ACLS Pre Test 2026: Pharmacology and
Practical Application questions &
correct answers (Answers in Bold) New
A monitored patient in the ICU developed a sudden onset of narrow-complex
tachycardia at a rate of 220/min. The patient's blood pressure is 128/58 mm Hg, the
PETCO2 is 38 mm Hg, and the pulse oximetry reading is 98%. There is vascular access
in the left arm, and the patient has not been given any vasoactive drugs. A 12-lead ECG
confirms a supraventricular tachycardia with no evidence of ischemia or infarction. The
heart rate has not responded to vagal maneuvers. What is your next action?
Administer adenosine 6 mg IV push
Administer amiodarone 300 mg IV push
Perform synchronized cardioversion at 50 J
Perform synchronized cardioversion at 200 J - Administer adenosine 6 mg IV push
You arrive on the scene with the code team. High-quality CPR is in progress. An AED
has previously advised "no shock indicated." A rhythm check now finds asystole. After
resuming high-quality compressions, which action do you take next?
Call for a pulse check
Establish IV or IO access
Insert a laryngeal airway
Perform endotracheal intubation - Establish IV or IO access
You are caring for a 66-year-old man with a history of a large intracerebral hemorrhage
2 months ago. He is being evaluated for another acute stroke. The CT scan is negative
for hemorrhage. The patient is receiving oxygen via nasal cannula at 2 L/min, and an IV
has been established. His blood pressure is 180/100 mm Hg. Which drug do you
anticipate giving to this patient?
Aspirin
Glucose (D50)
Nicardipiner
tPA - Aspirin
In which situation does bradycardia require treatment?
12-lead ECG showing a normal sinus rhythm
Hypotension
Diastolic blood pressure greater than 90 mm Hg
Systolic blood pressure greater than 100 mm Hg - Hypotension
, Which intervention is most appropriate for the treatment of a patient in asystole?
Atropine
Defibrillation
Epinephrine
Transcutaneous pacing - Epinephrine
A patient with STEMI has ongoing chest discomfort. Heparin 4000 units IV bolus and a
heparin infusion of 1000 units per hour are being administered. The patient did not take
aspirin because he has a history of gastritis, which was treated 5 years ago. What is
your next action?
Give aspirin 160 to 325 mg to chew
Give clopidogrel 300 mg orally
Give enteric-coated aspirin 75 mg orally
Give enteric-coated aspirin 325 mg rectally - Give aspirin 160 to 325 mg to chew
Practical Application questions &
correct answers (Answers in Bold) New
A monitored patient in the ICU developed a sudden onset of narrow-complex
tachycardia at a rate of 220/min. The patient's blood pressure is 128/58 mm Hg, the
PETCO2 is 38 mm Hg, and the pulse oximetry reading is 98%. There is vascular access
in the left arm, and the patient has not been given any vasoactive drugs. A 12-lead ECG
confirms a supraventricular tachycardia with no evidence of ischemia or infarction. The
heart rate has not responded to vagal maneuvers. What is your next action?
Administer adenosine 6 mg IV push
Administer amiodarone 300 mg IV push
Perform synchronized cardioversion at 50 J
Perform synchronized cardioversion at 200 J - Administer adenosine 6 mg IV push
You arrive on the scene with the code team. High-quality CPR is in progress. An AED
has previously advised "no shock indicated." A rhythm check now finds asystole. After
resuming high-quality compressions, which action do you take next?
Call for a pulse check
Establish IV or IO access
Insert a laryngeal airway
Perform endotracheal intubation - Establish IV or IO access
You are caring for a 66-year-old man with a history of a large intracerebral hemorrhage
2 months ago. He is being evaluated for another acute stroke. The CT scan is negative
for hemorrhage. The patient is receiving oxygen via nasal cannula at 2 L/min, and an IV
has been established. His blood pressure is 180/100 mm Hg. Which drug do you
anticipate giving to this patient?
Aspirin
Glucose (D50)
Nicardipiner
tPA - Aspirin
In which situation does bradycardia require treatment?
12-lead ECG showing a normal sinus rhythm
Hypotension
Diastolic blood pressure greater than 90 mm Hg
Systolic blood pressure greater than 100 mm Hg - Hypotension
, Which intervention is most appropriate for the treatment of a patient in asystole?
Atropine
Defibrillation
Epinephrine
Transcutaneous pacing - Epinephrine
A patient with STEMI has ongoing chest discomfort. Heparin 4000 units IV bolus and a
heparin infusion of 1000 units per hour are being administered. The patient did not take
aspirin because he has a history of gastritis, which was treated 5 years ago. What is
your next action?
Give aspirin 160 to 325 mg to chew
Give clopidogrel 300 mg orally
Give enteric-coated aspirin 75 mg orally
Give enteric-coated aspirin 325 mg rectally - Give aspirin 160 to 325 mg to chew
