TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
Applied Pathophysiology A Conceptual Approach to the
g g g g g g ggggggg
Mechanisms of Disease 4th Edition
g g g g gg
(AnswersgaregatgthegEndgofgEachgChapter)g
Chapterg1:gIntroductiongtogPathophysiologyg
1.gThegnucleusg ,gwhichgisgessentialgforgfunctiongandgsurvivalgofgthegcell.g
A) isgthegsitegofgproteingsynthesisg
B) containsgtheggeneticgcodeg
C) transformsgcellulargenergyg
D) initiatesgaerobicgmetabolismg
2.gAlthoughgenergygisgnotgmadegingmitochondria,gtheygaregknowngasgthegpowergpla
ntsgofgthegcellgbecausegthey:g
A) containgRNAgforgproteingsynthesis.g
B) utilizegglycolysisgforgoxidativegenergy.g
C) extractgenergygfromgorganicgcompounds.g
D) storegcalciumgbondsgforgmusclegcontractions.g
3.gAlthoughgthegbasicgstructuregofgthegcellgplasmagmembranegisgformedgbygaglipi
dgbilayer,gmostgofgthegspecificgmembranegfunctionsgaregcarriedgoutgby:gA)gboundg
andgtransmembranegproteins.g
B) complex,glonggcarbohydrategchains.g
C) surfacegantigensgandghormonegreceptors.g
D) aggatinggsystemgofgselectivegiongchannels.g
4.gTogeffectivelygrelaygsignals,gcell-to-
cellgcommunicationgutilizesgchemicalgmessengergsystemsgthat:g
A) displacegsurfacegreceptorgproteins.g
B) accumulategwithingcellggapgjunctions.g
C) bindgtogcontractilegmicrofilaments.g
D) releasegsecretionsgintogextracellulargfluid.g
,TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
5.gAerobicgmetabolism,galsogknowngasgoxidativegmetabolism,gprovidesgenergygby:g
A) removinggthegphosphategbondsgfromgATP.g
B) combiningghydrogengandgoxygengtogformgwater.g
C) activatinggpyruvategstoredgingthegcytoplasm.g
D) breakinggdowngglucosegtogformglacticgacid.g
6.gExocytosis,gthegreversegofgendocytosis,gisgimportantging
intogthegextracellulargfluid.g
A) Engulfinggandgingestinggfluidgandgproteinsgforgtransportg
B) Killing,gdegrading,gandgdissolvinggharmfulgmicroorganismsg
C) Removinggcellulargdebrisgandgreleasinggsynthesizedgsubstancesg
D) Destructiongofgparticlesgbyglysosomalgenzymesgforgsecretiong
7.gThegprocessgresponsiblegforggeneratinggandgconductinggmembranegpotentialsgis:g
A)gdiffusiongofgcurrent-carryinggions.g
B) millivoltagegofgelectricalgpotential.g
C) polarizationgofgchargedgparticles.g
D) iongchannelgneurotransmission.g
8.gEpithelialgtissuesgaregclassifiedgaccordinggtogthegshapegofgthegcellsgandgthegn
umbergofglayers.gWhichgofgthegfollowinggisgagcorrectlygmatchedgdescription
gandgtypegofgepithelialgtissue?g
A) Simplegepithelium:gcellsgingcontactgwithgintercellulargmatrix;gsomegdognotg
extendgtogsurfaceg
B) Stratifiedgepithelium:gsingleglayergofgcells;gallgcellsgrestgongbasementgmem
braneg
C) Glandulargepithelium:garisegfromgsurfacegepitheliagandgunderlyinggconnecti
vegtissueg
D) Pseudostratifiedgepithelium:gmultipleglayersgofgcells;gdeepestglayergrestsgon
gbasementgmembraneg
9.gConnectivegtissuegcontainsgfibroblastsgthatgaregresponsiblegfor:gA
)gprovidinggagfibrousgframeworkgforgcapillaries.g
B) synthesisgofgcollagen,gelastin,gandgreticulargfibers.g
,TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
g g
C) forminggtendonsgandgthegfasciagthatgcoversgmuscles.g
D) fillinggspacesgbetweengtissuesgtogkeepgorgansgingplace.g
10.gAlthoughgallgmusclegtissuegcellsghavegsomegsimilarities,gsmoothgmuscleg(alsogkn
owngasginvoluntarygmuscle)gdiffersgby:g
A) havinggdensegbodiesgattachedgtogactingfilaments.g
B) containinggsarcomeresgbetweengZglinesgandgMgbands.g
C) havinggrapidgcontractionsgandgabundantgcross-striations.g
D) contractinggingresponsegtogincreasedgintracellulargcalcium.g
11.gWhichgofgthegfollowinggaspectsgofgthegfunctiongofgthegnucleusgisgperformedgbygri
bosomalgRNAg(rRNA)?g
A) CopyinggandgcarryinggDNAginstructionsgforgproteingsynthesisg
B) Carryinggaminogacidsgtogthegsitegofgproteingsynthesisg
C) Providinggthegsitegwheregproteingsynthesisgoccursg
D) Regulatinggandgcontrollinggproteingsynthesisg
12.gBreakdowngandgremovalgofgforeigngsubstancesgandgworn-
outgcellgpartsgaregperformedgbygwhichgofgthegfollowinggorganelles?g
A) Lysosomesg
B) Golgigapparatusg
C) Ribosomesg
D) Endoplasmicgreticulumg(ER)g
13.gImpairmentgingthegfunctiongofgperoxisomesgwouldgresultgin:gA
)g inadequategsitesgforgproteingsynthesis.g
B) anginabilitygtogtransportgcellulargproductsgacrossgthegcellgmembrane.g
C) insufficientgenergygproductiongwithingagcell.g
D) accumulationgofgfreegradicalsgingthegcytoplasm.g
14.gAftergseveralgmonthsgofgtryinggtogconceive,gagcouplegisgundergoinggfertilitygtes
ting.gSemenganalysisgindicatesgthatgthegmansgspermghavegdecreasedgmotility,g
agfindinggthatgisgthoughtgtogunderliegthegcouplesginabilitygtogbecomegpregnant.
g
, TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
Whichgofgthegfollowinggcellulargcomponentsgmaygbegdefectivegwithingthegmansg
sperm?g
A) Ribosomesg
B) Microtubulesg
C) Mitochondriag
D) Microfilamentsg
15.gWhichgofgthegfollowinggstatementsgisgtruegofgglycolysis?gA
)gGlycolysisgrequiresgoxygen.g
B) Glycolysisgoccursgingcellsgwithoutgmitochondria.g
C) Glycolysisgprovidesgthegmajoritygofgthegbodysgenergygneeds.g
D) Glycolysisgproducesgenergy,gwater,gandgcarbongdioxide.g
16.gWhichgofgthegfollowinggmembranegtransportgmechanismsgrequiresgtheggreatestga
mountgofgenergy?g
A) Facilitatedgdiffusiong
B) Passivegtransportg
C) Vesiculargtransportg
D) Simplegdiffusiong
17.gAgmalegpatientgwithgagdiagnosisgofgtypeg1gdiabetesgmellitusgisgexperiencingghyp
erglycemiagbecausegheglacksgsufficientginsulingtogincreasegthegavailabilitygofggl
ucosegtransportersginghisgcellgmembranes.gConsequently,ghisgcellsglackgintracel
lulargglucosegandgitgaccumulatesginghisgblood.gWhichgofgthegfollowinggprocess
esgwouldgbestgallowgglucosegtogcrossghisgcellgmembranes?g
A) Facilitatedgdiffusiong
B) Simplegdiffusiong
C) Secondarygactivegtransportg
D) Endocytosisg
18.gWhichgofgthegfollowinggstatementsgisgtruegofgskeletalgmusclegcells?g
A) Skeletalgmusclegcellsgeachghavegangapical,glateral,gandgbasalgsurface.g
B) Theygaregcloselygapposedgandgaregjoinedgbygcell-to-
cellgadhesiongmolecules.g
Applied Pathophysiology A Conceptual Approach to the
g g g g g g ggggggg
Mechanisms of Disease 4th Edition
g g g g gg
(AnswersgaregatgthegEndgofgEachgChapter)g
Chapterg1:gIntroductiongtogPathophysiologyg
1.gThegnucleusg ,gwhichgisgessentialgforgfunctiongandgsurvivalgofgthegcell.g
A) isgthegsitegofgproteingsynthesisg
B) containsgtheggeneticgcodeg
C) transformsgcellulargenergyg
D) initiatesgaerobicgmetabolismg
2.gAlthoughgenergygisgnotgmadegingmitochondria,gtheygaregknowngasgthegpowergpla
ntsgofgthegcellgbecausegthey:g
A) containgRNAgforgproteingsynthesis.g
B) utilizegglycolysisgforgoxidativegenergy.g
C) extractgenergygfromgorganicgcompounds.g
D) storegcalciumgbondsgforgmusclegcontractions.g
3.gAlthoughgthegbasicgstructuregofgthegcellgplasmagmembranegisgformedgbygaglipi
dgbilayer,gmostgofgthegspecificgmembranegfunctionsgaregcarriedgoutgby:gA)gboundg
andgtransmembranegproteins.g
B) complex,glonggcarbohydrategchains.g
C) surfacegantigensgandghormonegreceptors.g
D) aggatinggsystemgofgselectivegiongchannels.g
4.gTogeffectivelygrelaygsignals,gcell-to-
cellgcommunicationgutilizesgchemicalgmessengergsystemsgthat:g
A) displacegsurfacegreceptorgproteins.g
B) accumulategwithingcellggapgjunctions.g
C) bindgtogcontractilegmicrofilaments.g
D) releasegsecretionsgintogextracellulargfluid.g
,TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
5.gAerobicgmetabolism,galsogknowngasgoxidativegmetabolism,gprovidesgenergygby:g
A) removinggthegphosphategbondsgfromgATP.g
B) combiningghydrogengandgoxygengtogformgwater.g
C) activatinggpyruvategstoredgingthegcytoplasm.g
D) breakinggdowngglucosegtogformglacticgacid.g
6.gExocytosis,gthegreversegofgendocytosis,gisgimportantging
intogthegextracellulargfluid.g
A) Engulfinggandgingestinggfluidgandgproteinsgforgtransportg
B) Killing,gdegrading,gandgdissolvinggharmfulgmicroorganismsg
C) Removinggcellulargdebrisgandgreleasinggsynthesizedgsubstancesg
D) Destructiongofgparticlesgbyglysosomalgenzymesgforgsecretiong
7.gThegprocessgresponsiblegforggeneratinggandgconductinggmembranegpotentialsgis:g
A)gdiffusiongofgcurrent-carryinggions.g
B) millivoltagegofgelectricalgpotential.g
C) polarizationgofgchargedgparticles.g
D) iongchannelgneurotransmission.g
8.gEpithelialgtissuesgaregclassifiedgaccordinggtogthegshapegofgthegcellsgandgthegn
umbergofglayers.gWhichgofgthegfollowinggisgagcorrectlygmatchedgdescription
gandgtypegofgepithelialgtissue?g
A) Simplegepithelium:gcellsgingcontactgwithgintercellulargmatrix;gsomegdognotg
extendgtogsurfaceg
B) Stratifiedgepithelium:gsingleglayergofgcells;gallgcellsgrestgongbasementgmem
braneg
C) Glandulargepithelium:garisegfromgsurfacegepitheliagandgunderlyinggconnecti
vegtissueg
D) Pseudostratifiedgepithelium:gmultipleglayersgofgcells;gdeepestglayergrestsgon
gbasementgmembraneg
9.gConnectivegtissuegcontainsgfibroblastsgthatgaregresponsiblegfor:gA
)gprovidinggagfibrousgframeworkgforgcapillaries.g
B) synthesisgofgcollagen,gelastin,gandgreticulargfibers.g
,TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
g g
C) forminggtendonsgandgthegfasciagthatgcoversgmuscles.g
D) fillinggspacesgbetweengtissuesgtogkeepgorgansgingplace.g
10.gAlthoughgallgmusclegtissuegcellsghavegsomegsimilarities,gsmoothgmuscleg(alsogkn
owngasginvoluntarygmuscle)gdiffersgby:g
A) havinggdensegbodiesgattachedgtogactingfilaments.g
B) containinggsarcomeresgbetweengZglinesgandgMgbands.g
C) havinggrapidgcontractionsgandgabundantgcross-striations.g
D) contractinggingresponsegtogincreasedgintracellulargcalcium.g
11.gWhichgofgthegfollowinggaspectsgofgthegfunctiongofgthegnucleusgisgperformedgbygri
bosomalgRNAg(rRNA)?g
A) CopyinggandgcarryinggDNAginstructionsgforgproteingsynthesisg
B) Carryinggaminogacidsgtogthegsitegofgproteingsynthesisg
C) Providinggthegsitegwheregproteingsynthesisgoccursg
D) Regulatinggandgcontrollinggproteingsynthesisg
12.gBreakdowngandgremovalgofgforeigngsubstancesgandgworn-
outgcellgpartsgaregperformedgbygwhichgofgthegfollowinggorganelles?g
A) Lysosomesg
B) Golgigapparatusg
C) Ribosomesg
D) Endoplasmicgreticulumg(ER)g
13.gImpairmentgingthegfunctiongofgperoxisomesgwouldgresultgin:gA
)g inadequategsitesgforgproteingsynthesis.g
B) anginabilitygtogtransportgcellulargproductsgacrossgthegcellgmembrane.g
C) insufficientgenergygproductiongwithingagcell.g
D) accumulationgofgfreegradicalsgingthegcytoplasm.g
14.gAftergseveralgmonthsgofgtryinggtogconceive,gagcouplegisgundergoinggfertilitygtes
ting.gSemenganalysisgindicatesgthatgthegmansgspermghavegdecreasedgmotility,g
agfindinggthatgisgthoughtgtogunderliegthegcouplesginabilitygtogbecomegpregnant.
g
, TestgbankgforgAppliedgpathophysiologygagconceptualgapproachgtogthegmechanismsgofgdiseaseg4thgEdition.g
Whichgofgthegfollowinggcellulargcomponentsgmaygbegdefectivegwithingthegmansg
sperm?g
A) Ribosomesg
B) Microtubulesg
C) Mitochondriag
D) Microfilamentsg
15.gWhichgofgthegfollowinggstatementsgisgtruegofgglycolysis?gA
)gGlycolysisgrequiresgoxygen.g
B) Glycolysisgoccursgingcellsgwithoutgmitochondria.g
C) Glycolysisgprovidesgthegmajoritygofgthegbodysgenergygneeds.g
D) Glycolysisgproducesgenergy,gwater,gandgcarbongdioxide.g
16.gWhichgofgthegfollowinggmembranegtransportgmechanismsgrequiresgtheggreatestga
mountgofgenergy?g
A) Facilitatedgdiffusiong
B) Passivegtransportg
C) Vesiculargtransportg
D) Simplegdiffusiong
17.gAgmalegpatientgwithgagdiagnosisgofgtypeg1gdiabetesgmellitusgisgexperiencingghyp
erglycemiagbecausegheglacksgsufficientginsulingtogincreasegthegavailabilitygofggl
ucosegtransportersginghisgcellgmembranes.gConsequently,ghisgcellsglackgintracel
lulargglucosegandgitgaccumulatesginghisgblood.gWhichgofgthegfollowinggprocess
esgwouldgbestgallowgglucosegtogcrossghisgcellgmembranes?g
A) Facilitatedgdiffusiong
B) Simplegdiffusiong
C) Secondarygactivegtransportg
D) Endocytosisg
18.gWhichgofgthegfollowinggstatementsgisgtruegofgskeletalgmusclegcells?g
A) Skeletalgmusclegcellsgeachghavegangapical,glateral,gandgbasalgsurface.g
B) Theygaregcloselygapposedgandgaregjoinedgbygcell-to-
cellgadhesiongmolecules.g
