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Clinical manifestations of lung cancer Ans✓✓✓The major presenting
complaints of lung cancer include cough, hemoptysis (blood in sputum),
wheeze, stridor, chest pain, and dyspnea; Patients may also complain of
weight loss, excessive fatigue, and weakness. Hoarseness may be a sign
if the tumor compresses the recurrent laryngeal nerve.
Small cell lung cancer and incorrect pneumonia diagnosis
Ans✓✓✓Tumor may cause obstructive accumulation of secretions,
productive cough, which leads to incorrect diagnosis of pneumonia.
Lung cancer may be incidental finding on routine chest x-ray.
Paraneoplastic syndrome symptoms may lead to diagnosis. 'Pneumonia'
treatment not working, take biopsy, reevaluate. Patients can present
without symptoms.
Paraneoplastic syndrome clinical manifestations Ans✓✓✓unexpected
physiological changes found within the body; ex: ACTH-like hormone,
resembles MSH (melanocyte-stimulating hormone), patient has tanned
appearance
Clinical manifestations of lymphoma (first sign) Ans✓✓✓The first sign
of lymphoma is often a painless, enlarged lymph node in the neck, under
an arm, or in the groin.
What signs/symptoms may occur if an enlarged lymph node is pressing
against a vein or lymphatic vessel? Ans✓✓✓The enlarged lymph node
, sometimes causes other symptoms by pressing against a vein or
lymphatic vessel (swelling of an arm or leg).
Describe the signs/symptoms that indicate an enlarged lymph node is
pressing against a nerve? Ans✓✓✓Pain, numbness, tingling
Indicate signs/symptoms that indicate an enlarged lymph node is
pressing against the stomach Ans✓✓✓early feeling of fullness
Clinical manifestations of lymphoma Ans✓✓✓painless and enlarged
lymph node, splenomegaly, hepatomegaly, abdominal pain/discomfort,
nausea, vomiting, fever, chills, unexplained weight loss, headache,
seizure, vision impairment, facial numbness, weakness, behavioral
changes
Etiology of NHL Ans✓✓✓Chromosomal translocations are the genetic
hallmark of lymphomas. A common translocation in NHL is the
translocation of genes at 14q32 and 18q21, present in 85% of follicular
lymphomas
Etiology of HL Ans✓✓✓The cause of HL is unknown, but EBV has
been found in malignant B lymphocytes. Also, persons who are
immunosuppressed have a higher risk of HL. Exposure to carcinogens,
viruses, and genetic and immune mechanisms have been proposed as
etiologies, but none have been proven