NBME BIOCHEMISTRY SHELF EXAM NEWEST
2026 QUESTIONS and CORRECT DETAILED
ANSWERS ALREADY GRADED A+
What is fiber? - CORRECT ANSWER-glucose beta(1->4) glucose bonded sugar;
body does not have beta(1-4) endoglucosidase
enterokinase - CORRECT ANSWER-activates trypsinogen; trypsin activates
chymotrypsin, procolipase, procarboxypeptidase, and proelastase
arsenic - CORRECT ANSWER-pyruvate dehydrogenase ib; smell of garlic
Which GLUT is insulin-dependent? - CORRECT ANSWER-GLUT4; found in
muscle & adipose
What is the role of F2,6BP? - CORRECT ANSWER-role player for insulin;
increases glycolysis for FA synth and glycogen synthesis
,What is significant about glucokinase? - CORRECT ANSWER-K_m is above
fasting concentration, V_max is very high
What promotes lactate buildup? - CORRECT ANSWER-^ NADH/NAD+
Where does lactate build up? - CORRECT ANSWER-eyes, testes, RBC's
What is the rate-limiting step of glycolysis? - CORRECT ANSWER-PFK,
allosterically activated by F2,6BP
Def in pyr kinase leads to... - CORRECT ANSWER-2,3BPG, G6P elevation due to
^ PEP
What steroid can be used to treat beta-blocker overdose? - CORRECT
ANSWER-glucagon
Which form of aldolase is liver-specific? - CORRECT ANSWER-B
triose phosphate isomerase - CORRECT ANSWER-G3P <-> DHAP; DHAP -
component of glycerol phosphate shuttle
, What TCA step makes GTP? - CORRECT ANSWER-succinate thiokinase
What neurotransmitter stimulates release of epinephrine from adrenal medulla? -
CORRECT ANSWER-acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What
is another assoc symptom? - CORRECT ANSWER-metanephrine; assoc with
HBP
What does acetazolamide (carbonic anhydrase ib) treat? - CORRECT ANSWER-
glaucoma, epilepsy, altitude sickness, congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - CORRECT ANSWER-pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - CORRECT ANSWER-Glu
HA protein of influenza binds to - CORRECT ANSWER-cytokine receptors
2026 QUESTIONS and CORRECT DETAILED
ANSWERS ALREADY GRADED A+
What is fiber? - CORRECT ANSWER-glucose beta(1->4) glucose bonded sugar;
body does not have beta(1-4) endoglucosidase
enterokinase - CORRECT ANSWER-activates trypsinogen; trypsin activates
chymotrypsin, procolipase, procarboxypeptidase, and proelastase
arsenic - CORRECT ANSWER-pyruvate dehydrogenase ib; smell of garlic
Which GLUT is insulin-dependent? - CORRECT ANSWER-GLUT4; found in
muscle & adipose
What is the role of F2,6BP? - CORRECT ANSWER-role player for insulin;
increases glycolysis for FA synth and glycogen synthesis
,What is significant about glucokinase? - CORRECT ANSWER-K_m is above
fasting concentration, V_max is very high
What promotes lactate buildup? - CORRECT ANSWER-^ NADH/NAD+
Where does lactate build up? - CORRECT ANSWER-eyes, testes, RBC's
What is the rate-limiting step of glycolysis? - CORRECT ANSWER-PFK,
allosterically activated by F2,6BP
Def in pyr kinase leads to... - CORRECT ANSWER-2,3BPG, G6P elevation due to
^ PEP
What steroid can be used to treat beta-blocker overdose? - CORRECT
ANSWER-glucagon
Which form of aldolase is liver-specific? - CORRECT ANSWER-B
triose phosphate isomerase - CORRECT ANSWER-G3P <-> DHAP; DHAP -
component of glycerol phosphate shuttle
, What TCA step makes GTP? - CORRECT ANSWER-succinate thiokinase
What neurotransmitter stimulates release of epinephrine from adrenal medulla? -
CORRECT ANSWER-acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What
is another assoc symptom? - CORRECT ANSWER-metanephrine; assoc with
HBP
What does acetazolamide (carbonic anhydrase ib) treat? - CORRECT ANSWER-
glaucoma, epilepsy, altitude sickness, congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - CORRECT ANSWER-pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - CORRECT ANSWER-Glu
HA protein of influenza binds to - CORRECT ANSWER-cytokine receptors
