ANSWERS | LATEST ALREADY GRADED A+
Clinical manifestations for RA - CORRECT ANSWERS--Rubor(redness), Dolor(pain),
Tumor(swelling), Calor(heat), Functio laesa(impaired function)
-Joint malformation
-Pain and stiffness especially in AM and after immobility
Systemic sx
-Fever, fatigue, anorexia, weight loss, weakness
-Isolation and depression
-Granulomas, vasculitis
Clinical manifestations for dx (RA) - CORRECT ANSWERS--Morning stiffness for at least one
hour and present for at least six weeks
-Swelling of three or more joints for at least six weeks
-Swelling of wrist, metacarpophalangeal, or proximal interphalangeal joints for at least six weeks
-Symmetric joint swelling
-Hand x-ray changes typical of RA that include erosions or bony decalcification
-Rheumatoid subcutaneous nodules
-Rheumatoid factors or anti-citrullinated peptide/protein antibodies
-Elevated acute phase reactants (erythrocyte sedimentation rate or
C-reactive protein)
Patterns of progression of RA - CORRECT ANSWERS--Most patients show fluctuation of
disease activity over periods lasting weeks to months. (This corresponds to an increase or decrease in
symptoms of arthritis, a pattern which may recur throughout the course of the disease.)
-Disease activity may not abate in about 10 to 20 percent of cases.
-Remission has been reported in a small proportion of patients with a well established diagnosis of RA.
(This is very rare without disease modifying antirheumatic drugs (DMARDs). As an example, among 191
patients treated with such drugs beginning within a year of disease onset, 48 (25 percent) met criteria