WGU D398 Pharmacology
Objective Assessment Comprehensive Resource To Help
You Ace 2026-2027 Includes Frequently Tested Questions
With ELABORATED 100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. What is the classification, mechanism of action, and major adverse effects of
Clozapine, Olanzapine (Zyprexa), and Quetiapine (Seroquel)?
Correct Answer:
• Classification: Atypical antipsychotics
• Mechanism: Block dopamine and serotonin receptors
• Indication: Schizophrenia
• Adverse Effects: Weight gain, dry mouth, endocrine effects
2. What is the mechanism of action, indication, and key nursing considerations
for Fluoxetine (Prozac)?
Correct Answer:
• Class: SSRI
• Mechanism: Blocks serotonin reuptake → increases monoamines
• Indication: Depression
• Teaching: Administer with food
• Adverse Effects: Sexual dysfunction, serotonin syndrome (altered LOC,
tremor, hyperreflexia)
,3. What is the mechanism and major adverse effects of Venlafaxine (Effexor)?
Correct Answer:
• Class: SNRI
• Mechanism: Blocks norepinephrine and dopamine reuptake
• Adverse Effects: Nervousness, hypertension
4. What are the major adverse effects and contraindications of Tricyclic
Antidepressants (Amitriptyline, Doxepin)?
Correct Answer:
• Adverse Effects: Hypotension, cardiotoxicity
• Overdose Treatment: Gastric lavage and sodium bicarbonate
• Avoid: MAOIs and anticholinergics
5. What are the key safety considerations for MAOIs (Isocarboxazid, Phenelzine,
Tranylcypromine)?
Correct Answer:
• Mechanism: Inhibit monoamine oxidase → prevent neurotransmitter
breakdown
• Adverse Effects: Hypertension/hypotension, agitation
• Important Teaching: Avoid tyramine-containing foods
6. What are the major adverse effects of Bupropion (Wellbutrin)?
Correct Answer:
, • Mechanism: Blocks dopamine and norepinephrine reuptake
• Adverse Effects: Seizures, agitation
7. What is a common adverse effect of Mirtazapine (Remeron)?
Correct Answer:
• Sexual dysfunction
• Weight gain
8. What are the effects and toxicity signs of Bethanechol?
Correct Answer:
• Class: Muscarinic agonist
• Indication: Urinary retention
• Adverse Effects: DUMBELS (Diaphoresis, Urination, Miosis, Bronchospasm,
Emesis, Lacrimation, Salivation)
• Antidote: Atropine
9. What is the mechanism and risk of Pyridostigmine and Donepezil?
Correct Answer:
• Class: Cholinesterase inhibitors
• Mechanism: Prevent breakdown of acetylcholine
• Adverse Effects: Paralysis, GI/urinary obstruction
10. What are the effects of Alpha-1 receptor stimulation?
Correct Answer:
• Vasoconstriction
, • Pupil dilation
• Increased BP (baroreceptor reflex → ↓ HR)
11. What are the effects of Beta-1 receptor stimulation?
Correct Answer:
• Increased heart rate
• Increased cardiac output
• Adverse: Tachycardia, arrhythmias
12. What are the effects of Beta-2 receptor stimulation?
Correct Answer:
• Bronchodilation
• Smooth muscle relaxation
• Adverse: Tremor, hyperglycemia
13. What are the indications and adverse effects of Epinephrine?
Correct Answer:
• Receptors: α1, α2, β1, β2
• Uses: Cardiac arrest, anaphylaxis
• Adverse Effects: Hypertension, angina, hyperglycemia
• Avoid with: MAOIs and TCAs
14. What is Dopamine used for and what should be monitored?
Correct Answer:
• Uses: Shock, ↑ cardiac output, ↑ perfusion
• Monitor: Urine output, signs of heart failure
Objective Assessment Comprehensive Resource To Help
You Ace 2026-2027 Includes Frequently Tested Questions
With ELABORATED 100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. What is the classification, mechanism of action, and major adverse effects of
Clozapine, Olanzapine (Zyprexa), and Quetiapine (Seroquel)?
Correct Answer:
• Classification: Atypical antipsychotics
• Mechanism: Block dopamine and serotonin receptors
• Indication: Schizophrenia
• Adverse Effects: Weight gain, dry mouth, endocrine effects
2. What is the mechanism of action, indication, and key nursing considerations
for Fluoxetine (Prozac)?
Correct Answer:
• Class: SSRI
• Mechanism: Blocks serotonin reuptake → increases monoamines
• Indication: Depression
• Teaching: Administer with food
• Adverse Effects: Sexual dysfunction, serotonin syndrome (altered LOC,
tremor, hyperreflexia)
,3. What is the mechanism and major adverse effects of Venlafaxine (Effexor)?
Correct Answer:
• Class: SNRI
• Mechanism: Blocks norepinephrine and dopamine reuptake
• Adverse Effects: Nervousness, hypertension
4. What are the major adverse effects and contraindications of Tricyclic
Antidepressants (Amitriptyline, Doxepin)?
Correct Answer:
• Adverse Effects: Hypotension, cardiotoxicity
• Overdose Treatment: Gastric lavage and sodium bicarbonate
• Avoid: MAOIs and anticholinergics
5. What are the key safety considerations for MAOIs (Isocarboxazid, Phenelzine,
Tranylcypromine)?
Correct Answer:
• Mechanism: Inhibit monoamine oxidase → prevent neurotransmitter
breakdown
• Adverse Effects: Hypertension/hypotension, agitation
• Important Teaching: Avoid tyramine-containing foods
6. What are the major adverse effects of Bupropion (Wellbutrin)?
Correct Answer:
, • Mechanism: Blocks dopamine and norepinephrine reuptake
• Adverse Effects: Seizures, agitation
7. What is a common adverse effect of Mirtazapine (Remeron)?
Correct Answer:
• Sexual dysfunction
• Weight gain
8. What are the effects and toxicity signs of Bethanechol?
Correct Answer:
• Class: Muscarinic agonist
• Indication: Urinary retention
• Adverse Effects: DUMBELS (Diaphoresis, Urination, Miosis, Bronchospasm,
Emesis, Lacrimation, Salivation)
• Antidote: Atropine
9. What is the mechanism and risk of Pyridostigmine and Donepezil?
Correct Answer:
• Class: Cholinesterase inhibitors
• Mechanism: Prevent breakdown of acetylcholine
• Adverse Effects: Paralysis, GI/urinary obstruction
10. What are the effects of Alpha-1 receptor stimulation?
Correct Answer:
• Vasoconstriction
, • Pupil dilation
• Increased BP (baroreceptor reflex → ↓ HR)
11. What are the effects of Beta-1 receptor stimulation?
Correct Answer:
• Increased heart rate
• Increased cardiac output
• Adverse: Tachycardia, arrhythmias
12. What are the effects of Beta-2 receptor stimulation?
Correct Answer:
• Bronchodilation
• Smooth muscle relaxation
• Adverse: Tremor, hyperglycemia
13. What are the indications and adverse effects of Epinephrine?
Correct Answer:
• Receptors: α1, α2, β1, β2
• Uses: Cardiac arrest, anaphylaxis
• Adverse Effects: Hypertension, angina, hyperglycemia
• Avoid with: MAOIs and TCAs
14. What is Dopamine used for and what should be monitored?
Correct Answer:
• Uses: Shock, ↑ cardiac output, ↑ perfusion
• Monitor: Urine output, signs of heart failure
