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ATI Fluid, Electrolyte, and Acid-Base Targeted Exam Questions and Answers 2026 Update | Complete Study Guide & Rationales

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Prepare confidently with the ATI Fluid, Electrolyte, and Acid-Base Targeted Exam Questions and Answers 2026 Update. This complete study guide includes verified practice questions, detailed rationales, and comprehensive coverage of fluid balance, electrolyte imbalances, acid-base disorders, nursing interventions, and clinical prioritization. Designed for RN nursing students preparing for ATI Targeted Medical-Surgical exams, this resource strengthens critical thinking, NCLEX-style question mastery, and exam readiness. Ideal for ATI remediation, exam preparation, and nursing success in 2026 and beyond.

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ATI Fluid, Electrolyte, And Acid-Base
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ATI Fluid, Electrolyte, and Acid-Base

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ATI Fluid, Electrolyte, and
Acid-Base Targeted Exam
Questions and Answers 2026
Update | Complete Study Guide &
Rationales
A nurse is admitting a client who reports nausea, vomiting, and weakness. The client has dry
oral mucous membranes and blood pressure 102/64 mm Hg. Which of the following findings
should the nurse identify as manifestations of fluid volume deficit? (Select all that apply.)

A. Decreased skin turgor
B. Concentrated urine
C. Bradycardia
D. Low-grade fever
E. Tachypnea - Answer- A; Decreased skin turgor is a manifestation present with fluid
volume deficit. Skin turgor is decreased due to the lack of fluid within the body and results in
dryness of the skin.
B; Concentrated urine is a manifestation present with fluid volume deficit. Urine is
concentrated due to lack of fluid in the vascular system, causing a decreased profusion of
the kidneys resulting in an increased urine specific gravity.
D; Low-grade fever is a manifestation present with fluid volume deficit. Low-grade fever is
one of the body's ways to maintain homeostasis to compensate for lack of fluid within the
body.
E; Tachypnea is a manifestation present with fluid volume deficit. Increased respirations are
the body's way to obtain oxygen due to the lack of fluid volume within the body.

A nurse is admitting an older adult client who reports a weight gain of 2.3 kg (5 lb) in 48 hr.
Which of the following manifestations of fluid volume excess should the nurse expect?
(Select all that apply.)

A. Dyspnea
B. Edema
C. Bradycardia
D. Hypertension
E. Weakness - Answer- A; Dyspnea is a manifestation present with fluid volume excess.
Dyspnea is due to an excess of fluids within the body and lungs, and the client is struggling
to breathe to obtain oxygen.
B; Weight gain can be a result of edema.
D; Blood pressure rises as the heart must work harder due to the excess fluid.
E; Weakness is due to the excess fluid that is retained, which depletes energy and increases
the workload for the body.

, A nurse is assessing a client who is dehydrated. Which of the following findings should the
nurse expect?

A. Moist skin
B. Distended neck veins
C. Increased urinary output
D. Tachycardia - Answer- D; Tachycardia is an attempt to maintain blood pressure, a
manifestation of fluid volume deficit.

A nurse is caring for a client in a long-term facility who has become weak, confused, and
experienced dizziness when standing. The client's temperature is 38.3 degrees C (100.9
degrees F), pulse 92/min, respirations 20/min, and blood pressure 108/60 mm Hg. Which of
the following actions should the nurse take?

A. Initiate fluid restrictions to limit intake
B. Check for peripheral edema
C. Encourage the client to ambulate to promote oxygenation
D. Monitor for orthostatic hypotension - Answer- D; Monitor for orthostatic hypotension
because they have manifestations of dehydration due to decreased circulatory volume.

A nurse is caring for a client who has a blood sodium level 133 mEg/L and blood potassium
level 3.4 mEq/L. The nurse should recognize that which of the following treatments can
result in these laboratory findings?

A. Three tap water enemas
B. 0.9% NaCl solution IV at 50 ml/hr
C. 5% dextrose with 0.45% NaCl solution with 20 mEq of K+ IV at 80 mL/hr
D. Antibiotic therapy - Answer- A; Three tap water enemas can result in a decrease in blood
sodium and potassium. Tap water is hypotonic, and gastrointestinal losses are isotonic. This
creates an imbalance and solute dilution.

A nurse is caring for a client who has a blood potassium 5.4 mEq/L. The nurse should
assess for which of the following manifestations?

A. ECG changes
B. Constipation
C. Polyuria
D. Paresthesia - Answer- A; Assess for ECG changes. Potassium levels can affect the heart
and result in arrhythmias.

A nurse is caring for a client who has a NGT attached to low intermittent suctioning. The
nurse should monitor for which of the following electrolyte imbalances?

A. Hypercalcemia
B. Hyponatremia
C. Hyperphosphatemia
D. Hyperkalemia - Answer- B; Monitor the client for hyponatremia. Nasogastric losses are
isotonic and contain sodium.

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ATI Fluid, Electrolyte, and Acid-Base
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ATI Fluid, Electrolyte, and Acid-Base

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