ATI Pharmacology Medications Affecting Blood
Pressure Exam Questions and Correct Answers
1. The classifications of medications used to control blood pressure
include answers answer: answers answer: -
Thiazide diuretics (often the first medication given for hypertension)
-Angiotensin-converting enzyme (ACE) inhibitors
-Angiotensin II receptor blockers (ARBs)
-Aldosterone antagonists
-Direct renin inhibitors
-Calcium channel blockers (CCB)
-Alpha adrenergic blockers
-Centrally acting alpha2 agonists
-Beta adrenergic blockers
-Vasodilators
2. Angiotensin-Converting Enzyme (ACE) Inhibitors answers answer:
captopril (Capoten)
ÏOÏ ther Medications answers answer:
-Enalapril (Vasotec)
-Enalaprilat (Vasotec intravenous)
-Fosinopril (Monopril)
-Lisinopril (Prinivil)
-Ramipril (Altace)
-Moexipril (Univasc)
3. ACE inhibitors actions answers answer: ACE inhibitors produce their ettects by blocking the
conversion of angiotensin I to angiotensin II,
leading to answers answer:
Vasodilation (mostly arteriole).
Excretion of sodium and water, and retention of potassium by actions in the
kidneys. Reduction in pathological changes in the blood vessels and heart that
result from the presence of angiotensin II and aldosterone.
,4. ACE inhibitors uses answers answer: - Hypertension
-Heart failure
-Myocardial infarction (to decrease mortality and to decrease risk of heart failure and left ventricular
dysfunction)
-Diabetic and nondiabetic nephropathy
-For clients at high risk for a cardiovascular event, ramipril can be used to prevent MI, stroke, or death.
, 5. ACEI Adverse Effects answers answer: 1. First-dose orthostatic hypotension.
-> If patient is taking diuretic, stop 2-3 days before starting ACEI
2. Cough related to inhibition of kinase II (alternative name for ACE), which
results in increase in bradykinin.
-> Expected, but need to stop
3. Hyperkalemia
4. Rash and dysgeusia (altered taste),
primarily with captopril
5. ANGIOEDEMA
6. Neutropenia (rare but serious complication of captopril)
6. ANGIOEDEMA- what is that? what the nurse needs need to intervent?
answers answer: Give SUBQ EPINEPHRINE
swelling of tongue and pharynx
7. How often a person taking ACEI need to monitor WBC level? answers
answer: Monitor the client's WBC counts every 2 weeks for 3 months, then periodically.
8. ACEI- contraindications for answers answer: 1. Pregnancy Risk Category D
2. Contraindicated in clients who have history of allergy/angioedema to ACE inhibitors,
in bilateral renal artery stenosis, or in clients who have a single kidney.
3. Use cautiously in clients who have renal impairment and collagen vascular disease because they are
at greater risk for developing neutropenia. Closely monitor these clients for signs of infection.
9. ACEI interactions with answers answer: 1. First dose hypotension if taken with diuretics
2. Additive hypotensive ettects
3. Potassium supplements and potassium-
sparing diuretics increase the risk of
hyperkalemia.
4. NSAID- decreased HYPOTENSIVE EFFECT
5. Lithium toxicity
10. enalaprilat route of administration answers answer: This is the only ACEI
available for IV Use
11. ACEI can be given/ combination
with diuretic answers answer: thiazide
12. captopril and moexipril
Pressure Exam Questions and Correct Answers
1. The classifications of medications used to control blood pressure
include answers answer: answers answer: -
Thiazide diuretics (often the first medication given for hypertension)
-Angiotensin-converting enzyme (ACE) inhibitors
-Angiotensin II receptor blockers (ARBs)
-Aldosterone antagonists
-Direct renin inhibitors
-Calcium channel blockers (CCB)
-Alpha adrenergic blockers
-Centrally acting alpha2 agonists
-Beta adrenergic blockers
-Vasodilators
2. Angiotensin-Converting Enzyme (ACE) Inhibitors answers answer:
captopril (Capoten)
ÏOÏ ther Medications answers answer:
-Enalapril (Vasotec)
-Enalaprilat (Vasotec intravenous)
-Fosinopril (Monopril)
-Lisinopril (Prinivil)
-Ramipril (Altace)
-Moexipril (Univasc)
3. ACE inhibitors actions answers answer: ACE inhibitors produce their ettects by blocking the
conversion of angiotensin I to angiotensin II,
leading to answers answer:
Vasodilation (mostly arteriole).
Excretion of sodium and water, and retention of potassium by actions in the
kidneys. Reduction in pathological changes in the blood vessels and heart that
result from the presence of angiotensin II and aldosterone.
,4. ACE inhibitors uses answers answer: - Hypertension
-Heart failure
-Myocardial infarction (to decrease mortality and to decrease risk of heart failure and left ventricular
dysfunction)
-Diabetic and nondiabetic nephropathy
-For clients at high risk for a cardiovascular event, ramipril can be used to prevent MI, stroke, or death.
, 5. ACEI Adverse Effects answers answer: 1. First-dose orthostatic hypotension.
-> If patient is taking diuretic, stop 2-3 days before starting ACEI
2. Cough related to inhibition of kinase II (alternative name for ACE), which
results in increase in bradykinin.
-> Expected, but need to stop
3. Hyperkalemia
4. Rash and dysgeusia (altered taste),
primarily with captopril
5. ANGIOEDEMA
6. Neutropenia (rare but serious complication of captopril)
6. ANGIOEDEMA- what is that? what the nurse needs need to intervent?
answers answer: Give SUBQ EPINEPHRINE
swelling of tongue and pharynx
7. How often a person taking ACEI need to monitor WBC level? answers
answer: Monitor the client's WBC counts every 2 weeks for 3 months, then periodically.
8. ACEI- contraindications for answers answer: 1. Pregnancy Risk Category D
2. Contraindicated in clients who have history of allergy/angioedema to ACE inhibitors,
in bilateral renal artery stenosis, or in clients who have a single kidney.
3. Use cautiously in clients who have renal impairment and collagen vascular disease because they are
at greater risk for developing neutropenia. Closely monitor these clients for signs of infection.
9. ACEI interactions with answers answer: 1. First dose hypotension if taken with diuretics
2. Additive hypotensive ettects
3. Potassium supplements and potassium-
sparing diuretics increase the risk of
hyperkalemia.
4. NSAID- decreased HYPOTENSIVE EFFECT
5. Lithium toxicity
10. enalaprilat route of administration answers answer: This is the only ACEI
available for IV Use
11. ACEI can be given/ combination
with diuretic answers answer: thiazide
12. captopril and moexipril
