COMPLETE QUESTIONS AND SOLUTIONS
◉ lichenification. Answer: area of increased epidermal thickening
with exaggerated skin markings, caused by constant rubbing (atopic
eczema)
◉ keloid. Answer: a sharply elevated, irregularly shaped,
progressively enlarging scar due to excessive collagen formation in
the dermis during connective tissue
◉ macule. Answer: flat, colored spot on the skin
◉ nodule. Answer: circumscribed, palpable area of the skin that is
>0.5 cm in diameter and appears in part or wholly within the dermis
◉ papule. Answer: A circumscribed, solid elevation of skin < 1cm in
diameter, with no visible fluid
◉ patch. Answer: large macule, >2cm in diameter
◉ plaque. Answer: circumscribed, disk-shaped elevated area of the
skin >1cm diameter
,◉ purpura. Answer: multiple pinpoint hemorrhages and
accumulation of blood under the skin
◉ pustule. Answer: raised spot on the skin containing pus
◉ scales. Answer: flakes or dry patches made up of excess dead
epidermal cells
◉ scar. Answer: area of fibrous tissue that replaces the lost
epidermis
◉ stria. Answer: streak-like, linear, atrophic, pink, purple, or white
lesion caused by stretching of the skin
◉ Telangiectasia. Answer: skin lesion due to permanently enlarged
and dilated blood vessels that are visible
◉ ulcer. Answer: loss of epidermis and part or whole of the dermis
◉ vesicle. Answer: visible accumulation of fluid beneath the
epidermis (<0.5 cm in diameter)
, ◉ weal. Answer: circumscribed, elevated area of cutaneous edema
◉ Dermatitis Medicamentosa. Answer: Hypersensitivity reaction to
a drug.
onset is abrupt, widespread, and symmetric erythematous eruption
◉ type 1: immediate-type immunologic reaction. Answer: IgE
mediated
manifested by urticaria and angioedema of skin or mucosa, edema of
other organ, and fall in BP (anaphylatic shock)
◉ Type 2: Cytotoxic reaction. Answer: drug or causative agent
causes lysis of cells, such as platelets or leukocytes, or may, by
combo with another drug, produce antibodies (immune complexes)
that causes lysis or phagocytosis
◉ type 3: serum sickness, drug-induced vasculitis. Answer: IgG and
IgM antibodies are formed against a drug
manifested by vasculitis, urticaria-like lesions, arthritis, nephritis,
alveolitis, hemolytic anemia, thrombocytopenia, and agranulocytosis
◉ type 4: morbilliform (exanthematous) reaction. Answer: cell-
mediated immune reaction