Psychopharmacology Board Review:
Substance Intoxication, Withdrawal
Management, Antidepressants, Mood
Stabilizers, Antipsychotics, EPS,
Serotonin Syndrome, and Toxicology
Study Guide Verified Questions Provided
with A+ Graded Rationales Latest
Updated 2026
• CBT
• If severe: dronabinol, gabapentin
• Sleep disturbance with sedative hypnotics (zolpidem) or BZDs
Treatment for Marijuana Withdrawal
• Supportive care; fluids
• BZDs for agitation
-Chlorpromazine (hyperemesis)
-Albuterol (bronchospasms)
Treatment for acute Marijuana toxicity
-Supportive
-Benzodiazepines
-Haloperidol
-Barbituates
-Nitroglycerin or Nitroprusside (htn)
Treatment for PCP intoxication
• Supportive care
• BZD
• Add barbiturates (seizures)
• Nitroprusside (htn)
• Cyproheptadine (SS)
• Naloxone
1|Page
, Treatment for Dextromethorphan Toxicity
Chlorpromazine
FGA for nausea and vomiting associated with opioid overdose
-Clonidine
-Lofexidine
-Buprenorphine +/- naloxone
-Methadone
-Chlorpromazine for emesis
Treatment for opioid withdrawal
• Supportive: ABCs
• Naloxone
Treatment for opioid overdose
-Supportive
-Benzodiazepines
-Diphenhydramine (for dystonia)
treatment for Ketamine toxicity
Disulfiram
treatment of alcohol use disorder (promotes abstinence), initiate 12 hours or more
after last EtOH
• Acamprosate
• Disulfiram
• Naltrexone
Treatmet for Psychological dependence of Alcohol
-Chlordiazepoxide (long acting)
-Lorazepam (short acting)
treatment for physical dependence of Alcohol
• Thiamine, folic acid, hydration, glucose, sodium
• Benzodiazepines: chlordiazepoxide; lorazepam
• Anticonvulsants (barbiturates, propofol); alpha-2 agonist (clonidine) or beta-blocker for
autonomic symptoms
Treatment for Ethanol Withdrawal
2|Page