Genetic Mutations POGIL Test Questions and Answers Rated A
How many nucleotides are present in the Insertion - A nucleotide is inserted into the DNA
"normal" DNA sequence in Model 1? - sequence
ANSWER -21 nucleotides Deletion - A nucleotide is deleted from the DNA
sequence
How many codons are contained in the mRNA
that is produced by the "normal" DNA in Model Would all substitution mutations lead to a change
1? - ANSWER -7 codons in the amino acid sequence? - ANSWER -
No, because some codons can code for the
same amino acid despite a nucleotide change
How many amino acids will be in the polypeptide
produced by the normal DNA/mRNA sequence?
- ANSWER -6 amino acids Would all insertion or deletion mutations lead to a
change in the amino acid sequence? -
ANSWER -Yes, because it manipulates
What is the amino acid sequence of the which sections are being coded
polypeptide produced by the "normal" DNA
sequence in Model 1? - ANSWER -Met His
Gln Trp Ile Thr What could potentially cause more damage (or a
greater benefit) to an organism, a substitution
mutation or an insertion mutation? -
Compare sequence 1&2 + effect of substitution - ANSWER -Insertion for the reason stated
ANSWER -5a. Sequence 2 has a G that above
replaced a C around the middle
5b. This changed Trp to Ser
What could potentially cause more damage (or a
greater benefit) to an organism, a deletion
Compare sequence 3&1 + effect of insertion - mutation at the beginning of a DNA sequence or
ANSWER -6a. T was inserted before a G at the end of a DNA sequence - ANSWER -
near the end of the first third of the DNA *(Unsure)* Both are pretty bad, but probably at
sequence the end because that could mean that the
6b. This caused all of the amino acids after His to translating wouldn't stop when it's supposed to
change, and the sequence no longer stops
All of the DNA and mRNA sequences in Model 1
Compare sequence 4&1 + effect of deletion - have ellipses (...) on one or both ends of the
sequences shown. Propose an explanation for
ANSWER -7a. The A after the C was
this use of this symbol in that context. -
deleted by slightly to the left of the middle of the
sequence ANSWER -The strands don't end until they
7b. This also changed all of the amino acids after get the stop codon
His, and the sequence also no longer stops
The amino acids produced from sequence 1 and
Define mutations - ANSWER -Substitution - sequence 2 in Model 1 do not have ellipses on
the end of them, however the amino acids
A nucleotide is substituted for another
produced from sequence 3 and sequence 4 do
1/3
How many nucleotides are present in the Insertion - A nucleotide is inserted into the DNA
"normal" DNA sequence in Model 1? - sequence
ANSWER -21 nucleotides Deletion - A nucleotide is deleted from the DNA
sequence
How many codons are contained in the mRNA
that is produced by the "normal" DNA in Model Would all substitution mutations lead to a change
1? - ANSWER -7 codons in the amino acid sequence? - ANSWER -
No, because some codons can code for the
same amino acid despite a nucleotide change
How many amino acids will be in the polypeptide
produced by the normal DNA/mRNA sequence?
- ANSWER -6 amino acids Would all insertion or deletion mutations lead to a
change in the amino acid sequence? -
ANSWER -Yes, because it manipulates
What is the amino acid sequence of the which sections are being coded
polypeptide produced by the "normal" DNA
sequence in Model 1? - ANSWER -Met His
Gln Trp Ile Thr What could potentially cause more damage (or a
greater benefit) to an organism, a substitution
mutation or an insertion mutation? -
Compare sequence 1&2 + effect of substitution - ANSWER -Insertion for the reason stated
ANSWER -5a. Sequence 2 has a G that above
replaced a C around the middle
5b. This changed Trp to Ser
What could potentially cause more damage (or a
greater benefit) to an organism, a deletion
Compare sequence 3&1 + effect of insertion - mutation at the beginning of a DNA sequence or
ANSWER -6a. T was inserted before a G at the end of a DNA sequence - ANSWER -
near the end of the first third of the DNA *(Unsure)* Both are pretty bad, but probably at
sequence the end because that could mean that the
6b. This caused all of the amino acids after His to translating wouldn't stop when it's supposed to
change, and the sequence no longer stops
All of the DNA and mRNA sequences in Model 1
Compare sequence 4&1 + effect of deletion - have ellipses (...) on one or both ends of the
sequences shown. Propose an explanation for
ANSWER -7a. The A after the C was
this use of this symbol in that context. -
deleted by slightly to the left of the middle of the
sequence ANSWER -The strands don't end until they
7b. This also changed all of the amino acids after get the stop codon
His, and the sequence also no longer stops
The amino acids produced from sequence 1 and
Define mutations - ANSWER -Substitution - sequence 2 in Model 1 do not have ellipses on
the end of them, however the amino acids
A nucleotide is substituted for another
produced from sequence 3 and sequence 4 do
1/3
