CMN 572 UNIT 1 EXAM SCRIPT 2026 FULL
QUESTIONS AND CORRECT ANSWERS STUDY
GUIDE
◉ What is the etiologic agent in syphillis? Answer: treponema
pallidum
◉ At what stages is syphillis most contagious? Answer: primary and
secondary stages
◉ What virus is transplanted transplacentally from mother to fetus?
Answer: syphillis
◉ What develops at the site of inoculation with syphillis? Answer:
Chancre
◉ What are the characteristics of a chancre? Answer: Progresses
from macule to papule to ulcer;
Typically painless, indurated, and has a clean base;
Highly infectious;
Heals spontaneously within 3 to 6 weeks; and
Multiple lesions can occur
,◉ What are classic characteristics of regional lymphadenopathy in
syphillis? Answer: rubbery, painless, and bilateral
◉ What type of lesions are most common in secondary syphillis?
Answer: mucopurulent lesions
◉ What are characteristics of secondary syphillis? Answer: Rash
(75%-100%)
Lymphadenopathy (50%-86%)
Malaise
Mucous patches (6%-30%)
Condylomata lata (10%-20%)
Alopecia (5%)
Liver and kidney involvement can occur
Splenomegaly is occasionally present
◉ At what stage are serologic titers usually the highest in syphillis?
Answer: during secondary syphillis
◉ What are the 2 types of tests used to detect syphillis? Answer:
treponemal and nontreponemal
, ◉ What is the primary tx of choice for primary, secondary, and early
latent syphillis? What can be used for pcn allergic patients? Answer:
Benzathine PCN 2.4 mill units x 1 IM
For pcn allergic patient use tetracycline and doxycycline
◉ What type of reaction should patients be warned about when tx
syphillis with pcn? Answer: Jarisch-herxheimer (Fever, malaise,
nausea/vomiting; may be associated with chills and exacerbation of
secondary rash)
Don't confuse with pcn allergy
◉ All patients who have syphillis should be tested for what? Answer:
HIV
◉ When should sex partners of patients with syphillis be treated?
Answer: If sexual contact within 90 days
◉ When should women be screened for syphillis? Answer: at first
prenatal visit. In high prevalence areas screen twice at during the
third trimester, at 28 weeks and at delivery
◉ Any woman who delivers a stillborn after 20 weeks should be
screened for what? Answer: syphillis
QUESTIONS AND CORRECT ANSWERS STUDY
GUIDE
◉ What is the etiologic agent in syphillis? Answer: treponema
pallidum
◉ At what stages is syphillis most contagious? Answer: primary and
secondary stages
◉ What virus is transplanted transplacentally from mother to fetus?
Answer: syphillis
◉ What develops at the site of inoculation with syphillis? Answer:
Chancre
◉ What are the characteristics of a chancre? Answer: Progresses
from macule to papule to ulcer;
Typically painless, indurated, and has a clean base;
Highly infectious;
Heals spontaneously within 3 to 6 weeks; and
Multiple lesions can occur
,◉ What are classic characteristics of regional lymphadenopathy in
syphillis? Answer: rubbery, painless, and bilateral
◉ What type of lesions are most common in secondary syphillis?
Answer: mucopurulent lesions
◉ What are characteristics of secondary syphillis? Answer: Rash
(75%-100%)
Lymphadenopathy (50%-86%)
Malaise
Mucous patches (6%-30%)
Condylomata lata (10%-20%)
Alopecia (5%)
Liver and kidney involvement can occur
Splenomegaly is occasionally present
◉ At what stage are serologic titers usually the highest in syphillis?
Answer: during secondary syphillis
◉ What are the 2 types of tests used to detect syphillis? Answer:
treponemal and nontreponemal
, ◉ What is the primary tx of choice for primary, secondary, and early
latent syphillis? What can be used for pcn allergic patients? Answer:
Benzathine PCN 2.4 mill units x 1 IM
For pcn allergic patient use tetracycline and doxycycline
◉ What type of reaction should patients be warned about when tx
syphillis with pcn? Answer: Jarisch-herxheimer (Fever, malaise,
nausea/vomiting; may be associated with chills and exacerbation of
secondary rash)
Don't confuse with pcn allergy
◉ All patients who have syphillis should be tested for what? Answer:
HIV
◉ When should sex partners of patients with syphillis be treated?
Answer: If sexual contact within 90 days
◉ When should women be screened for syphillis? Answer: at first
prenatal visit. In high prevalence areas screen twice at during the
third trimester, at 28 weeks and at delivery
◉ Any woman who delivers a stillborn after 20 weeks should be
screened for what? Answer: syphillis
