Hemoglobin
synthesis, structure & function
,
, Introduction
• The hemoglobin are red globular proteins which
have a molecular weight of about 64,500 and
comprise almost one third of the weight of a red
cell. Their primary function is the carriage of
oxygen from the lungs to the tissues.
• Over 500 different haemoglobin variants have
been described but all share the same basic
structure of four globin polypeptide chains each
with haem group. Functional haemoglobin
composed of two pairs of dissimilar globins.
, Haemoglobin synthesis
Although haem & globin synthesis
separately within developing red cell
precursors their rate of synthesis are
carefully coordinated to ensure optimal
efficiency of haemoglobin assembly.
synthesis, structure & function
,
, Introduction
• The hemoglobin are red globular proteins which
have a molecular weight of about 64,500 and
comprise almost one third of the weight of a red
cell. Their primary function is the carriage of
oxygen from the lungs to the tissues.
• Over 500 different haemoglobin variants have
been described but all share the same basic
structure of four globin polypeptide chains each
with haem group. Functional haemoglobin
composed of two pairs of dissimilar globins.
, Haemoglobin synthesis
Although haem & globin synthesis
separately within developing red cell
precursors their rate of synthesis are
carefully coordinated to ensure optimal
efficiency of haemoglobin assembly.
