the client?

A. Sedation
B. Nasal congestion (rebound)
C. Productive cough
D. Constipation

• Correct Answer: B. Nasal congestion
• Rationale: Prolonged use of topical decongestants can cause rebound nasal congestion.

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5. . CASE SCENARIO:
A client with chronic asthma is prescribed oral prednisone (Deltasone) for exacerbations. Current vitals: BP
130/82 mmHg, HR 84/min, RR 20/min, Temp 99.1°F (37.3°C).

QUESTION:
Which finding should the nurse monitor for while the client is taking oral prednisone?

A. Weight loss
B. Infection
C. Hypoglycemia
D. Angina pain

• Correct Answer: B. Infection
• Rationale: Corticosteroids can suppress the immune response, increasing infection risk.

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6. . CASE SCENARIO:
A client with newly diagnosed hypertension is prescribed hydrochlorothiazide (HCTZ) 25 mg twice daily.
They work full-time and wonder how to schedule doses.

QUESTION:
Which instruction should the nurse include?

A. “Avoid foods high in potassium.”
B. “Take the second dose by early afternoon.”
C. “Watch for ankle swelling at night.”
D. “Limit your daily fluid intake to 1.5 liters.”