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Which of the following is an example of a physical barrier?
a. ) Antibacterial fatty acids
b. ) Lysozymes in tears
c. ) Epithelial cells
d. ) Earwax
C. Epithelial cells
Epithelial cells form tight junctions that are a physical barrier to entry
for organisms. Sebaceous glands in the skin secrete antibacterial and
antifungal fatty acids. Earwax and lysozymes in tears are examples of
biochemical secretions that trap potential disease-causing
microorganisms.
Which statement is true regarding the inflammatory response?
a. ) Inflammatory response is the third line of defense.
b. ) Inflammatory response relies on cellular components only.
c. ) Inflammatory response generates a nonspecific response.
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d.) Inflammatory response occurs in nonvascular tissue.
c. ) Inflammatory response generates a nonspecific response.
The inflammatory response is the second line of defense. It occurs at the
site of tissue injury and generates a nonspecific response that involves
cellular and chemical components. The inflammatory response occurs in
tissues with a blood supply (vascularized).
Which receptor is expressed on macrophages and facilitates recognition
and phagocytosis of bacterial pathogens?
a. ) Complement receptors
b. ) Scavenger receptors
c. ) Toll-like receptors
d. )Pattern recognition receptors
b. ) Scavenger receptors
The scavenger receptors are primarily expressed on macrophages and
facilitate recognition and phagocytosis of bacterial pathogens.
Complement receptors recognize a variety of fragments produced
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through activation of the complement system. Toll-like receptors are
expressed on the surface of cells, including epithelial, mast, neutrophils,
macrophages, dendritic cells, and lymphocytes. They recognize
pathogen-associated molecular patterns or stressed host cells. Pattern
recognition receptors recognize patterns of infectious molecules. These
receptors are found on cells involved in innate resistance.
Which statement regarding mast cells is true?
a. ) Histamine causes vasoconstriction.
b. ) Mast cells are found only in blood vessels.
c. ) Snake bites, bee venoms, and toxins may cause activation.
d. ) Mast cells are not involved in allergic reactions.
c. ) Snake bites, bee venoms, and toxins may cause activation.
A number of things cause the activation of mast cells, including physical
injury, chemical agents (including toxins, bee venom, and snake bites),
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immunologic means, and activation of an inflammatory response.
Histamine is released from mast cells and causes vasodilation. Mast
cells are found in loose connective tissue close to blood vessels. Mast
cells are involved in initiating many allergic reactions.
Which term describes an acidic sulfur-containing lipid that produces
effects similar to histamine?
a. ) Leukotriene
b. ) Prostaglandin
c. ) Adhesion molecule
d. ) Phagocyte
a. ) Leukotriene
Leukotrienes act similar to histamine and cause smooth muscle
contraction, increased vascular permeability, and chemotaxis.
Prostaglandins cause increased vascular permeability, chemotaxis, and
pain. Adhesion molecules increase the stickiness between cells.
Phagocyte cells ingest and dispose of foreign material.
Which statement is true regarding neutrophils?