QUESTIONS WITH ANSWERS GRADED A+
◉ Strep gram stain? Answer: chains or in pairs, gram positive cocci
◉ autoimmune disease by drugs or disease triggers (EBV), UV light, or
estrogen? Answer: Systemic Lupus Erythematosus (SLE)
◉ autoantibodies cause damage to tissue/organs, deficient complement
3&4? Answer: SLE
◉ common initial complaint of SLE? Answer: arthralgias
◉ skin and kidney characteristics of SLE? Answer: Butterfly shaped,
malar rash on face, kidney most common affected organ-
glomerulonephritis
◉ ANA? Answer: antinuclear antibody- detects autoantibodies; positive
in SLE
◉ anti-dsDNA? Answer: >25 during SLE exacerbation
, ◉ Treatment of SLE? Answer: Methylprednisolone IV in severe case,
Prednisone for maintenance or mild flares
◉ triggers SLE exacerbation? Answer: Sulfa and UV light
◉ baseline ophthalmologic exam prior to ordering? Answer:
Hydroxychloroquine for SLE
◉ perioperative in SLE? Answer: Continue meds if severe SLE, hold for
1 week if not severe for THA or TKA
◉ localized swelling of skin and mucous tissues? Answer: Angioedema
◉ Mast cell mediated rxn Angioedema? Answer: accompanied by
urticaria and pruritus; Tx with antihistamines and glucocorticoids
◉ Bradykinin mediated rxn Angioedema? Answer: doesn't involve
histamine; from ACE inhibitors
◉ anaphylaxis Answer: usually includes urticaria or angioedema; airway
obstruction