BIOD 331 | NURS 231 Pathophysiology
MODULE 4 EXAM
Actual Questions and Verified Answers
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Updated Module 4 Exam
True & False Questions
Multiple Choice Questions and Answers
, Expert-Verified Explanations
### Question 1
The coagulation cascade involves each of the following except:
- Make thrombocytes
Verified Explanation:
The coagulation cascade is responsible for the conversion of soluble plasma proteins into an
insoluble fibrin clot. It includes activation of intrinsic and extrinsic pathways, conversion of
prothrombin to thrombin, and fibrinogen to fibrin. Thrombocyte (platelet) formation is a
process called thrombopoiesis, primarily taking place in the bone marrow, and is not a direct
function of the coagulation cascade.
---
Which of the following increases the chance of clotting? Select all that apply.
- Protein C deficiency
Verified Explanation:
Protein C is a natural anticoagulant that degrades factors Va and VIIIa. Its deficiency results in a
loss of inhibitory control of the coagulation cascade, thus increasing clotting risk. In contrast,
vitamin K deficiency, vWF deficiency, and thrombocytopenia impair coagulation and increase
bleeding risk.
---
The three stages of hemostasis include each of the following except:
,- Vascular dilation
Verified Explanation:
Hemostasis refers to the cessation of bleeding and consists of: (1) vascular constriction, (2)
formation of a platelet plug, and (3) blood coagulation. Vascular dilation is not a component of
hemostasis and would, in fact, promote rather than prevent bleeding.
---
### Question 2
Which of the following medications would decrease a person’s risk for clotting? Select all that
apply.
- Heparin
- Warfarin
- Lovenox (enoxaparin)
Verified Explanation:
Heparin, warfarin, and Lovenox are anticoagulants that interfere with different aspects of
coagulation. Heparin and Lovenox (a low-molecular-weight heparin) enhance antithrombin III
activity, while warfarin inhibits vitamin K-dependent synthesis of clotting factors. Vitamin K is
needed for clotting factor synthesis and could promote clotting if used in excess.
---
A deficiency in which of the following would lead to a hypercoagulable state? Select all that
apply.
- Protein C
- Protein S
, - Antithrombin III
Verified Explanation:
Protein C, Protein S, and Antithrombin III are endogenous anticoagulants. Deficiencies in these
increase the risk for hypercoagulable states. Factors II, VII, IX, X, and prothrombin deficiencies
lead to bleeding disorders, not clotting.
---
### Question 3
Which of the following is NOT a hypercoagulable state? Select all that apply.
- Hemophilia A
- Hemophilia B
- Thrombocytopenia
Verified Explanation:
Hemophilia A and B are bleeding disorders caused by deficiencies of clotting factors VIII and IX,
respectively. Thrombocytopenia is a condition of decreased platelet number and is associated
with bleeding, not thrombosis (hypercoagulability).
---
Which of the following is a hypercoagulable state? Select all that apply.
- Congestive heart failure
- Smoking
- Postsurgical state
Verified Explanation:
MODULE 4 EXAM
Actual Questions and Verified Answers
100% Guarantee Pass
Portage Learning, Geneva College
Inside you will get:
Updated Module 4 Exam
True & False Questions
Multiple Choice Questions and Answers
, Expert-Verified Explanations
### Question 1
The coagulation cascade involves each of the following except:
- Make thrombocytes
Verified Explanation:
The coagulation cascade is responsible for the conversion of soluble plasma proteins into an
insoluble fibrin clot. It includes activation of intrinsic and extrinsic pathways, conversion of
prothrombin to thrombin, and fibrinogen to fibrin. Thrombocyte (platelet) formation is a
process called thrombopoiesis, primarily taking place in the bone marrow, and is not a direct
function of the coagulation cascade.
---
Which of the following increases the chance of clotting? Select all that apply.
- Protein C deficiency
Verified Explanation:
Protein C is a natural anticoagulant that degrades factors Va and VIIIa. Its deficiency results in a
loss of inhibitory control of the coagulation cascade, thus increasing clotting risk. In contrast,
vitamin K deficiency, vWF deficiency, and thrombocytopenia impair coagulation and increase
bleeding risk.
---
The three stages of hemostasis include each of the following except:
,- Vascular dilation
Verified Explanation:
Hemostasis refers to the cessation of bleeding and consists of: (1) vascular constriction, (2)
formation of a platelet plug, and (3) blood coagulation. Vascular dilation is not a component of
hemostasis and would, in fact, promote rather than prevent bleeding.
---
### Question 2
Which of the following medications would decrease a person’s risk for clotting? Select all that
apply.
- Heparin
- Warfarin
- Lovenox (enoxaparin)
Verified Explanation:
Heparin, warfarin, and Lovenox are anticoagulants that interfere with different aspects of
coagulation. Heparin and Lovenox (a low-molecular-weight heparin) enhance antithrombin III
activity, while warfarin inhibits vitamin K-dependent synthesis of clotting factors. Vitamin K is
needed for clotting factor synthesis and could promote clotting if used in excess.
---
A deficiency in which of the following would lead to a hypercoagulable state? Select all that
apply.
- Protein C
- Protein S
, - Antithrombin III
Verified Explanation:
Protein C, Protein S, and Antithrombin III are endogenous anticoagulants. Deficiencies in these
increase the risk for hypercoagulable states. Factors II, VII, IX, X, and prothrombin deficiencies
lead to bleeding disorders, not clotting.
---
### Question 3
Which of the following is NOT a hypercoagulable state? Select all that apply.
- Hemophilia A
- Hemophilia B
- Thrombocytopenia
Verified Explanation:
Hemophilia A and B are bleeding disorders caused by deficiencies of clotting factors VIII and IX,
respectively. Thrombocytopenia is a condition of decreased platelet number and is associated
with bleeding, not thrombosis (hypercoagulability).
---
Which of the following is a hypercoagulable state? Select all that apply.
- Congestive heart failure
- Smoking
- Postsurgical state
Verified Explanation:
