NSG 6005 Pharm Weeks 1-3 Quiz (from operationFNP Class
11) Questions With Complete Solutions
A genetic variation in how the metabolite of the cancer drug
irinotecan SN-38 is inactivated by the body may lead to:
1. Decreased effectiveness of irinotecan in the treatment of
cancer
2. Increased adverse drug reactions, such as neutropenia
3. Delayed metabolism of the prodrug irinotecan into the active
metabolite SN-38
4. Increased concerns for irinotecan being carcinogenic Correct
Answers 2. Increased adverse drug reactions, such as
neutropenia
A good history of herb and supplement use is critical before
prescribing because approximately ____ % of patients in the
United States are using herbal products.
1. 10
2. 5
3. 38
4. 70 Correct Answers 3. 38
A low-carbohydrate, high-protein diet may:
,1. Increase drug-metabolizing enzymes
2. Decrease drug absorption from the GI tract
3. Alter drug binding to plasma proteins
4. Enhance drug elimination Correct Answers 1. Increase drug-
metabolizing enzymes
A medication review of an elderly person's medications
involves:
1. Asking the patient to bring a list of current prescription
medications to the visit
2. Having the patient bring all of their prescription, over-the-
counter, and herbal medications to the visit
3. Asking what other providers are writing prescriptions for
them
4. All of the above Correct Answers 4. All of the above
A number of barriers and concerns exist before the goals of a
safe and efficient information technology (IT) system can be
realized. Which of the following is NOT a barrier to adoption
and use of IT in prescribing drugs?
1. Cost of initial setup
,2. Access to highly skilled experts
3. Compatibility between systems
4. Patient confidentiality risks Correct Answers 2. Access to
highly skilled experts
A patient with a new onset of systolic ejection murmur should
be assessed for which nutritional deficiency?
1. Vitamin B12
2. Vitamin C
3. Folate
4. Niacine Correct Answers 3. Folate
A potential harmful effect on patients who take some herbal
medication is:
1. Constipation
2. Lead poisoning
3. Diarrhea
4. Life-threatening rash Correct Answers 2. Lead poisoning
A provider may consider testing for CYP2D6 variants prior to
starting tamoxifen for breast cancer to:
, 1. Ensure the patient will not have increased adverse drug
reactions to the tamoxifen
2. Identify potential drug-drug interactions that may occur with
tamoxifen
3. Reduce the likelihood of therapeutic failure with tamoxifen
treatment
4. Identify poor metabolizers of tamoxifen Correct Answers 3.
Reduce the likelihood of therapeutic failure with tamoxifen
treatment
A thorough understanding of herbs is critical to patient safety.
An example is the use of cinnamon to treat type II diabetes. It is
important the patient uses Ceylon cinnamon, as the
commercially available cassia cinnamon contains:
1. Coumadin, which may lead to bleeding problems
2. Coumarin, which can cause liver and kidney damage
3. Cinnamic aldehyde, which is toxic to the kidney
4. Cinnamate eugenol, which is toxic to the liver Correct
Answers 2. Coumarin, which can cause liver and kidney
damage
11) Questions With Complete Solutions
A genetic variation in how the metabolite of the cancer drug
irinotecan SN-38 is inactivated by the body may lead to:
1. Decreased effectiveness of irinotecan in the treatment of
cancer
2. Increased adverse drug reactions, such as neutropenia
3. Delayed metabolism of the prodrug irinotecan into the active
metabolite SN-38
4. Increased concerns for irinotecan being carcinogenic Correct
Answers 2. Increased adverse drug reactions, such as
neutropenia
A good history of herb and supplement use is critical before
prescribing because approximately ____ % of patients in the
United States are using herbal products.
1. 10
2. 5
3. 38
4. 70 Correct Answers 3. 38
A low-carbohydrate, high-protein diet may:
,1. Increase drug-metabolizing enzymes
2. Decrease drug absorption from the GI tract
3. Alter drug binding to plasma proteins
4. Enhance drug elimination Correct Answers 1. Increase drug-
metabolizing enzymes
A medication review of an elderly person's medications
involves:
1. Asking the patient to bring a list of current prescription
medications to the visit
2. Having the patient bring all of their prescription, over-the-
counter, and herbal medications to the visit
3. Asking what other providers are writing prescriptions for
them
4. All of the above Correct Answers 4. All of the above
A number of barriers and concerns exist before the goals of a
safe and efficient information technology (IT) system can be
realized. Which of the following is NOT a barrier to adoption
and use of IT in prescribing drugs?
1. Cost of initial setup
,2. Access to highly skilled experts
3. Compatibility between systems
4. Patient confidentiality risks Correct Answers 2. Access to
highly skilled experts
A patient with a new onset of systolic ejection murmur should
be assessed for which nutritional deficiency?
1. Vitamin B12
2. Vitamin C
3. Folate
4. Niacine Correct Answers 3. Folate
A potential harmful effect on patients who take some herbal
medication is:
1. Constipation
2. Lead poisoning
3. Diarrhea
4. Life-threatening rash Correct Answers 2. Lead poisoning
A provider may consider testing for CYP2D6 variants prior to
starting tamoxifen for breast cancer to:
, 1. Ensure the patient will not have increased adverse drug
reactions to the tamoxifen
2. Identify potential drug-drug interactions that may occur with
tamoxifen
3. Reduce the likelihood of therapeutic failure with tamoxifen
treatment
4. Identify poor metabolizers of tamoxifen Correct Answers 3.
Reduce the likelihood of therapeutic failure with tamoxifen
treatment
A thorough understanding of herbs is critical to patient safety.
An example is the use of cinnamon to treat type II diabetes. It is
important the patient uses Ceylon cinnamon, as the
commercially available cassia cinnamon contains:
1. Coumadin, which may lead to bleeding problems
2. Coumarin, which can cause liver and kidney damage
3. Cinnamic aldehyde, which is toxic to the kidney
4. Cinnamate eugenol, which is toxic to the liver Correct
Answers 2. Coumarin, which can cause liver and kidney
damage
