,McCance: aQPathophysiology: aQThe aQBiologic aQBasis aQfor aQDisease aQin aQAdults aQand aQChildren aQ(8th
aQEdition) aQTEST aQBANK
CONTENTS:
Chapter aQ01: aQCellular aQBiology
Chapter aQ02: aQAltered aQCellular aQand aQTissue aQBiology: aQEnvironmental aQAgents
Chapter aQ03: aQThe aQCellular aQEnvironment: aQFluids aQand aQElectrolytes, aQAcids aQand aQBases
Chapter aQ04: aQGenes aQand aQGenetic aQDiseases
Chapter aQ05: aQGenes, aQEnvironment-Lifestyle, aQand aQCommon aQDiseases
Chapter aQ06: aQEpigenetics aQand aQDisease
Chapter aQ07: aQInnate aQImmunity: aQInflammation aQand aQWound aQHealing
Chapter aQ08: aQAdaptive aQImmunity
Chapter aQ09: aQAlterations aQin aQImmunity aQand aQInflammation
Chapter aQ10: aQInfection
Chapter aQ11: aQStress aQand aQDisease
Chapter aQ12: aQCancer aQBiology
Chapter aQ13: aQCancer aQEpidemiology
Chapter aQ14: aQCancer aQin aQChildren
Chapter aQ15: aQStructure aQand aQFunction aQof aQthe aQNeurologic aQSystem
Chapter aQ16: aQPain, aQTemperature aQRegulation, aQSleep, aQand aQSensory aQFunction
Chapter aQ17: aQAlterations aQin aQCognitive aQSystems, aQCerebral aQHemodynamics, aQand aQMotor aQFunction
Chapter aQ18: aQDisorders aQof aQthe aQCentral aQand aQPeripheral aQNervous aQSystems aQand aQthe aQNeuromuscular aQJunction
Chapter aQ19: aQNeurobiology aQof aQSchizophrenia, aQMood aQDisorders, aQand aQAnxiety aQDisorders
Chapter aQ20: aQAlterations aQof aQNeurologic aQFunction aQin aQChildren
Chapter aQ21: aQMechanisms aQof aQHormonal aQRegulation
Chapter aQ22: aQAlterations aQof aQHormonal aQRegulation
Chapter aQ23: aQObesity aQand aQDisorders aQof aQNutrition
Chapter aQ24: aQStructure aQand aQFunction aQof aQthe aQReproductive aQSystems
Chapter aQ25: aQAlterations aQof aQthe aQFemale aQReproductive aQSystem
Chapter aQ26: aQAlterations aQof aQthe aQMale aQReproductive aQSystem
Chapter aQ27: aQSexually aQTransmitted aQInfections
Chapter aQ28: aQStructure aQand aQFunction aQof aQthe aQHematologic aQSystem
Chapter aQ29: aQAlterations aQof aQErythrocytes, aQPlatelets, aQand aQHemostatic aQFunction
Chapter aQ30: aQAlterations aQof aQLeukocyte aQand aQLymphoid aQFunction
Chapter aQ31: aQAlterations aQof aQHematologic aQFunction aQin aQChildren
Chapter aQ32: aQStructure aQand aQFunction aQof aQthe aQCardiovascular aQand aQLymphatic aQSystems
Chapter aQ33: aQAlterations aQof aQCardiovascular aQFunction
Chapter aQ34: aQAlterations aQof aQCardiovascular aQFunction aQin aQChildren
Chapter aQ35: aQStructure aQand aQFunction aQof aQthe aQPulmonary aQSystem
Chapter aQ36: aQAlterations aQof aQPulmonary aQFunction
Chapter aQ37: aQAlterations aQof aQPulmonary aQFunction aQin aQChildren
Chapter aQ38: aQStructure aQand aQFunction aQof aQthe aQRenal aQand aQUrologic aQSystems
Chapter aQ39: aQAlterations aQof aQRenal aQand aQUrinary aQTract aQFunction
Chapter aQ40: aQAlterations aQof aQRenal aQand aQUrinary aQTract aQFunction aQin aQChildren
Chapter aQ41: aQStructure aQand aQFunction aQof aQthe aQDigestive aQSystem
Chapter aQ42: aQAlterations aQof aQDigestive aQFunction
Chapter aQ43: aQAlterations aQof aQDigestive aQFunction aQin aQChildren
Chapter aQ44: aQStructure aQand aQFunction aQof aQthe aQMusculoskeletal aQSystem
Chapter aQ45: aQAlterations aQof aQMusculoskeletal aQFunction
Chapter aQ46: aQAlterations aQof aQMusculoskeletal aQFunction aQin aQChildren
Chapter aQ47: aQStructure, aQFunction, aQand aQDisorders aQof aQthe aQIntegument
Chapter aQ48: aQAlterations aQof aQthe aQIntegument aQin aQChildren
Chapter aQ49: aQShock, aQMultiple aQOrgan aQDysfunction aQSyndrome, aQand aQBurns aQin aQAdults
Chapter aQ50: aQShock, aQMultiple aQOrgan aQDysfunction aQSyndrome, aQand aQBurns aQin aQChildren
, McCance: aQPathophysiology: aQThe aQBiologic aQBasis aQfor aQDisease aQin aQAdults aQand aQChildren aQ(8th aQEdition)
aQTEST aQBANK
Part aQ1: aQCENTRAL aQCONCEPTS aQOF aQPATHOPHYSIOLOGY: aQCELLS aQAND
aQTISSUES aQUnit aQI: aQTHE aQCELL
CHAPTER aQ01: aQCELLULAR aQBIOLOGY
MULTIPLE aQCHOICE
1. Which aQstatement aQbest aQdescribes aQthe aQcellular aQfunction aQof aQmetabolic aQabsorption?
a. Cells aQcan aQproduce aQproteins.
b. Cells aQcan aQsecrete aQdigestive
enzymes.
aQ
c. Cells aQcan aQtake aQin aQand aQuse
aQnutrients.
d. Cells aQcan aQsynthesize aQfats.
ANS: a Q C
In aQmetabolic aQabsorption, aQall aQcells aQtake aQin aQand aQuse aQnutrients aQand aQother aQsubstances aQfrom
aQtheir aQsurroundings. aQThe aQremaining aQoptions aQare aQnot aQinclusive aQin aQtheir aQdescriptions aQof
aQcellular aQmetabolic aQabsorption.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
2. Where aQis aQmost aQof aQa aQcell’s aQgenetic aQinformation, aQincluding aQRNA aQand aQDNA, aQcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: a Q C
The aQnucleus aQcontains aQthe aQnucleolus, aQa aQsmall aQdense aQstructure aQcomposed aQlargely aQof aQRNA,
aQmost aQof aQthe aQcellular aQDNA, aQand aQthe aQDNA-binding aQproteins, aQsuch aQas aQthe aQhistones,
aQwhich aQregulate aQits aQactivity. aQThe aQmitochondria aQare aQresponsible aQfor aQcellular aQrespiration
aQand aQenergy aQproduction.
Ribosomes’ aQchief aQfunction aQis aQto aQprovide aQsites aQfor aQcellular aQprotein aQsynthesis. aQLysosomes
aQfunction aQas aQthe aQintracellular aQdigestive aQsystem.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
3. Which aQcomponent aQof aQthe aQcell aQproduces aQhydrogen aQperoxide aQ(H2O2) aQby aQusing aQoxygen
to aQremove aQhydrogen aQatoms aQfrom aQspecific aQsubstrates aQin aQan aQoxidative aQreaction?
aQ
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: a Q B
, McCance: aQPathophysiology: aQThe aQBiologic aQBasis aQfor aQDisease aQin aQAdults aQand aQChildren aQ(8th aQEdition)
aQTEST aQBANK
Peroxisomes aQare aQso aQnamed aQbecause aQthey aQusually aQcontain aQenzymes aQthat aQuse aQoxygen aQto
aQremove aQhydrogen aQatoms aQfrom aQspecific aQsubstrates aQin aQan aQoxidative aQreaction aQthat aQproduces
aQH2O2, aQwhich aQis aQa aQpowerful aQoxidant aQand aQpotentially aQdestructive aQif aQit aQaccumulates aQor
aQescapes aQfrom aQperoxisomes.
Ribosomes aQare aQRNA-protein aQcomplexes aQ(nucleoproteins) aQthat aQare aQsynthesized aQin aQthe
aQnucleolus aQand aQsecreted aQinto aQthe aQcytoplasm aQthrough aQpores aQin aQthe aQnuclear aQenvelope
aQcalled aQnuclear aQpore aQcomplexes. aQLysosomes aQare aQsaclike aQstructures aQthat aQoriginate aQfrom
aQthe aQGolgi aQcomplex aQand aQcontain aQmore aQthan aQ40 aQdigestive aQenzymes aQcalled aQhydrolases,
aQwhich aQcatalyze aQbonds aQin aQproteins, aQlipids, aQnucleic aQacids, aQand aQcarbohydrates. aQAn
aQendosome aQis aQa aQvesical aQthat aQhas aQbeen aQpinched aQoff aQfrom aQthe aQcellular aQmembrane.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
4. Which aQcell aQcomponent aQis aQcapable aQof aQcellular aQautodigestion aQwhen aQit aQis aQreleased aQduring aQcell
aQinjury?
a. Ribosome
b. Golgi aQcomplex
c. Smooth aQendoplasmic
reticulum
aQ
d. Lysosomes
ANS: a Q D
The aQlysosomal aQmembrane aQacts aQas aQa aQprotective aQshield aQbetween aQthe aQpowerful aQdigestive
aQenzymes aQwithin aQthe aQlysosome aQand aQthe aQcytoplasm, aQpreventing aQtheir aQleakage aQinto aQthe
aQcytoplasmic aQmatrix. aQDisruption aQof aQthe aQmembrane aQby aQvarious aQtreatments aQor aQcellular
aQinjury aQleads aQto aQa aQrelease aQof aQthe aQlysosomal aQenzymes, aQwhich aQcan aQthen aQreact aQwith aQtheir
aQspecific aQsubstrates, aQcausing aQcellular aQself- aQdigestion. aQThe aQchief aQfunction aQof aQa aQribosome
aQis aQto aQprovide aQsites aQfor aQcellular aQprotein aQsynthesis. aQThe aQGolgi aQcomplex aQis aQa aQnetwork aQof
aQflattened, aQsmooth aQvesicles aQand aQmembranes aQoften aQlocated aQnear aQthe aQcell aQnucleus. aQThe
aQsmooth aQendoplasmic aQreticulum aQis aQinvolved aQin aQsteroid aQhormone aQproduction aQand
aQremoving aQtoxic aQsubstances aQfrom aQthe aQcell.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
5. Which aQcAMP-mediated aQresponse aQis aQrelated aQto aQantidiuretic aQhormone?
a. Increased aQheart aQrate aQand aQforce aQof
aQ contraction
b. Secretion aQof aQcortisol
c. Increased aQretention aQof aQwater
d. Breakdown aQof aQfat
ANS: a Q C
Antidiuretic aQhormone aQleads aQto aQincreased aQretention aQof aQwater aQin aQthe aQbody. aQEpinephrine
aQcauses aQincreases aQin aQheart aQrate aQand aQforce aQof aQcontraction. aQIncreased aQcortisol aQsecretion aQis
aQdue aQto aQACTH. aQBreakdown aQof aQfat aQis aQdue aQto aQglucagon.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
6. During aQwhich aQphase aQof aQthe aQcell aQcycle aQis aQDNA aQsynthesized?
a. G1
b. S
c. G2
d. M
aQEdition) aQTEST aQBANK
CONTENTS:
Chapter aQ01: aQCellular aQBiology
Chapter aQ02: aQAltered aQCellular aQand aQTissue aQBiology: aQEnvironmental aQAgents
Chapter aQ03: aQThe aQCellular aQEnvironment: aQFluids aQand aQElectrolytes, aQAcids aQand aQBases
Chapter aQ04: aQGenes aQand aQGenetic aQDiseases
Chapter aQ05: aQGenes, aQEnvironment-Lifestyle, aQand aQCommon aQDiseases
Chapter aQ06: aQEpigenetics aQand aQDisease
Chapter aQ07: aQInnate aQImmunity: aQInflammation aQand aQWound aQHealing
Chapter aQ08: aQAdaptive aQImmunity
Chapter aQ09: aQAlterations aQin aQImmunity aQand aQInflammation
Chapter aQ10: aQInfection
Chapter aQ11: aQStress aQand aQDisease
Chapter aQ12: aQCancer aQBiology
Chapter aQ13: aQCancer aQEpidemiology
Chapter aQ14: aQCancer aQin aQChildren
Chapter aQ15: aQStructure aQand aQFunction aQof aQthe aQNeurologic aQSystem
Chapter aQ16: aQPain, aQTemperature aQRegulation, aQSleep, aQand aQSensory aQFunction
Chapter aQ17: aQAlterations aQin aQCognitive aQSystems, aQCerebral aQHemodynamics, aQand aQMotor aQFunction
Chapter aQ18: aQDisorders aQof aQthe aQCentral aQand aQPeripheral aQNervous aQSystems aQand aQthe aQNeuromuscular aQJunction
Chapter aQ19: aQNeurobiology aQof aQSchizophrenia, aQMood aQDisorders, aQand aQAnxiety aQDisorders
Chapter aQ20: aQAlterations aQof aQNeurologic aQFunction aQin aQChildren
Chapter aQ21: aQMechanisms aQof aQHormonal aQRegulation
Chapter aQ22: aQAlterations aQof aQHormonal aQRegulation
Chapter aQ23: aQObesity aQand aQDisorders aQof aQNutrition
Chapter aQ24: aQStructure aQand aQFunction aQof aQthe aQReproductive aQSystems
Chapter aQ25: aQAlterations aQof aQthe aQFemale aQReproductive aQSystem
Chapter aQ26: aQAlterations aQof aQthe aQMale aQReproductive aQSystem
Chapter aQ27: aQSexually aQTransmitted aQInfections
Chapter aQ28: aQStructure aQand aQFunction aQof aQthe aQHematologic aQSystem
Chapter aQ29: aQAlterations aQof aQErythrocytes, aQPlatelets, aQand aQHemostatic aQFunction
Chapter aQ30: aQAlterations aQof aQLeukocyte aQand aQLymphoid aQFunction
Chapter aQ31: aQAlterations aQof aQHematologic aQFunction aQin aQChildren
Chapter aQ32: aQStructure aQand aQFunction aQof aQthe aQCardiovascular aQand aQLymphatic aQSystems
Chapter aQ33: aQAlterations aQof aQCardiovascular aQFunction
Chapter aQ34: aQAlterations aQof aQCardiovascular aQFunction aQin aQChildren
Chapter aQ35: aQStructure aQand aQFunction aQof aQthe aQPulmonary aQSystem
Chapter aQ36: aQAlterations aQof aQPulmonary aQFunction
Chapter aQ37: aQAlterations aQof aQPulmonary aQFunction aQin aQChildren
Chapter aQ38: aQStructure aQand aQFunction aQof aQthe aQRenal aQand aQUrologic aQSystems
Chapter aQ39: aQAlterations aQof aQRenal aQand aQUrinary aQTract aQFunction
Chapter aQ40: aQAlterations aQof aQRenal aQand aQUrinary aQTract aQFunction aQin aQChildren
Chapter aQ41: aQStructure aQand aQFunction aQof aQthe aQDigestive aQSystem
Chapter aQ42: aQAlterations aQof aQDigestive aQFunction
Chapter aQ43: aQAlterations aQof aQDigestive aQFunction aQin aQChildren
Chapter aQ44: aQStructure aQand aQFunction aQof aQthe aQMusculoskeletal aQSystem
Chapter aQ45: aQAlterations aQof aQMusculoskeletal aQFunction
Chapter aQ46: aQAlterations aQof aQMusculoskeletal aQFunction aQin aQChildren
Chapter aQ47: aQStructure, aQFunction, aQand aQDisorders aQof aQthe aQIntegument
Chapter aQ48: aQAlterations aQof aQthe aQIntegument aQin aQChildren
Chapter aQ49: aQShock, aQMultiple aQOrgan aQDysfunction aQSyndrome, aQand aQBurns aQin aQAdults
Chapter aQ50: aQShock, aQMultiple aQOrgan aQDysfunction aQSyndrome, aQand aQBurns aQin aQChildren
, McCance: aQPathophysiology: aQThe aQBiologic aQBasis aQfor aQDisease aQin aQAdults aQand aQChildren aQ(8th aQEdition)
aQTEST aQBANK
Part aQ1: aQCENTRAL aQCONCEPTS aQOF aQPATHOPHYSIOLOGY: aQCELLS aQAND
aQTISSUES aQUnit aQI: aQTHE aQCELL
CHAPTER aQ01: aQCELLULAR aQBIOLOGY
MULTIPLE aQCHOICE
1. Which aQstatement aQbest aQdescribes aQthe aQcellular aQfunction aQof aQmetabolic aQabsorption?
a. Cells aQcan aQproduce aQproteins.
b. Cells aQcan aQsecrete aQdigestive
enzymes.
aQ
c. Cells aQcan aQtake aQin aQand aQuse
aQnutrients.
d. Cells aQcan aQsynthesize aQfats.
ANS: a Q C
In aQmetabolic aQabsorption, aQall aQcells aQtake aQin aQand aQuse aQnutrients aQand aQother aQsubstances aQfrom
aQtheir aQsurroundings. aQThe aQremaining aQoptions aQare aQnot aQinclusive aQin aQtheir aQdescriptions aQof
aQcellular aQmetabolic aQabsorption.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
2. Where aQis aQmost aQof aQa aQcell’s aQgenetic aQinformation, aQincluding aQRNA aQand aQDNA, aQcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: a Q C
The aQnucleus aQcontains aQthe aQnucleolus, aQa aQsmall aQdense aQstructure aQcomposed aQlargely aQof aQRNA,
aQmost aQof aQthe aQcellular aQDNA, aQand aQthe aQDNA-binding aQproteins, aQsuch aQas aQthe aQhistones,
aQwhich aQregulate aQits aQactivity. aQThe aQmitochondria aQare aQresponsible aQfor aQcellular aQrespiration
aQand aQenergy aQproduction.
Ribosomes’ aQchief aQfunction aQis aQto aQprovide aQsites aQfor aQcellular aQprotein aQsynthesis. aQLysosomes
aQfunction aQas aQthe aQintracellular aQdigestive aQsystem.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
3. Which aQcomponent aQof aQthe aQcell aQproduces aQhydrogen aQperoxide aQ(H2O2) aQby aQusing aQoxygen
to aQremove aQhydrogen aQatoms aQfrom aQspecific aQsubstrates aQin aQan aQoxidative aQreaction?
aQ
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: a Q B
, McCance: aQPathophysiology: aQThe aQBiologic aQBasis aQfor aQDisease aQin aQAdults aQand aQChildren aQ(8th aQEdition)
aQTEST aQBANK
Peroxisomes aQare aQso aQnamed aQbecause aQthey aQusually aQcontain aQenzymes aQthat aQuse aQoxygen aQto
aQremove aQhydrogen aQatoms aQfrom aQspecific aQsubstrates aQin aQan aQoxidative aQreaction aQthat aQproduces
aQH2O2, aQwhich aQis aQa aQpowerful aQoxidant aQand aQpotentially aQdestructive aQif aQit aQaccumulates aQor
aQescapes aQfrom aQperoxisomes.
Ribosomes aQare aQRNA-protein aQcomplexes aQ(nucleoproteins) aQthat aQare aQsynthesized aQin aQthe
aQnucleolus aQand aQsecreted aQinto aQthe aQcytoplasm aQthrough aQpores aQin aQthe aQnuclear aQenvelope
aQcalled aQnuclear aQpore aQcomplexes. aQLysosomes aQare aQsaclike aQstructures aQthat aQoriginate aQfrom
aQthe aQGolgi aQcomplex aQand aQcontain aQmore aQthan aQ40 aQdigestive aQenzymes aQcalled aQhydrolases,
aQwhich aQcatalyze aQbonds aQin aQproteins, aQlipids, aQnucleic aQacids, aQand aQcarbohydrates. aQAn
aQendosome aQis aQa aQvesical aQthat aQhas aQbeen aQpinched aQoff aQfrom aQthe aQcellular aQmembrane.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
4. Which aQcell aQcomponent aQis aQcapable aQof aQcellular aQautodigestion aQwhen aQit aQis aQreleased aQduring aQcell
aQinjury?
a. Ribosome
b. Golgi aQcomplex
c. Smooth aQendoplasmic
reticulum
aQ
d. Lysosomes
ANS: a Q D
The aQlysosomal aQmembrane aQacts aQas aQa aQprotective aQshield aQbetween aQthe aQpowerful aQdigestive
aQenzymes aQwithin aQthe aQlysosome aQand aQthe aQcytoplasm, aQpreventing aQtheir aQleakage aQinto aQthe
aQcytoplasmic aQmatrix. aQDisruption aQof aQthe aQmembrane aQby aQvarious aQtreatments aQor aQcellular
aQinjury aQleads aQto aQa aQrelease aQof aQthe aQlysosomal aQenzymes, aQwhich aQcan aQthen aQreact aQwith aQtheir
aQspecific aQsubstrates, aQcausing aQcellular aQself- aQdigestion. aQThe aQchief aQfunction aQof aQa aQribosome
aQis aQto aQprovide aQsites aQfor aQcellular aQprotein aQsynthesis. aQThe aQGolgi aQcomplex aQis aQa aQnetwork aQof
aQflattened, aQsmooth aQvesicles aQand aQmembranes aQoften aQlocated aQnear aQthe aQcell aQnucleus. aQThe
aQsmooth aQendoplasmic aQreticulum aQis aQinvolved aQin aQsteroid aQhormone aQproduction aQand
aQremoving aQtoxic aQsubstances aQfrom aQthe aQcell.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
5. Which aQcAMP-mediated aQresponse aQis aQrelated aQto aQantidiuretic aQhormone?
a. Increased aQheart aQrate aQand aQforce aQof
aQ contraction
b. Secretion aQof aQcortisol
c. Increased aQretention aQof aQwater
d. Breakdown aQof aQfat
ANS: a Q C
Antidiuretic aQhormone aQleads aQto aQincreased aQretention aQof aQwater aQin aQthe aQbody. aQEpinephrine
aQcauses aQincreases aQin aQheart aQrate aQand aQforce aQof aQcontraction. aQIncreased aQcortisol aQsecretion aQis
aQdue aQto aQACTH. aQBreakdown aQof aQfat aQis aQdue aQto aQglucagon.
PTS: a Q aQ 1 DIF: Cognitive aQLevel: aQRemembering
6. During aQwhich aQphase aQof aQthe aQcell aQcycle aQis aQDNA aQsynthesized?
a. G1
b. S
c. G2
d. M
