1. Atherosclerosis
Answer Fibrous plaque form over fatty deposit and protrudes into lumen, partially or completely
obstructing blood flow
Usually attects larger vessels
coronary artery bed, aorta, carotids, vertebral, renal, femoral Fibrotic plaques become
calcified, hemorrhagic, ulcerated, or thrombosed
Attect all layers of vessel
Progression attected by genetics, chronic diseases (diabetes), lifestyle, exercise
2. Atherosclerosis Tx
Answer -HMG-CoA reductase inhibitors (statins)
-Ezetimibe
,-Combination drugs (e.g., ezetimibe with simvastatin)
-PCSK9 inhibitors - causes liver to reduce more LDL from the blood.
-Alirocumab/evolocumab
3. Artherosclerosis Client Teaching
Answer -Low risk people should have total serum cholesterol levels eval- uated every 4-6 years
-Those with risk factors and older than 40 years old should have evaluation more frequently
Modifiable risk factors
-Nutrition - must maintain a low-fat diet even when on medication
-Activity - encourage mild to moderate exercise
Drug therapy
4. Hypertension
Answer -85.7 million adults older than 20 years old have hypertension For
people over 60
,<150/90
For people under 60
<140/90
-patients whose blood pressures are above these goals should be treated with drug therapy and lifestyle modifications
5. Hypertension Tx Health Promotion
Answer -Weight reduction
-Restrict sodium
-Avoid catteine and tobacco
-Limit alcohol intake
-Stress management
-Aerobic Exercise 5 X week
-Diabetics - glucose control
, -Treat hyperlipidemia