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Neurological Disorders Exam 3 (2026) – 400+ Questions on ALS, Myasthenia Gravis, GBS, Stroke, ICP & TBI

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This Neurological Disorders Exam 3 (2026) study guide contains over 400 detailed exam questions and answers covering major adult neurological conditions, emergency management, and high-priority nursing interventions. The material thoroughly reviews Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis (including myasthenic vs cholinergic crisis), Guillain-Barré Syndrome (ascending paralysis and respiratory monitoring), trigeminal neuralgia, brain tumors, intracranial pressure (ICP) management, and External Ventricular Drain (EVD) care, as outlined throughout pages 1–35. The guide provides in-depth coverage of increased ICP pathophysiology (Monro-Kellie doctrine, Cushing’s triad, cerebral herniation syndromes, GCS interpretation, EVD leveling at the external auditory meatus), stroke management (ischemic vs hemorrhagic, TPA inclusion/exclusion criteria, thrombectomy, NIHSS, BEFAST), and detailed complications such as cerebral edema, hemorrhagic transformation, aspiration, hyponatremia, and delayed cerebral ischemia. Advanced trauma content includes traumatic brain injury classifications (mild, moderate, severe by GCS), epidural vs subdural hematomas, basilar skull fractures (Battle’s sign, raccoon eyes), diffuse axonal injury, CSF leak identification (halo sign), and nursing priorities focused on airway protection, serial neurological assessments, seizure precautions, DVT prevention, and hemodynamic monitoring. Comprehensive nursing management principles are emphasized throughout, including priority assessments (AIRWAY first in ALS, GBS, and MG), vital capacity monitoring, aspiration precautions, positioning strategies to reduce ICP, hypertonic therapy (mannitol and 3–5% saline), sedation management, and interprofessional collaboration (PT, OT, ST, respiratory therapy). The structured question-and-answer format mirrors high-level nursing exam style testing and reinforces clinical reasoning, prioritization, and emergency recognition skills required for advanced medical-surgical and critical care nursing examinations. This document may concern: – Nursing students enrolled in Medical-Surgical Nursing courses – BSN students preparing for Neurological Disorders Exam 3 – ADN and RN students reviewing neuro content – Critical care nursing students – NCLEX-style exam preparation students – Nurse residency or transition-to-practice learners reviewing neuro emergencies Keywords: neurological disorders exam 3 2026 amyotrophic lateral sclerosis ALS myasthenia gravis crisis cholinergic vs myasthenic crisis guillain barre syndrome ascending paralysis vital capacity monitoring intracranial pressure management monro kellie doctrine cushing triad late sign external ventricular drain EVD leveling cerebral herniation syndrome ischemic vs hemorrhagic stroke TPA inclusion exclusion criteria NIHSS assessment BEFAST stroke acronym epidural vs subdural hematoma basilar skull fracture battle sign halo sign CSF leak diffuse axonal injury traumatic brain injury GCS mannitol hypertonic saline ICP cerebral edema cytotoxic vasogenic seizure precautions neuro aspiration precautions stroke

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Neurological Disorders EXAM 3
2026 Exam Questions and
Answers | A+ Score Assured



What is Amyotrophic Lateral Sclerosis (ALS)? - 🧠 ANSWER ✔✔a rapidly

progressing, (brain and spinal cord) disease that affects voluntary muscle

control. ALS results in gradual degeneration and death of motor neurons,

causing muscle weakness and atrophy, but does not impair the senses or

ability to think.

,What is the expected function of motor neurons? - 🧠 ANSWER ✔✔Motor

neurons are located throughout the CNS and serve as controlling and

communication links between the nervous system and voluntary muscles.

Messages are passed from upper motor neurons (located in the brain) to

lower motor neurons (located in the spinal cord) and on to particular

muscles to start movement and muscle contraction.


What is the pathology of ALS? - 🧠 ANSWER ✔✔ALS, both upper and lower

neurons degenerate and die. Unable to function, muscles gradually

weaken, atrophy, and twitch (fasciculation). The progressive degeneration

leads to death of the cells, resulting in the brain losing the ability to initiate

and control muscle movement. Eventually, all voluntary muscles are

affected, and patients are paralyzed, but sensation, thinking, and alertness

is still intact.


Is ALS fatal? - 🧠 ANSWER ✔✔yes. patients will typically die from

respiratory failure.


What are clinical manifestations of ALS? - 🧠 ANSWER ✔✔- a gradual onset

of muscle weakness

- Paralysis

,- muscle cramps

- muscle stiffness

- head drop

- tongue atrophy

- slurred speech

- voice changes

- difficulty swallowing

- weight loss

- dropping objects

- uncontrolled laughter/crying

What are the most concerning complications associated with ALS? - 🧠

ANSWER ✔✔- Respiratory failure / compromise


- Aspiration

- PE and DVT (impaired mobility)




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, Additional Complications:

- contractures (muscle atrophy)

- skin breakdown (impaired mobility)

- weight loss

- depression

what is the PRIORITY when caring for a patient with ALS? - 🧠 ANSWER

✔✔AIRWAY - teaching to watch for compromise of this would be very

important. Watching for a dusky skin color.

how do we know if a patient diagnosed with ALS is at risk for respiratory

compromise? - 🧠 ANSWER ✔✔- weakened cough


- impaired swallowing

- increased difficulty in breathing when lying flat.

- difficulty swallowing food or fluid

what causes respiratory failure in patients diagnosed with ALS? - 🧠

ANSWER ✔✔Loss of diaphragm's ability to contract and relax. Resulting in

inability to breath.

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