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BIOS 242 Exam 3 2026 – Immunity, Infectious Diseases & Host Defenses | 180+ Questions

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This BIOS 242 Exam 3 Compressed 2026 study guide contains 180+ verified exam questions and answers covering innate immunity, adaptive immunity, infectious diseases, and pathogen-specific case studies. The document provides a structured review of first, second, and third lines of defense, including physical barriers, inflammation, phagocytosis, complement system, B and T lymphocytes, antibodies, cytokines, and antigen presentation. It also outlines the seven steps of phagocytosis, PAMPs and PRRs, interferons, membrane attack complex (MAC), and antibody classifications (IgA, IgD, IgE, IgG, IgM). The material includes detailed breakdowns of immune cell functions such as neutrophils, eosinophils, basophils, mast cells, APCs, and mechanisms of natural and artificial immunity (active and passive). It further integrates applied clinical microbiology by reviewing causes, symptoms, transmission, fatality rates, and treatments for a wide range of infectious diseases, including necrotizing fasciitis, chickenpox, shingles, smallpox, measles, rubella, meningitis, rabies, tetanus, wound botulism, sepsis, COVID-19, tuberculosis, HIV, influenza, Lyme disease, Clostridioides difficile infection, syphilis, and more. This document is highly suitable for: Pre-nursing students in Microbiology (BIOS 242) Allied health and pre-med students Biology majors studying Immunology and Infectious Disease Students preparing for cumulative microbiology exams Nursing students reviewing immune response and pathogen mechanisms It is especially relevant for courses such as: Microbiology for Health Sciences General Microbiology Human Immunology Pathogenic Microbiology Infectious Disease Host-Pathogen Interactions The comprehensive Q&A format supports rapid recall, exam readiness, and reinforcement of immune mechanisms, antibody structure and function, disease transmission pathways, and treatment protocols frequently tested in microbiology and health science examinations. Keywords: innate immunity, adaptive immunity, first line of defense, second line of defense, third line of defense, phagocytosis steps, PAMP, PRR, complement system, membrane attack complex, antibodies IgA IgD IgE IgG IgM, monomer dimer pentamer antibodies, cytokines, interferons, antigen presenting cells, natural active immunity, artificial passive immunity, necrotizing fasciitis, measles virus, rubella virus, meningitis bacteria, rabies virus, tetanus toxin, botulism toxin, sepsis septicemia, COVID 19 SARS CoV 2, tuberculosis Mycobacterium, HIV infection, influenza virus, Lyme disease Borrelia, Clostridioides difficile, syphilis Treponema pallidum, microbiology exam review

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BIOS 242 Exam 3 Compressed
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what are examples of second line of denfese? - 🧠 ANSWER

✔✔phagocytosis, inflammation, fever, antimicrobial products


What are examples of third line of defense? - 🧠 ANSWER ✔✔B and T cells


classify the elements of the first line of defense - 🧠 ANSWER ✔✔Cilia, ear

wax, skin, mucus, lactoferrin, tears

,classify the elements of the second line of defense - 🧠 ANSWER

✔✔inflammation, lysosomes, phagocytosis, phagolysosome, complement


classify the elements of the third line of defense - 🧠 ANSWER ✔✔B cells,

antibodies, plasma cells

what are the appearance and functions of neutrophils? - 🧠 ANSWER

✔✔phagocytic, found in blood, first to respond, increase during bacterial

infections

what are the appearance and functions of Eosinophils? - 🧠 ANSWER

✔✔Active in protozoal, helminth reactions, usually found in low numbers,

elevated in allergic reactions

what are the appearance and functions of Basophils? - 🧠 ANSWER

✔✔function in inflammatory events, usually found in low numbers


what are the appearance and functions of mast cells? - 🧠 ANSWER

✔✔found in the tissues, similar to basophils, contain histamines


What are the 7 steps of phagocytosis? - 🧠 ANSWER ✔✔chemotaxis,

adhesion, engulfment, phagosome, phagolysosome formation, destruction,

residual release and presents to T cells

, What is Chemotaxis? - 🧠 ANSWER ✔✔phagocytes moves to site of injury

following trails of chemicals released by damaged tissues


What is Adhesion - 🧠 ANSWER ✔✔PAMPs are going to be recognized by

PRRs on host and attach to bacterial cell


PAMP - 🧠 ANSWER ✔✔pathogen associated molecular patterns


examples of PAMP - 🧠 ANSWER ✔✔peptidoglycan, bacterial flagella,

lipopolysaccharides, and techoic acid


PRRs - 🧠 ANSWER ✔✔pattern recognition receptors used by host cells to

recognize PAMPs


engulfment - 🧠 ANSWER ✔✔cell is going to engulf the bacteria into a

phagocytic vesicle


phagosome - 🧠 ANSWER ✔✔once engulfment is complete itforms

phagosome


phagolysosome - 🧠 ANSWER ✔✔host lysosome attach to the phagosome


destruction - 🧠 ANSWER ✔✔enzymes and reactive oxygen products are

released in to vacuole killing the bacterial cells inside



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