Pediatric Nursing NCLEX-RN Practice Questions & Answers
(2025–2026 Edition)
Exam
his Pediatric Nursing NCLEX-RN preparation resource is aligned with the 2025–2026
NCLEX-RN® Test Plan and focuses on comprehensive pediatric nursing care a cross
developmental stages. Core domains include growth and development from infancy
through adolescence, pediatric assessment techniques, common childhood illnesses,
congenital conditions, pediatric pharmacology, family-centered care, child safety and
injury prevention, immunizations, and nutrition. Additional emphasis includes care of the
hospitalized child, pediatric emergencies, recognition and reporting of child abuse,
chronic conditions, developmental disabilities, psychosocial considerations, and end-of-
life care in pediatric populations. Content is structured to strengthen clinical judgment,
prioritization, and safe nursing interventions consistent with NCLEX-style questioning.
Designed to reinforce pediatric competency and support readiness for licensure-level
testing
Stimulants - ✔✔✔ANSW✔✔..Medication class used to treat ADHD
(methylphenidate, amphetamines) - increase dopamine/norepinephrine for
attention control.
Autism Spectrum Disorder (ASD) - ✔✔✔ANSW✔✔..Condition indicated by lack of
eye contact, repetitive behavior, and impaired social functioning - hallmark triad of
symptoms.
Growth monitoring in ADHD medications - ✔✔✔ANSW✔✔..Monitor
height/weight, vital signs (HR/BP), appetite - stimulants can suppress growth and
elevate vital signs.
Closed comedone - ✔✔✔ANSW✔✔..A whitehead - blocked pore with oil/bacteria
trapped beneath intact skin surface.
,Benzoyl peroxide - ✔✔✔ANSW✔✔..Topical acne treatment that bleaches fabrics
- oxidizing agent that permanently discolors sheets, towels, clothes.
Isotretinoin (Accutane) teaching - ✔✔✔ANSW✔✔..Severe teratogen—requires
two forms of birth control starting 1 month before, during, and 1 month after
treatment - mandatory iPLEDGE program, monthly negative pregnancy tests.
Acute glomerulonephritis common infection - ✔✔✔ANSW✔✔..Commonly follows
streptococcal infection (group A strep).
Cola-colored urine - ✔✔✔ANSW✔✔..Indicates red blood cells in urine - hematuria
from kidney inflammation.
Oliguria - ✔✔✔ANSW✔✔..Condition caused by acute glomerulonephritis -
decreased urine output.
Urine-specific gravity in acute glomerulonephritis - ✔✔✔ANSW✔✔..Increases due
to fluid retention concentrating urine.
Positive ASO titer - ✔✔✔ANSW✔✔..Indicates streptococcal infection - antibody
to streptococcal antigen.
Metabolic acidosis - ✔✔✔ANSW✔✔..Acid-base imbalance with AKI/CRF -
kidneys can't excrete acid/produce bicarbonate.
Hyperkalemia - ✔✔✔ANSW✔✔..Risk factor for dysrhythmias - kidneys retain
potassium; elevated K+ causes cardiac arrhythmias.
Uremia - ✔✔✔ANSW✔✔..Crystallized urea deposits on skin with CRF (also
known as uremic frost).
Anemia in CRF - ✔✔✔ANSW✔✔..Caused by decreased erythropoietin (EPO)
production - kidneys make EPO for RBC production.
Potassium and phosphorus levels in CRF - ✔✔✔ANSW✔✔..Decrease - restrict to
prevent hyperkalemia and hyperphosphatemia.
, Growth spurts in adolescent males - ✔✔✔ANSW✔✔..Typically occur between
12.5-15.5 years.
First maturational change in girls - ✔✔✔ANSW✔✔..Breast development
(thelarche).
First maturational change in boys - ✔✔✔ANSW✔✔..Testicular enlargement
(genital growth).
Apnea of prematurity - ✔✔✔ANSW✔✔..Defined as a pause in breathing > 20
seconds.
Respiratory Distress Syndrome (RDS) - ✔✔✔ANSW✔✔..Breathing disorder from
lack of surfactant - also known as hyaline membrane disease.
L/S ratio < 2:1 significance - ✔✔✔ANSW✔✔..Indicates fetal lungs immature - high
risk for RDS; steroids given to accelerate lung maturity.
Pain location in appendicitis - ✔✔✔ANSW✔✔..Located at McBurney's point.
Sudden pain relief in appendicitis - ✔✔✔ANSW✔✔..Suggests appendix rupture -
peritoneal perforation.
Board-like abdomen from ruptured appendix - ✔✔✔ANSW✔✔..Indicates
peritonitis - bacterial peritoneal infection.
Albuterol - ✔✔✔ANSW✔✔..Bronchodilator for acute asthma attack - rapidly
relieves bronchospasm.
Status asthmaticus - ✔✔✔ANSW✔✔..Asthma exacerbation unresponsive to
treatment - life-threatening emergency.
Peak flow readings technique - ✔✔✔ANSW✔✔..Use average of 3 peak flow
readings - true; standard technique for accuracy.
(2025–2026 Edition)
Exam
his Pediatric Nursing NCLEX-RN preparation resource is aligned with the 2025–2026
NCLEX-RN® Test Plan and focuses on comprehensive pediatric nursing care a cross
developmental stages. Core domains include growth and development from infancy
through adolescence, pediatric assessment techniques, common childhood illnesses,
congenital conditions, pediatric pharmacology, family-centered care, child safety and
injury prevention, immunizations, and nutrition. Additional emphasis includes care of the
hospitalized child, pediatric emergencies, recognition and reporting of child abuse,
chronic conditions, developmental disabilities, psychosocial considerations, and end-of-
life care in pediatric populations. Content is structured to strengthen clinical judgment,
prioritization, and safe nursing interventions consistent with NCLEX-style questioning.
Designed to reinforce pediatric competency and support readiness for licensure-level
testing
Stimulants - ✔✔✔ANSW✔✔..Medication class used to treat ADHD
(methylphenidate, amphetamines) - increase dopamine/norepinephrine for
attention control.
Autism Spectrum Disorder (ASD) - ✔✔✔ANSW✔✔..Condition indicated by lack of
eye contact, repetitive behavior, and impaired social functioning - hallmark triad of
symptoms.
Growth monitoring in ADHD medications - ✔✔✔ANSW✔✔..Monitor
height/weight, vital signs (HR/BP), appetite - stimulants can suppress growth and
elevate vital signs.
Closed comedone - ✔✔✔ANSW✔✔..A whitehead - blocked pore with oil/bacteria
trapped beneath intact skin surface.
,Benzoyl peroxide - ✔✔✔ANSW✔✔..Topical acne treatment that bleaches fabrics
- oxidizing agent that permanently discolors sheets, towels, clothes.
Isotretinoin (Accutane) teaching - ✔✔✔ANSW✔✔..Severe teratogen—requires
two forms of birth control starting 1 month before, during, and 1 month after
treatment - mandatory iPLEDGE program, monthly negative pregnancy tests.
Acute glomerulonephritis common infection - ✔✔✔ANSW✔✔..Commonly follows
streptococcal infection (group A strep).
Cola-colored urine - ✔✔✔ANSW✔✔..Indicates red blood cells in urine - hematuria
from kidney inflammation.
Oliguria - ✔✔✔ANSW✔✔..Condition caused by acute glomerulonephritis -
decreased urine output.
Urine-specific gravity in acute glomerulonephritis - ✔✔✔ANSW✔✔..Increases due
to fluid retention concentrating urine.
Positive ASO titer - ✔✔✔ANSW✔✔..Indicates streptococcal infection - antibody
to streptococcal antigen.
Metabolic acidosis - ✔✔✔ANSW✔✔..Acid-base imbalance with AKI/CRF -
kidneys can't excrete acid/produce bicarbonate.
Hyperkalemia - ✔✔✔ANSW✔✔..Risk factor for dysrhythmias - kidneys retain
potassium; elevated K+ causes cardiac arrhythmias.
Uremia - ✔✔✔ANSW✔✔..Crystallized urea deposits on skin with CRF (also
known as uremic frost).
Anemia in CRF - ✔✔✔ANSW✔✔..Caused by decreased erythropoietin (EPO)
production - kidneys make EPO for RBC production.
Potassium and phosphorus levels in CRF - ✔✔✔ANSW✔✔..Decrease - restrict to
prevent hyperkalemia and hyperphosphatemia.
, Growth spurts in adolescent males - ✔✔✔ANSW✔✔..Typically occur between
12.5-15.5 years.
First maturational change in girls - ✔✔✔ANSW✔✔..Breast development
(thelarche).
First maturational change in boys - ✔✔✔ANSW✔✔..Testicular enlargement
(genital growth).
Apnea of prematurity - ✔✔✔ANSW✔✔..Defined as a pause in breathing > 20
seconds.
Respiratory Distress Syndrome (RDS) - ✔✔✔ANSW✔✔..Breathing disorder from
lack of surfactant - also known as hyaline membrane disease.
L/S ratio < 2:1 significance - ✔✔✔ANSW✔✔..Indicates fetal lungs immature - high
risk for RDS; steroids given to accelerate lung maturity.
Pain location in appendicitis - ✔✔✔ANSW✔✔..Located at McBurney's point.
Sudden pain relief in appendicitis - ✔✔✔ANSW✔✔..Suggests appendix rupture -
peritoneal perforation.
Board-like abdomen from ruptured appendix - ✔✔✔ANSW✔✔..Indicates
peritonitis - bacterial peritoneal infection.
Albuterol - ✔✔✔ANSW✔✔..Bronchodilator for acute asthma attack - rapidly
relieves bronchospasm.
Status asthmaticus - ✔✔✔ANSW✔✔..Asthma exacerbation unresponsive to
treatment - life-threatening emergency.
Peak flow readings technique - ✔✔✔ANSW✔✔..Use average of 3 peak flow
readings - true; standard technique for accuracy.
