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What is the mechanism of action of SGLT2 inhibitors? - - ANSWER: - Blocks
glucose reabsorption in the kidney, increasing glucosuria and osmotic diuresis.
What are the common side effects of SGLT2 inhibitors? - - ANSWER: - Genital
fungal infections, urinary tract infections, increased urination, and hypotension.
What is the A1C reduction expected with SGLT2 inhibitors? - - ANSWER: - 0.5-
1%.
What is the mechanism of action of sulfonylureas? - - ANSWER: - Increases
pancreatic insulin secretion.
What are the key side effects of sulfonylureas? - - ANSWER: - Hypoglycemia
and weight gain.
What is the A1C reduction expected with sulfonylureas? - - ANSWER: - 1-1.5%.
,What is the mechanism of action for bile acid sequestrants like Colesevelam? - -
ANSWER: - May reduce hepatic glucose production, increase incretin levels, and
decrease GI glucose absorption.
What is the typical A1C reduction achieved by bile acid sequestrants? -
- ANSWER: - 0.5-1%
What are the advantages of using bile acid sequestrants? - - ANSWER: - No
hypoglycemia, weight neutral, safe in cardiovascular disease, lowers LDL.
What are common side effects of bile acid sequestrants? - - ANSWER: -
Constipation, nausea, bloating, dyspepsia.
What are contraindications for bile acid sequestrants? - - ANSWER: - Increased
triglycerides, pregnancy, drug interactions.
What is the mechanism of action for dopamine agonists like Bromocriptine? - -
ANSWER: - May centrally regulate metabolism and increase insulin sensitivity.
What is the typical A1C reduction achieved by dopamine agonists? -
- ANSWER: - 0.5-1%
,What are the advantages of using dopamine agonists? - - ANSWER: - No
hypoglycemia, weight neutral.
What are common side effects of dopamine agonists? - - ANSWER: - Dizziness,
syncope, headache, nausea, orthostatic hypotension.
What are contraindications for dopamine agonists? - - ANSWER: -
Pregnancy/lactation, syncope, migraines, antipsychotics.
What is the onset time for rapid-acting insulin like Lispro? - - ANSWER: - 15-30
minutes.
What is the peak action time for rapid-acting insulin? - - ANSWER: - 30 minutes
to 2.5 hours.
What is the duration of action for rapid-acting insulin? - - ANSWER: - 3-6.5
hours.
What are the key side effects of all insulin types? - - ANSWER: - Hypoglycemia,
weight gain, local injection site reactions, lipodystrophy.
, What is the recommended education for administering rapid-acting insulin? - -
ANSWER: - Give 15 minutes before meals or immediately after meals.
What is the onset time for short-acting insulin like Regular insulin? -
- ANSWER: - 30 minutes.
What is the peak action time for short-acting insulin? - - ANSWER: - 1-3 hours.
What is the duration of action for short-acting insulin? - - ANSWER: - 8 hours.
What is the recommended education for administering short-acting insulin? - -
ANSWER: - Give 30 minutes before meals.
What is the onset time for intermediate-acting insulin like NPH? - - ANSWER: -
1-2 hours.
What is the peak action time for intermediate-acting insulin? - - ANSWER: - 4-12
hours.
What is the duration of action for intermediate-acting insulin? - - ANSWER: - 16-
24 hours.