week 1 Walden 6501 advanced
pathophysiology
Acrocentric - ANS-refers back to the terminal area of centromere on chromosomes 13, 14, 15,
21, and 22
allelic heterogeneity - ANS-the scenario in which more than one alleles at a single locus can
produce one or extra ailment phenotypes.
Amorphic - ANS-refers ro mutations that reason a entire lack of feature for the respective gene,
and therefore yield the equal phenotype as a whole gene deletion.
Aneuploidy - ANS-a wellknown term used to denote any unbalanced chromosome complement
antimorphic - ANS-refers to mutations that once found in heterozygous form opposite a
nonmutant allele will result in a phenotype much like homozygous for lack of function alleles.
Ascertainment bias - ANS-the situation in which individuals or households in a genetic examine
are not consultant of the overall populace due to the manner in which they may be identified
autosomal - ANS-placed on chromosomes 1-22 rather than x or y
CpG island - ANS-a phase of DNA that consists of a rather excessive density of 5' - CG-3'
dinucleotides. Such segments are frequently unmethylated and placed near ubiquitously
expressed genes.
Dictyotene - ANS-the cease of prophase for the duration of girl meiosis I in which fetal oocytes
are arrested previous to ovulation.
Dominant - ANS-a sample of inheritance or mechanism of gene movement wherein the
outcomes of a version allele can be found in the presence of a nonmutant allele.
Dominant bad - ANS-a type of pathophysiologic mechanism that takes place whilst a mutant
allele interferes with the ordinary characteristic of the nonmutant gene product.
Dosage repayment - ANS-mechanismby which a distinction in gene dosage between cells is
equalized. For XX cells in mammals, decreased expression from one of the X chromosomes
consequences in a attention of gene product much like am XY mobile.
pathophysiology
Acrocentric - ANS-refers back to the terminal area of centromere on chromosomes 13, 14, 15,
21, and 22
allelic heterogeneity - ANS-the scenario in which more than one alleles at a single locus can
produce one or extra ailment phenotypes.
Amorphic - ANS-refers ro mutations that reason a entire lack of feature for the respective gene,
and therefore yield the equal phenotype as a whole gene deletion.
Aneuploidy - ANS-a wellknown term used to denote any unbalanced chromosome complement
antimorphic - ANS-refers to mutations that once found in heterozygous form opposite a
nonmutant allele will result in a phenotype much like homozygous for lack of function alleles.
Ascertainment bias - ANS-the situation in which individuals or households in a genetic examine
are not consultant of the overall populace due to the manner in which they may be identified
autosomal - ANS-placed on chromosomes 1-22 rather than x or y
CpG island - ANS-a phase of DNA that consists of a rather excessive density of 5' - CG-3'
dinucleotides. Such segments are frequently unmethylated and placed near ubiquitously
expressed genes.
Dictyotene - ANS-the cease of prophase for the duration of girl meiosis I in which fetal oocytes
are arrested previous to ovulation.
Dominant - ANS-a sample of inheritance or mechanism of gene movement wherein the
outcomes of a version allele can be found in the presence of a nonmutant allele.
Dominant bad - ANS-a type of pathophysiologic mechanism that takes place whilst a mutant
allele interferes with the ordinary characteristic of the nonmutant gene product.
Dosage repayment - ANS-mechanismby which a distinction in gene dosage between cells is
equalized. For XX cells in mammals, decreased expression from one of the X chromosomes
consequences in a attention of gene product much like am XY mobile.
