Sciences Mastery 2026: Personality
Disorders, Schizophrenia Spectrum, Mood &
Anxiety Disorders, Trauma, PTSD, Somatic &
Dissociative Disorders, Eating Disorders,
ADHD, Sleep & Sexual Dysfunctions,
Psychopharmacology, Psychotherapy, CBT,
DBT, OMM & Exam-Ready Clinical Insights
Questions Verified and Complete with A+
Graded Rationales Latest Updated
Pscyhosis
a loss of contact with reality that usally includes delusions and hallucinations
EtOH and BZD Withdrawal
Withdrawal that is highly assoc with psychosis (delusions and hallucinations)
Positive
Ex of ______________ Symptoms:
-delusions
-hallucinations
-disorganized speech and behavior
Negative
Ex of __________________ Symptoms:
-social withdrawal
-flat affect
-apathy
-anhedonia
-avolition
-alogia
Schizophrenia
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,Dx that requires at least 2 symptoms and impaired social/occupation/interpersonal function
for > 6 months:
-delusions, hallucinations, disorganized speech and behavior
-social withdrawal, flat affect, apathy, anhedonia, avolition, alogia
-poor memory, attention deficits, inability to organize or form abstractions
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A diagnosis of Schizophrenia needs at least ______ symptoms for greater than ____ months
Paranoid
most common form of schizophrenia and has the best prognosis
Catatonic
______________ Schizophrenia:
-rigid posutring
-poor response to stimuli
-poor interaction
Disorganized
______________ Schizophrenia:
-falt/inappropriate affect
-disorganized speech
-inappropriate and disorganized behavior
-neglect themselves
Undifferential
______________ Schizophrenia:
-does not fit into any other subtype
Residual
______________ Schizophrenia:
-when there is resolution of positive sx but lingering negative sx
Schizophrenia
assoc with a second hit that causes the disease
Increased
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, in Schizophrenia, Dopamine is _____________
Schizophrenia
-dopmain is increased
-transmethylation-breakdown of depamine, NE, and serotonin which produces hallucinogenic
materials
-hypofunction in NMDA receptors within glutamate system
-increased CSF, decreased cortical gray matter, enlarged ventricles and sulci
Typical Antipsychotics
-ex: haloperidol, fluphenazine, etc.
-blocks D2 receptors
-indicated for emergency control of psychosis, for positive symptoms
-2nd line for maintenance
-AEs: extrapyramidal sx
Atypical Antipsychotics
-ex: clozapine, quetiapine, risperadone
-blocks dopamine AND serotonin receptors
-first line for maintenance therapy
-better for negative sx
Clozapine
-atypical antipsychotic assoc with agranulocytosis
-also the most effective agent
Delusional
presence of 1+ delusion for > 1month without any psychosis or other +/- symptoms, patient can
function normally
Schizophreniform
symptoms lasting > 1 month but < 6 months. 75% of patients go on to develop schizophrenia
Brief Psychotic Episode
a. sudden sx last at least 1 day but < 1 month & occur in response to a stressful life event
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