Pathophysiology Final Exam
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Acute renal failure - 🧠 ANSWER ✔✔Reversible
Determining prognosis- kidneys respond to diuretic with good output; this
indicates that kidneys are functioning well
Acute Pyelonephritis - 🧠 ANSWER ✔✔Diagnosing by clinical symptoms
alone can be difficult; can be similar to cystitis
,Diagnosis established by:
-Urine culture
-Urinalysis (WBC casts indicates pyelonephritis, but may not always be
present)
-Signs/Symptoms
-Complicated pyelonephritis requires blood cultures and urinary tract
imaging
Renal Calculi (Renal Stones) - 🧠 ANSWER ✔✔Goals of Treatment:
Manage acute pain
Promote passage of stone
Reduce size of stone
Prevent new stone formation
Chronic Renal Failure - 🧠 ANSWER ✔✔Chronic Kidney Disease (CKD) is a
progressive loss of renal function associated with systemic disease such as
hypertension, diabetes mellitus (most significant risk factor), systemic lupus
erythematosus or intrinsic kidney disease
, CKD stage is determined by estimates of GFR and albuminuria
Who is a candidate for dialysis? - 🧠 ANSWER ✔✔End-stage renal disease
(ESRD) is the final stage of CKD with the number one cause being
diabetes mellitus combined with hypertension. At this point, the patient is
completely dependent on dialysis to survive.
CKD is classified into five stages and is based on the patient's GFR rather
than symptoms.
Patients will need dialysis when the following symptoms are present:
--Metabolic acidosis.
--Hyperkalemia: Hyperkalemia in the presence of EKG changes (peaked T-
waves) is an indication for dialysis. --Hyperkalemia by itself is not an
indication for dialysis.
--Drug toxicity: Drug toxicity due to the following drugs is an indication for
dialysis and include salicylates, Lithium, Isopropanol, Methanol and
Ethylene glycol).
--Fluid volume overload that is not responsive to diuretics.
--Uremic symptoms due to nitrogenous wastes in the blood stream.
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