NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY
MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM
SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
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Terms in this set (174)
Serotonin regulates Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT SSRIs
and inhibits them from reuptake of serotonin to increase
levels in the synaptic cleft to bind with postsysnaptic
5HT2 receptors
First line therapy for MDD due to milder side effect SSRIs
profiles
Six Common SSRIs citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs 4-6 weeks
, In addition to MDD, SSRIs also treat Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under suicidal ideation
age 25 years old
Life threatening adverse effect of SSRIs, especially when Serotonin Syndrome
used in combination with other serotonergic drugs
(SNRIs, TCAs, MAOIs, etc.)
Excess accumulation of serotonin resulting in Serotonin Syndrome
overstimulation of the nervous system
Seven symptoms of Serotonin Syndrome Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by blocking 5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common Irritability, headaches, and insomnia
symptoms of withdrawal include
Medicine specific side effect of citalopram Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations Paroxetine
with congenital heart defects
All SSRIs but paroxetine (D) are pregnancy category C
Three SSRIs that are inhibitors of Cytochrome P450 fluoxetine, fluvoxamine, and paroxetine
enzymes
Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding SNRIs
to presynaptic SERT and NET to inhibit them from
reuptake of serotonin and norepinephrine to increase
their levels in the synaptic cleft
In addition to MDD SNRIs treat Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes
Six common side effects of SNRIs include: Insomnia, nausea, sexual dysfunction, hypertension, sweating, headaches
MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM
SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Leave the first rating
Save
Students also studied
Maryville Psychopharmacology, Exa... BARKLEY PMHNP Pract.. ONE EXA... CMN 548 Final Exam Study Guide O... NUR 32
Teacher 98 terms Teacher 87 terms Teacher 150 terms Teacher
We_Julius Preview mathewmwai01 Preview Raz_Tar8 Preview Spe
Practice questions for this set
Learn 1 /7 Study with Learn
Terms in this set (174)
Serotonin regulates Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT SSRIs
and inhibits them from reuptake of serotonin to increase
levels in the synaptic cleft to bind with postsysnaptic
5HT2 receptors
First line therapy for MDD due to milder side effect SSRIs
profiles
Six Common SSRIs citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs 4-6 weeks
, In addition to MDD, SSRIs also treat Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under suicidal ideation
age 25 years old
Life threatening adverse effect of SSRIs, especially when Serotonin Syndrome
used in combination with other serotonergic drugs
(SNRIs, TCAs, MAOIs, etc.)
Excess accumulation of serotonin resulting in Serotonin Syndrome
overstimulation of the nervous system
Seven symptoms of Serotonin Syndrome Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by blocking 5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common Irritability, headaches, and insomnia
symptoms of withdrawal include
Medicine specific side effect of citalopram Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations Paroxetine
with congenital heart defects
All SSRIs but paroxetine (D) are pregnancy category C
Three SSRIs that are inhibitors of Cytochrome P450 fluoxetine, fluvoxamine, and paroxetine
enzymes
Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding SNRIs
to presynaptic SERT and NET to inhibit them from
reuptake of serotonin and norepinephrine to increase
their levels in the synaptic cleft
In addition to MDD SNRIs treat Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes
Six common side effects of SNRIs include: Insomnia, nausea, sexual dysfunction, hypertension, sweating, headaches
