MEDICATIONS FOR HYPERTENSIVE CRISIS
(Pharm ATI) Exam Questions and Correct Answers
1. Select Prototype Medication answer: answer: Nitroprusside (Nitropress), a centrally
acting vasodilator
2. Other Medications answer: answer: -Nitroglycerin (Nitrostat IV)= vasodilator
-Nicardipine (Cardene)= calcium channel blocker
-Clevidipine (Cleviprex)= calcium channel blocker
-Enalaprilat (Vasotec IV)= ACE inhibitor
-Esmolol HCL (Brevibloc)= ACE inhibitor
3. Nitroprusside answer: Nitropress
4. Nitroglycerin answer: Nitrostat IV
5. Nicardipine answer: Cardene
6. Clevidipine answer: Cleviprex
7. Enalaprilat answer: Vasotec IV
8. Esmolol HCL answer: Brevibloc
9. Expected Pharmacological Action answer: answer: Direct vasodilation of arteries and
veins resulting in rapid
reduction of BP (decreased preload and after load)
10. Therapeutic Uses answer: answer: Hypertensive Crisis
11. Adverse Effects answer: answer: -Excessive hypotensive
-Cyanide poisoning (headache drowsniess, and may lead to cardiac arrest)
-Thiocyanate toxicity (CNS findings, including delirium, psychosis)-- accumulates when nitroprusside is given
over several days
12. Excessive hypotensive Interventions answer: answer: -Administer medication
slowly because rapid administra-
tion will cause BP to go down rapidly
-Monitor the client's BP and ECG
-Keep client supine during administration
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