NR565 / NR 565 Advanced Pharmacology Fundamentals
Midterm Exam Study Guide
100% Guarantee Pass
Consist.of.300+.Questions.and.Answers
1. During.what.trimester.is.a.pregnant.woman.most.at.risk.for.adverse.drug
reactions.with.potential.long.term.consequences?
Answer
1st.trimester.(fetus.most.at. risk.d/t.rapid.growth)
.
2. What.is.BEERS.criteria?
Answer
Recommendations.of.medications.inappropriate.for. elderly.(65.and.older),.prescriber.
.
ultimately.decides
3. What.is.the.CYP450.(cytochrome.P450)
Answer
liver.enzyme.system.where.medica-
.
. tions.are.metabolized,.can.either.be.inducers.or.inhibitors.and.create.drug-
drug. interactions
1./.21
,4. CYP450.inducers
Answer
Speed.up.metabolism.of.drugs.(drug.is.cleared.faster),.drug. has.lesser.effect.(decrease.bl
.
ood.levels.of.drug),.elevate.CYP450.enzymes
5. CYP450.inducers.pneumonic
Answer
"Bullshit.Crap.GPS.INDUCES.rage"
.
6. CYP450.inducer.drug.names
Answer
Barbituates,.St.John.wort,.Carbamazepine,.rifampin,.alcohol,.phenytoin,.griseofulvin,.
.
phenobarbital,.sulfonylureas
7. CYP450.inhibitors
Answer
inhibit.metabolism,.increase.blood.levels.of.medications
.
8. CYP450.pneumonic
Answer
"VISA.credit.card.debt.INHIBITS.spending.on.designers.like.CK.to.look.GQ"
.
2./.21
,9. CYP450.inhibitors.drug.names
Answer
Valproate,.isoniazid,.sulfonamides,.amiodarone,.chloramphenicol,.ketoconazole,.gr
.
apefruit.juice,.quinidine
10. Physiological.changes.during.pregnancy.that.impact.pharmacodynamics. and.
pharmacokinetic.properties.of.drugs?
Answer
increase.glomerular.filtration.rate. leads.to.increase.durg.excretion
.
increase.hepatic.metabolism.decrease.t
one.and.motility.of.bowel. increase.drug.
absorption
11. Examples.of.medications.that.can.be.teratogenic
Answer
Antiepileptic.drugs,.an-
.
. timicrobials.such.as.tetracyclines.and.fluoroquinolones,.vitamin.A.in.large.doses,. some
. anticoagulants,.and.hormonal.medications.such.as.diethylstilbestrol.(DES).
12. How.is.absorption.of.intramuscular.medications.different.in.neonates?
Answer
-
.
slow.and.erratic.due.to.low.blood.flow.in.muscles.first.few.days.of.life
3./.21
, 13. Why.is.absorption.of.medication.in.the.stomach.increased.in.infancy?
Answer
. de-. layed.gastric.emptying
14. Some.medications.that.should.be.avoided.in.the.pediatric.patient?
Answer
. glu-
. cocorticoids,.discoloration.of.developing.teeth.with.tetracyclines,.and.kernicterus. wi
th.sulfonamides,.levofloxacin.(antibiotics)
aspirin.(Severe.intoxication.from.acute.overdose)
15. what.should.be.included.in.medication.administration.patient.education?-
Answer
. dosage.size.and.timing
route.and.technique.of.administration. d
uration.of.treatment
drug.storage
nature.and.time.course.of.desired.responses.nat
ure.and.time.course.of.adverse.responses. finish.t
aking.antibiotic
16. What.are.some.things.that.put.the.elderly.patient.at.higher.risk.for.adverse. drug
4./.21
Midterm Exam Study Guide
100% Guarantee Pass
Consist.of.300+.Questions.and.Answers
1. During.what.trimester.is.a.pregnant.woman.most.at.risk.for.adverse.drug
reactions.with.potential.long.term.consequences?
Answer
1st.trimester.(fetus.most.at. risk.d/t.rapid.growth)
.
2. What.is.BEERS.criteria?
Answer
Recommendations.of.medications.inappropriate.for. elderly.(65.and.older),.prescriber.
.
ultimately.decides
3. What.is.the.CYP450.(cytochrome.P450)
Answer
liver.enzyme.system.where.medica-
.
. tions.are.metabolized,.can.either.be.inducers.or.inhibitors.and.create.drug-
drug. interactions
1./.21
,4. CYP450.inducers
Answer
Speed.up.metabolism.of.drugs.(drug.is.cleared.faster),.drug. has.lesser.effect.(decrease.bl
.
ood.levels.of.drug),.elevate.CYP450.enzymes
5. CYP450.inducers.pneumonic
Answer
"Bullshit.Crap.GPS.INDUCES.rage"
.
6. CYP450.inducer.drug.names
Answer
Barbituates,.St.John.wort,.Carbamazepine,.rifampin,.alcohol,.phenytoin,.griseofulvin,.
.
phenobarbital,.sulfonylureas
7. CYP450.inhibitors
Answer
inhibit.metabolism,.increase.blood.levels.of.medications
.
8. CYP450.pneumonic
Answer
"VISA.credit.card.debt.INHIBITS.spending.on.designers.like.CK.to.look.GQ"
.
2./.21
,9. CYP450.inhibitors.drug.names
Answer
Valproate,.isoniazid,.sulfonamides,.amiodarone,.chloramphenicol,.ketoconazole,.gr
.
apefruit.juice,.quinidine
10. Physiological.changes.during.pregnancy.that.impact.pharmacodynamics. and.
pharmacokinetic.properties.of.drugs?
Answer
increase.glomerular.filtration.rate. leads.to.increase.durg.excretion
.
increase.hepatic.metabolism.decrease.t
one.and.motility.of.bowel. increase.drug.
absorption
11. Examples.of.medications.that.can.be.teratogenic
Answer
Antiepileptic.drugs,.an-
.
. timicrobials.such.as.tetracyclines.and.fluoroquinolones,.vitamin.A.in.large.doses,. some
. anticoagulants,.and.hormonal.medications.such.as.diethylstilbestrol.(DES).
12. How.is.absorption.of.intramuscular.medications.different.in.neonates?
Answer
-
.
slow.and.erratic.due.to.low.blood.flow.in.muscles.first.few.days.of.life
3./.21
, 13. Why.is.absorption.of.medication.in.the.stomach.increased.in.infancy?
Answer
. de-. layed.gastric.emptying
14. Some.medications.that.should.be.avoided.in.the.pediatric.patient?
Answer
. glu-
. cocorticoids,.discoloration.of.developing.teeth.with.tetracyclines,.and.kernicterus. wi
th.sulfonamides,.levofloxacin.(antibiotics)
aspirin.(Severe.intoxication.from.acute.overdose)
15. what.should.be.included.in.medication.administration.patient.education?-
Answer
. dosage.size.and.timing
route.and.technique.of.administration. d
uration.of.treatment
drug.storage
nature.and.time.course.of.desired.responses.nat
ure.and.time.course.of.adverse.responses. finish.t
aking.antibiotic
16. What.are.some.things.that.put.the.elderly.patient.at.higher.risk.for.adverse. drug
4./.21
