Chikungunya.
Hector: aedes aegypti (daytime)
Transmission cycle.
Sylvan/jungle
Urban Cycle
cycle
human 2 necks
Monkeys I forest species
of aedes.
Clinical manifestation
Incubation period-a-days
acute stage
- arthritis-poly articular,migratory,edematous
(small joints wrists dangles)
- headache
- musclepain
teno synovitis/most illiform skip
, Chik sign-brown nose appearance (Rare)
hyperpigmentation over centro facial area.
chronic stage
joint pain-lasts for month.
Lab diagnosis
1) dival Isolation
mosquito cell line (1-a whs)-early diagnosis
2) Scrum bodydetection
IgM appears after redays Ilasts 3 months
Igh appears later ◦ lasts for years
- MAC ELVA
gal. sensitivity 298)-specificity.
3) Molecular method
RT-PCR- to detect specific genes Caspi, nSP4)
Hector: aedes aegypti (daytime)
Transmission cycle.
Sylvan/jungle
Urban Cycle
cycle
human 2 necks
Monkeys I forest species
of aedes.
Clinical manifestation
Incubation period-a-days
acute stage
- arthritis-poly articular,migratory,edematous
(small joints wrists dangles)
- headache
- musclepain
teno synovitis/most illiform skip
, Chik sign-brown nose appearance (Rare)
hyperpigmentation over centro facial area.
chronic stage
joint pain-lasts for month.
Lab diagnosis
1) dival Isolation
mosquito cell line (1-a whs)-early diagnosis
2) Scrum bodydetection
IgM appears after redays Ilasts 3 months
Igh appears later ◦ lasts for years
- MAC ELVA
gal. sensitivity 298)-specificity.
3) Molecular method
RT-PCR- to detect specific genes Caspi, nSP4)
