, ENDOCRIME SYSTEM Andregen
ADuctimob-alls
IMBALANCE-DIABETES MELLITUS
① Steroid hormone ,
synthesized from cholssard
ganadal formant Oestrogen
I
Progesterone TYPE I DIABETES
Adrenocortical hormone Glucocorticoid (cortise)
① Reason : cells become less sensitive to insult
[fuyes shing stan) Mineralo corticoids (aldustered①
Cocopter desensitation) > inactive insulin
Lipid-soluble
-
all insulin production
-
- cross membrane =>
the enters she >
-
no
Act on intracellular receptors (in
cytoplasm /nucleus) > activate all.
⑦ Body relies on for for
energy>
leads to
⑪ Associated with
obesity , poor dies , sedentary lifestyle
- Lipidaemia (excess fats in blood)
Mechanism of Action ⑪ Oven managable with exercise 2 diet,
① ⑭etusis : Themes
(fatty acid
by product) medication-
① Diffuse through plasma membrane
+ Kerracidosis : metabolic acidosis
① Bind to intracellular receptors (cytoplasm /nucleus life-threatening
② Form a receptor-hormone complex ⑪ Symptoms :
Polyuria , polyclipsia (thirst) weight loss ,
Blood glucose remain
high glucosaria
,
① Complex
directly
binds to DMA at a
specific gene region .
also non-diabetic people
⑪ Ketosis occurs in
during
⑤ Activates gene transcription MRMA
depleted
>
translation
star ration star :
glycogen storage is S
⑤ ribosomes
MRMA , protein synthesis via use fat for fuct
① polyaria dur se osmotic diuresis (18 tii that
① adaptation
:
Function Provin (Corris Tglucose
synthesis , ,
stress
thau Y
Fluid &
electroly balance (Aldosarone > TMat resention ,
+ +
)
Conte of Hormone Release
Reproduction 2 fertility (Herosserene,
oestrogen , progesteron)
Mood 2
Cognition (cortisul) Feedback Target response reduces inhibits furtherhormone release
⑦ Negative : or
Grunch 2 (rescosterone)
repair
metabolism .
Ex : Anterior
pituitary Secrets (n-stimulates varies/tests to produce astrogen/testosterone
Regulate
furtherreleasefrompoityspecific
High land of
ostgen/testrsorene inhibit further
BLOOD GLUCOSE HOMEO STASIS
Positive Feedback the to
① larger response amplifies event occurs
step ye
:
Pancreas gland digestive enzyme (acimar cell)
Exocrine secretes E Posterior secrates to an
during childbirth
·
pituitary oxy
:
Call : :
glucagon
Enducive gland hurmones from islets of
: secretes
Langerhans Ball : insulin
Oxytocin <↑ userine contractions >
Toxytocin release
Regulation of Blood Glucose : Normal
fasting blood glucose ~4-ommol/L
:
Modes of Hormone Release
BLOOD GLUCOSE IS LOW BLOOD GLUCOSE IS HIGH Endocrine gland stimulated
by :
a) Humoral Stimuli of ions /nutrients
changes in blood
: level
X-alls : -B-alls Secrete insulin
-
secte
glucagon :
Ex : Blood ↓ > parathyroid glands release Parathyroid
hormone > ↑Catlet > stimulus removed
Direct stimulates
- Acts on liver to :
- events
during absorptive phase ,
:
b) Meural Stimuli fibres
Here
directly stimulate endocine
glands
I
:
>
-
Glycogenolysis glycogen : >
-
glucose + / Glucose
uptake by body alls (esp muscle -
adipose) E: Sympathetic
nervous
system stimulates adrenal medullar > Tepinephrine 2
norepinephrine (flight-to-fight)
>
-
Gluconeogenesis
lactic and 2
:
production
new-carbohydrases leg
of
glucon
: amico
from
acids)
+
Glycogenesis glucose :
glycogen >
(in
/stored
muscle
in liver +
( Acrylcholine released from terminal of adrenal medulla > Acts on nicotinic
receptors > open
-
ion
>
-
Lipogenesis glucose : >
-
fat
adipocytes) channels > adrenalinal release
=> Release glucose into bloodstream
↑ membrane transport of glucose inte adipaye 2 myocyte
-
c) Hormonal Stimuli : Hormone released from one
g
land stimulate another endocrine
gland.
=> Blood normal.
Inhibit
glucose
3
rises to
Glycogenolysis
-
Blood glucose E: Hypothalamus releases tropin hormones > anterior
pituitary > release
piruicary
hormone
(eg : (4)
Gluconeogenesis >
normal alls secrete their hormone
> Stimulate
returns to
dipolysis target own
ADuctimob-alls
IMBALANCE-DIABETES MELLITUS
① Steroid hormone ,
synthesized from cholssard
ganadal formant Oestrogen
I
Progesterone TYPE I DIABETES
Adrenocortical hormone Glucocorticoid (cortise)
① Reason : cells become less sensitive to insult
[fuyes shing stan) Mineralo corticoids (aldustered①
Cocopter desensitation) > inactive insulin
Lipid-soluble
-
all insulin production
-
- cross membrane =>
the enters she >
-
no
Act on intracellular receptors (in
cytoplasm /nucleus) > activate all.
⑦ Body relies on for for
energy>
leads to
⑪ Associated with
obesity , poor dies , sedentary lifestyle
- Lipidaemia (excess fats in blood)
Mechanism of Action ⑪ Oven managable with exercise 2 diet,
① ⑭etusis : Themes
(fatty acid
by product) medication-
① Diffuse through plasma membrane
+ Kerracidosis : metabolic acidosis
① Bind to intracellular receptors (cytoplasm /nucleus life-threatening
② Form a receptor-hormone complex ⑪ Symptoms :
Polyuria , polyclipsia (thirst) weight loss ,
Blood glucose remain
high glucosaria
,
① Complex
directly
binds to DMA at a
specific gene region .
also non-diabetic people
⑪ Ketosis occurs in
during
⑤ Activates gene transcription MRMA
depleted
>
translation
star ration star :
glycogen storage is S
⑤ ribosomes
MRMA , protein synthesis via use fat for fuct
① polyaria dur se osmotic diuresis (18 tii that
① adaptation
:
Function Provin (Corris Tglucose
synthesis , ,
stress
thau Y
Fluid &
electroly balance (Aldosarone > TMat resention ,
+ +
)
Conte of Hormone Release
Reproduction 2 fertility (Herosserene,
oestrogen , progesteron)
Mood 2
Cognition (cortisul) Feedback Target response reduces inhibits furtherhormone release
⑦ Negative : or
Grunch 2 (rescosterone)
repair
metabolism .
Ex : Anterior
pituitary Secrets (n-stimulates varies/tests to produce astrogen/testosterone
Regulate
furtherreleasefrompoityspecific
High land of
ostgen/testrsorene inhibit further
BLOOD GLUCOSE HOMEO STASIS
Positive Feedback the to
① larger response amplifies event occurs
step ye
:
Pancreas gland digestive enzyme (acimar cell)
Exocrine secretes E Posterior secrates to an
during childbirth
·
pituitary oxy
:
Call : :
glucagon
Enducive gland hurmones from islets of
: secretes
Langerhans Ball : insulin
Oxytocin <↑ userine contractions >
Toxytocin release
Regulation of Blood Glucose : Normal
fasting blood glucose ~4-ommol/L
:
Modes of Hormone Release
BLOOD GLUCOSE IS LOW BLOOD GLUCOSE IS HIGH Endocrine gland stimulated
by :
a) Humoral Stimuli of ions /nutrients
changes in blood
: level
X-alls : -B-alls Secrete insulin
-
secte
glucagon :
Ex : Blood ↓ > parathyroid glands release Parathyroid
hormone > ↑Catlet > stimulus removed
Direct stimulates
- Acts on liver to :
- events
during absorptive phase ,
:
b) Meural Stimuli fibres
Here
directly stimulate endocine
glands
I
:
>
-
Glycogenolysis glycogen : >
-
glucose + / Glucose
uptake by body alls (esp muscle -
adipose) E: Sympathetic
nervous
system stimulates adrenal medullar > Tepinephrine 2
norepinephrine (flight-to-fight)
>
-
Gluconeogenesis
lactic and 2
:
production
new-carbohydrases leg
of
glucon
: amico
from
acids)
+
Glycogenesis glucose :
glycogen >
(in
/stored
muscle
in liver +
( Acrylcholine released from terminal of adrenal medulla > Acts on nicotinic
receptors > open
-
ion
>
-
Lipogenesis glucose : >
-
fat
adipocytes) channels > adrenalinal release
=> Release glucose into bloodstream
↑ membrane transport of glucose inte adipaye 2 myocyte
-
c) Hormonal Stimuli : Hormone released from one
g
land stimulate another endocrine
gland.
=> Blood normal.
Inhibit
glucose
3
rises to
Glycogenolysis
-
Blood glucose E: Hypothalamus releases tropin hormones > anterior
pituitary > release
piruicary
hormone
(eg : (4)
Gluconeogenesis >
normal alls secrete their hormone
> Stimulate
returns to
dipolysis target own
