https://www.stuvia.com/
,TESTBANKFORMODERN BLOOD BANKING & ss s ss
TRANSFUSION PRACTICES 7TH EDITION BY
ss ss ss ss ss
DENISE M HARMENING
ss ss ss
9780803668881CHAPTER1-29COMPLETE
s s
GUIDE ss
,https://www.stuvia.com/
Chapter 1 RBCsand Platelet Preservation: Historical Perspectives and Current Trends
ss ss ss ss ss xx ss ss ss
Multiple ssChoice
Identify ssthe sschoice ssthat ssbest sscompletes ssthe ssstatement ssor ssanswers ssthe ssquestion.
1. Which metabolic sspathwayssis ssresponsible ssfor ssgenerating ss90% ssof ssthessATPssfor ssthe ssRBC?
xx
a. Pentose ssphosphate ssshunt c. Glycolysis
b. Luebering-Rapoport s s shunt d. Methemoglobin ssreductase
2. A ssunit ssof ssblood sswas ssreturned ssto ssthe ssblood ssbank ssbefore ssit sswas ssspiked. ssApparently ssthe sspatient’s ssIV
ssfailed. ssThe ssunit ssof ssblood sswas ssoutside ssthe ssblood ssbank ssfor ss35 ssminutes. ssWhich ssof ssthe ssstatements
ssbelow ssis ssmost ssaccurate?
a. The ssunit ssof ssblood ssshould ssbe ssdiscarded ssimmediately.
b. The ssunit ssof ssblood sscan ssbe ssreturned ssto ssinventory.
c. The ssunit ssof ssblood ss must s s be sstransfused sswithin ss4 sshours ssor ssbe s s discarded ssat ssthe ssend ssof ssthat s s time.
d. The ssunit ssof s s blood ssmust s s be sstransfused sswith ss24 sshours.
3. What ssis ssthe ssaverage ss diameter s s of s s a s s platelet?
a. 5 s s to s s 10 s s µm c. 1 s s to s s 2 s s µm
b. 2 s s to s s 4 s s µm d. 4 s s to s s 6 s s µm
4. In ssthe ssnormal sshemoglobin-oxygen ssdissociation sscurve, sswhat sspercentage ssof ssoxygen ssis released xx
ssto ssthe sstissues sswhen ssPO2 s s averages ss40 ssmm ssHg?
a. 75% c. 100%
b. 25% d. 50%
5. What ssfactors ssare ssknown ssto ssinfluence ssplatelet ssmetabolism and ssfunction? xx
a. Storage sstemperature c. Platelet sscount
b. Initial sspH d. All ss of ssthe s s above
6. Which ssof ssthe ssfollowing ssred ssblood sscell ssmorphologies ssmay ssbe sspresent sson ssthe ssperipheral ssblood
sssmear ssas ssa ssresult ssof ssloss ssof ssRBC ssmembrane?
a. Spherocytes c. Burr cells xx
b. Target sscells d. Schistocytes
7. What ssdoes ssthe ssterm ssautologous transfusion ssrefer ss to?
xx
a. Assparent s s donating ssblood for sshis s s or s s her child
xx xx
b. An ssindividual ssdonating ssblood ssfor ssa friend xx
c. An ssindividual donating ssblood for ssa ssrelative
xx xx
d. An ssindividual donating ssblood ssfor his ssor ssher ssown sstransfusion
xx xx
8. What is ssthe ssprimary ssfunction of sshemoglobin?
xx xx
a. Iron ssmetabolism c. Oxygen sstransport
b. Porphyrin sssynthesis d. Signal s s transduction
9. All ssof ssthe ssfollowing ssareas ssof ssred ssblood sscell ssbiology ssare sscrucial ssfor ssnormal s s erythrocyte sssurvival ss except:
a. Cellular ssmetabolism. c. Site ssof ssthessABO ssantigen ssattachment.
b. RBC ssmembrane. d. Hemoglobin ssstructure.
This ssstudy sssource ss was ss downloaded s s by ss 100000826342158 ss from ss CourseHero.com ss on ss 09-15-2021
17:54:15 GMT -
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
ss 10. What ssis ssthe s s correct s s biochemical s s composition ssof s s the s s RBC ss membrane?
a. 52% ssprotein, ss40% sslipid, ss8% sscarbohydrate
b. 40% ssprotein, ss8% sslipid, ss52% sscarbohydrate
c. 8% ssprotein, ss52% sslipid, ss40% sscarbohydrate
d. 8% sslipid, ss40% sscarbohydrate, ss52% ssprotein
ss 11. All ssof ssthe ssfollowing ssbiochemical s s changes s s are ss associated sswith ssloss ssof ssred ssblood sscell s s viability ssupon
storage
ss
except:
a. Decreased sspH. c. Increased ATP sslevel.
xx
b. Loss ssof ssred ssblood sscell s s function. d. Decreased ssglucose ssconsumption.
ss 12. Which ssred ss blood s s cell sspreservative s s has s s a s s storage ss time s s of s s 35 s s days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
ss 13. The s s RBC s s membrane s s is s s relatively sspermeable s s to s s all s s of ssthe ssfollowing s s except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water.
ss 14. ssWhat sspercentage ssof ssplatelets ssis sssequestered ssin ssthe ssspleen ssas ssfunctional ssreserve ssafter ssbeing
ssreleased ssfrom ssthe ssbone ssmarrow?
a. 30% c. 10%
b. 50% d. 25%
ss 15. What ssis ssthe s s major s s biochemical s s consideration ssin platelet s s storage?
xx
a. Glucose ssmetabolism c. Production ssof sscarbon ssdioxide
b. Oxygen sssupply d. s s s s s s Regulation s s of s s pH
x x
ss 16. ssWhat sswould ssthe sshemoglobin-oxygen ssdissociation sscurve ssdepict ssin a sspatient ssexhibiting ssclinical
xx
sssigns ssof ssalkalosis?
a. Normal c. Shift ssto the ss right xx
b. Shift ssto ssthe s s left d. None s s of s s the s s above
ss 17. Name s s the s s main s s lipid sscomponents s s of s s a ssred blood sscell s s membrane.
xx
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin ssA
ss 18. The ssABO ss blood s s groups s s were s s discovered s s in s s 1901 ss by sswhom?
a. Charles Drew xx c. Loutit ssand ssMollison
b. Karl Landsteiner
xx d. Edward ssLindeman
s s 19. s s A s s standing s s order s s of s s platelets was s s shipped s s to s s your s s facility s s by s s your s s supplier. s s It s s was
xx
s s inadvertently s s left s s in ssthe sscorner ssof ssthe ssdepartment ssuntil ssdiscovered ss36 sshours sslater. ssWhat sswould
ssthe ssappropriate ssaction ssbe ssfor ssthe ssblood ssbanker?
a. If ssthe sstemperature ssin ssthe ssbox sswas ss22 ss+/- ss2°C ssand ssthe ssplatelet ssswirl ssseemed ssOK, ssit
sswould ssbe ssOK ssto ssaccept ssthe ssunit ssinto ssinventory.
b. The ssplatelets sshave ssfallen ssoutside ssthe sssupplier’s ssquality ssassurance. ssThe ssunit
ssshould ssbe s s discarded ssbecause ssthe sspH sshas ssprobably ssdropped sstoo sslow ssand
ssplatelet ssactivation sshas ssbeen sscompromised.
c. If ssthe sstemperature sswas s s 1°C ssto ss6°C ssand ssthe ssplatelet ssswirl s s seemed s s OK, ssit sswould ssbe ssOK ssto
This ssstudy sssource ss was ss downloaded s s by ss 100000826342158 ss from ss CourseHero.com ss on ss 09-15-2021
17:54:15 GMT -
https://www.coursehero.com/file/25537437/ch01rtf/
,TESTBANKFORMODERN BLOOD BANKING & ss s ss
TRANSFUSION PRACTICES 7TH EDITION BY
ss ss ss ss ss
DENISE M HARMENING
ss ss ss
9780803668881CHAPTER1-29COMPLETE
s s
GUIDE ss
,https://www.stuvia.com/
Chapter 1 RBCsand Platelet Preservation: Historical Perspectives and Current Trends
ss ss ss ss ss xx ss ss ss
Multiple ssChoice
Identify ssthe sschoice ssthat ssbest sscompletes ssthe ssstatement ssor ssanswers ssthe ssquestion.
1. Which metabolic sspathwayssis ssresponsible ssfor ssgenerating ss90% ssof ssthessATPssfor ssthe ssRBC?
xx
a. Pentose ssphosphate ssshunt c. Glycolysis
b. Luebering-Rapoport s s shunt d. Methemoglobin ssreductase
2. A ssunit ssof ssblood sswas ssreturned ssto ssthe ssblood ssbank ssbefore ssit sswas ssspiked. ssApparently ssthe sspatient’s ssIV
ssfailed. ssThe ssunit ssof ssblood sswas ssoutside ssthe ssblood ssbank ssfor ss35 ssminutes. ssWhich ssof ssthe ssstatements
ssbelow ssis ssmost ssaccurate?
a. The ssunit ssof ssblood ssshould ssbe ssdiscarded ssimmediately.
b. The ssunit ssof ssblood sscan ssbe ssreturned ssto ssinventory.
c. The ssunit ssof ssblood ss must s s be sstransfused sswithin ss4 sshours ssor ssbe s s discarded ssat ssthe ssend ssof ssthat s s time.
d. The ssunit ssof s s blood ssmust s s be sstransfused sswith ss24 sshours.
3. What ssis ssthe ssaverage ss diameter s s of s s a s s platelet?
a. 5 s s to s s 10 s s µm c. 1 s s to s s 2 s s µm
b. 2 s s to s s 4 s s µm d. 4 s s to s s 6 s s µm
4. In ssthe ssnormal sshemoglobin-oxygen ssdissociation sscurve, sswhat sspercentage ssof ssoxygen ssis released xx
ssto ssthe sstissues sswhen ssPO2 s s averages ss40 ssmm ssHg?
a. 75% c. 100%
b. 25% d. 50%
5. What ssfactors ssare ssknown ssto ssinfluence ssplatelet ssmetabolism and ssfunction? xx
a. Storage sstemperature c. Platelet sscount
b. Initial sspH d. All ss of ssthe s s above
6. Which ssof ssthe ssfollowing ssred ssblood sscell ssmorphologies ssmay ssbe sspresent sson ssthe ssperipheral ssblood
sssmear ssas ssa ssresult ssof ssloss ssof ssRBC ssmembrane?
a. Spherocytes c. Burr cells xx
b. Target sscells d. Schistocytes
7. What ssdoes ssthe ssterm ssautologous transfusion ssrefer ss to?
xx
a. Assparent s s donating ssblood for sshis s s or s s her child
xx xx
b. An ssindividual ssdonating ssblood ssfor ssa friend xx
c. An ssindividual donating ssblood for ssa ssrelative
xx xx
d. An ssindividual donating ssblood ssfor his ssor ssher ssown sstransfusion
xx xx
8. What is ssthe ssprimary ssfunction of sshemoglobin?
xx xx
a. Iron ssmetabolism c. Oxygen sstransport
b. Porphyrin sssynthesis d. Signal s s transduction
9. All ssof ssthe ssfollowing ssareas ssof ssred ssblood sscell ssbiology ssare sscrucial ssfor ssnormal s s erythrocyte sssurvival ss except:
a. Cellular ssmetabolism. c. Site ssof ssthessABO ssantigen ssattachment.
b. RBC ssmembrane. d. Hemoglobin ssstructure.
This ssstudy sssource ss was ss downloaded s s by ss 100000826342158 ss from ss CourseHero.com ss on ss 09-15-2021
17:54:15 GMT -
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
ss 10. What ssis ssthe s s correct s s biochemical s s composition ssof s s the s s RBC ss membrane?
a. 52% ssprotein, ss40% sslipid, ss8% sscarbohydrate
b. 40% ssprotein, ss8% sslipid, ss52% sscarbohydrate
c. 8% ssprotein, ss52% sslipid, ss40% sscarbohydrate
d. 8% sslipid, ss40% sscarbohydrate, ss52% ssprotein
ss 11. All ssof ssthe ssfollowing ssbiochemical s s changes s s are ss associated sswith ssloss ssof ssred ssblood sscell s s viability ssupon
storage
ss
except:
a. Decreased sspH. c. Increased ATP sslevel.
xx
b. Loss ssof ssred ssblood sscell s s function. d. Decreased ssglucose ssconsumption.
ss 12. Which ssred ss blood s s cell sspreservative s s has s s a s s storage ss time s s of s s 35 s s days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
ss 13. The s s RBC s s membrane s s is s s relatively sspermeable s s to s s all s s of ssthe ssfollowing s s except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water.
ss 14. ssWhat sspercentage ssof ssplatelets ssis sssequestered ssin ssthe ssspleen ssas ssfunctional ssreserve ssafter ssbeing
ssreleased ssfrom ssthe ssbone ssmarrow?
a. 30% c. 10%
b. 50% d. 25%
ss 15. What ssis ssthe s s major s s biochemical s s consideration ssin platelet s s storage?
xx
a. Glucose ssmetabolism c. Production ssof sscarbon ssdioxide
b. Oxygen sssupply d. s s s s s s Regulation s s of s s pH
x x
ss 16. ssWhat sswould ssthe sshemoglobin-oxygen ssdissociation sscurve ssdepict ssin a sspatient ssexhibiting ssclinical
xx
sssigns ssof ssalkalosis?
a. Normal c. Shift ssto the ss right xx
b. Shift ssto ssthe s s left d. None s s of s s the s s above
ss 17. Name s s the s s main s s lipid sscomponents s s of s s a ssred blood sscell s s membrane.
xx
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin ssA
ss 18. The ssABO ss blood s s groups s s were s s discovered s s in s s 1901 ss by sswhom?
a. Charles Drew xx c. Loutit ssand ssMollison
b. Karl Landsteiner
xx d. Edward ssLindeman
s s 19. s s A s s standing s s order s s of s s platelets was s s shipped s s to s s your s s facility s s by s s your s s supplier. s s It s s was
xx
s s inadvertently s s left s s in ssthe sscorner ssof ssthe ssdepartment ssuntil ssdiscovered ss36 sshours sslater. ssWhat sswould
ssthe ssappropriate ssaction ssbe ssfor ssthe ssblood ssbanker?
a. If ssthe sstemperature ssin ssthe ssbox sswas ss22 ss+/- ss2°C ssand ssthe ssplatelet ssswirl ssseemed ssOK, ssit
sswould ssbe ssOK ssto ssaccept ssthe ssunit ssinto ssinventory.
b. The ssplatelets sshave ssfallen ssoutside ssthe sssupplier’s ssquality ssassurance. ssThe ssunit
ssshould ssbe s s discarded ssbecause ssthe sspH sshas ssprobably ssdropped sstoo sslow ssand
ssplatelet ssactivation sshas ssbeen sscompromised.
c. If ssthe sstemperature sswas s s 1°C ssto ss6°C ssand ssthe ssplatelet ssswirl s s seemed s s OK, ssit sswould ssbe ssOK ssto
This ssstudy sssource ss was ss downloaded s s by ss 100000826342158 ss from ss CourseHero.com ss on ss 09-15-2021
17:54:15 GMT -
https://www.coursehero.com/file/25537437/ch01rtf/
