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1. Toxic to the kidneys
Correct Answer: Nephrotoxic
2. Toxic to the ears
Correct Answer: Ototoxic
3. A drug’s strength and ability to produce the desired effect
Correct Answer: Potency
4. A drug taken with another drug so both enhance the effect
Correct Answer: Agonist drug
5. A drug that reduces or blocks the effect of another drug
Correct Answer: Antagonist drug
6. The study of the effects of drugs and their mechanisms of action
Correct Answer: Pharmacodynamics
7. The study of the drug cycle: absorption, distribution, metabolism, and
excretion
Correct Answer: Pharmacokinetics
8. The study of genetic variation and its influence on drug response
Correct Answer: Pharmacogenetics
,9. How are synthetic drugs produced?
Correct Answer: Through chemical processes, genetic engineering, or
alteration of animal cells
10. Drugs that restore normal physiological function
Correct Answer: Curative drugs
11. Drugs used to prevent disease or disorders
Correct Answer: Prophylactic drugs
12. Drugs used to diagnose disease
Correct Answer: Diagnostic drugs
13. Drugs used to relieve pain or symptoms
Correct Answer: Palliative drugs
14. Drugs that replace missing substances in the body
Correct Answer: Replacement drugs
15. Drugs that destroy tumors or microbes
Correct Answer: Destructive drugs
16. Major sources of drugs
Correct Answer: Plant, animal, mineral, toxins, synthetic
17. Why are drugs grouped into classes?
Correct Answer: They share chemical characteristics, mechanisms of action,
or therapeutic purposes
18. Phase I clinical trials determine what?
Correct Answer: Drug safety
19. Phase II clinical trials involve what?
Correct Answer: Hundreds of patients over longer periods
20. Phase III clinical trials are conducted to evaluate what?
Correct Answer: Safety, effectiveness, and dosage at multiple facilities
,21. What is a drug called during the first three phases of trials?
Correct Answer: Investigational New Drug (IND)
22. What is compassionate use of an IND?
Correct Answer: FDA allows use for critically ill patients
23. What is a New Drug Application (NDA)?
Correct Answer: Application submitted to the FDA for drug approval
24. What occurs during Phase IV trials?
Correct Answer: Ongoing evaluation for risks and benefits (e.g., MedWatch)
25. What is a brand or trade name?
Correct Answer: The name given after successful Phase I–III trials
26. When was the DEA established?
Correct Answer: 1973
27. What is the purpose of the DEA?
Correct Answer: Enforce controlled substance laws and regulate manufacture,
distribution, and dispensing
28. Schedule I drugs are characterized by what?
Correct Answer: High abuse potential, no medical use, illegal
29. Schedule II drugs are characterized by what?
Correct Answer: High addiction potential, no refills, written prescription only
30. Schedule III drugs are characterized by what?
Correct Answer: Moderate dependence risk, refills allowed (up to five in six
months)
31. Schedule IV drugs are characterized by what?
Correct Answer: Lower abuse potential
32. Schedule V drugs are characterized by what?
Correct Answer: Lowest abuse potential
, 33. Examples of Schedule I drugs
Correct Answer: Heroin, marijuana, LSD, methamphetamine
34. Examples of Schedule II drugs
Correct Answer: Cocaine, hydrocodone, methamphetamine, morphine,
oxycodone, Ritalin
35. Examples of Schedule III drugs
Correct Answer: Anabolic steroids, Tylenol-3, ketamine, testosterone
36. Examples of Schedule IV drugs
Correct Answer: Ambien, Ativan, tramadol, Valium, Xanax
37. Examples of Schedule V drugs
Correct Answer: Codeine cough syrup, Lomotil
38. Effects of anabolic steroid use
Correct Answer: Hormonal disruption, musculoskeletal effects, infections,
cardiovascular disease, liver dysfunction, behavioral changes
39. Psychological dependence on a drug
Correct Answer: Habituation
40. Common withdrawal symptoms
Correct Answer: Tremors, emotional distress, hallucinations
41. Common physical signs of substance abuse
Correct Answer: Sleep changes, weight change, sweating, confusion, slow
reflexes, jaundice, pupil changes, needle marks, hygiene changes
42. The drug cycle consists of what?
Correct Answer: Absorption, distribution, metabolism (biotransformation),
excretion
43. Factors influencing completion of the drug cycle
Correct Answer: Drug properties, route of administration, organ health